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Complexity metrics and machine learning (ML) models have been utilized to analyze the lengths of segmental genomic entities like: exons, introns, intergenic and repeat/unique DNA sequences, in each of the 22 human chromosomes. The purpose…

The linking genotype to phenotype is the fundamental aim of modern genetics. We focus on study of links between gene expression data and phenotype data through integrative analysis. We propose three approaches. 1) The inherent complexity of…

Quantitative Methods · Quantitative Biology 2015-06-30 Min Xu

The aim of this work is to propose an ensemble of descriptors for Melanoma Classification, whose performance has been evaluated on validation and test datasets of the melanoma challenge 2018. The system proposed here achieves a strong…

Computer Vision and Pattern Recognition · Computer Science 2018-07-24 Loris Nanni , Alessandra Lumini , Stefano Ghidoni

In this study, we present a method of pattern mining based on network theory that enables the identification of protein structures or complexes from synthetic volume densities, without the knowledge of predefined templates or human biases…

Quantitative Methods · Quantitative Biology 2022-10-18 August George , Doo Nam Kim , Trevor Moser , Ian T. Gildea , James E. Evans , Margaret S. Cheung

Feature selection aims to identify the most pattern-discriminative feature subset. In prior literature, filter (e.g., backward elimination) and embedded (e.g., Lasso) methods have hyperparameters (e.g., top-K, score thresholding) and tie to…

Machine Learning · Computer Science 2024-03-07 Wangyang Ying , Dongjie Wang , Haifeng Chen , Yanjie Fu

Determining the types of neurons within a nervous system plays a significant role in the analysis of brain connectomics and the investigation of neurological diseases. However, the efficiency of utilizing anatomical, physiological, or…

Neurons and Cognition · Quantitative Biology 2024-03-27 Minghui Liao , Guojia Wan , Bo Du

We propose a novel model-selection method for dynamic networks. Our approach involves training a classifier on a large body of synthetic network data. The data is generated by simulating nine state-of-the-art random graph models for dynamic…

Social and Information Networks · Computer Science 2024-05-28 Lourens Touwen , Doina Bucur , Remco van der Hofstad , Alessandro Garavaglia , Nelly Litvak

Nowadays, hyperspectral image classification widely copes with spatial information to improve accuracy. One of the most popular way to integrate such information is to extract hierarchical features from a multiscale segmentation. In the…

Computer Vision and Pattern Recognition · Computer Science 2016-06-17 Yanwei Cui , Laetitia Chapel , Sébastien Lefèvre

Recent genomic and bioinformatic advances have motivated the development of numerous random network models purporting to describe graphs of biological, technological, and sociological origin. The success of a model has been evaluated by how…

Molecular Networks · Quantitative Biology 2007-05-23 Manuel Middendorf , Etay Ziv , Carter Adams , Jen Hom , Robin Koytcheff , Chaya Levovitz , Gregory Woods , Linda Chen , Chris Wiggins

While statistical analysis of a single network has received a lot of attention in recent years, with a focus on social networks, analysis of a sample of networks presents its own challenges which require a different set of analytic tools.…

Methodology · Statistics 2019-10-23 Jesús D. Arroyo-Relión , Daniel Kessler , Elizaveta Levina , Stephan F. Taylor

Convolutional Neural Networks (CNNs) are powerful models that achieve impressive results for image classification. In addition, pre-trained CNNs are also useful for other computer vision tasks as generic feature extractors. This paper aims…

Computer Vision and Pattern Recognition · Computer Science 2015-07-10 Ben Athiwaratkun , Keegan Kang

We introduce a new representation and feature extraction method for biological sequences. Named bio-vectors (BioVec) to refer to biological sequences in general with protein-vectors (ProtVec) for proteins (amino-acid sequences) and…

Quantitative Methods · Quantitative Biology 2016-05-30 Ehsaneddin Asgari , Mohammad R. K. Mofrad

This paper presents a novel ensemble framework to extract highly discriminative feature representation of image and its application for group-level happpiness intensity prediction in wild. In order to generate enough diversity of decisions,…

Computer Vision and Pattern Recognition · Computer Science 2017-08-01 Shitao Tang , Yichen Pan

Based on the DUSTGRAIN-pathfinder suite of simulations, we investigate observational degeneracies between nine models of modified gravity and massive neutrinos. Three types of machine learning techniques are tested for their ability to…

Cosmology and Nongalactic Astrophysics · Physics 2019-04-17 Julian Merten , Carlo Giocoli , Marco Baldi , Massimo Meneghetti , Austin Peel , Florian Lalande , Jean-Luc Starck , Valeria Pettorino

Based on the BioBricks standard, restriction synthesis is a novel catabolic iterative DNA synthesis method that utilizes endonucleases to synthesize a query sequence from a reference sequence. In this work, the reference sequence is built…

Signal Processing · Electrical Eng. & Systems 2020-12-14 Ethan J. Moyer , Anup Das

The discovery of nucleic acids and the structure of DNA have brought considerable advances in the understanding of life. The development of next-generation sequencing technologies has led to a large-scale generation of data, for which…

Molecular Networks · Quantitative Biology 2022-03-30 Murilo Montanini Breve , Matheus Henrique Pimenta-Zanon , Fabrício Martins Lopes

The increasing interest in complex networks research has been a consequence of several intrinsic features of this area, such as the generality of the approach to represent and model virtually any discrete system, and the incorporation of…

Sequence classification has a wide range of real-world applications in different domains, such as genome classification in health and anomaly detection in business. However, the lack of explicit features in sequence data makes it difficult…

Machine Learning · Computer Science 2023-06-19 Khaled Mohammed Saifuddin , Corey May , Farhan Tanvir , Muhammad Ifte Khairul Islam , Esra Akbas

Real networks exhibit nontrivial topological features such as heavy-tailed degree distribution, high clustering, and small-worldness. Researchers have developed several generative models for synthesizing artificial networks that are…

Social and Information Networks · Computer Science 2014-02-04 Sadegh Motallebi , Sadegh Aliakbary , Jafar Habibi

Recently, feature selection has become an increasingly important area of research due to the surge in high-dimensional datasets in all areas of modern life. A plethora of feature selection algorithms have been proposed, but it is difficult…

Neural and Evolutionary Computing · Computer Science 2019-10-24 Andrew Lensen , Bing Xue , Mengjie Zhang