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Polymer physics models suggest that chromatin spontaneously folds into loop networks with transcription units (TUs), such as enhancers and promoters, as anchors. Here we use combinatoric arguments to enumerate the emergent chromatin loop…

Biological Physics · Physics 2023-12-20 Andrea Bonato , Dom Corbett , Sergey Kitaev , Davide Marenduzzo , Alexander Morozov , Enzo Orlandini

One measure of geometrical complexity of a spatial curve is the number of crossings in a planar projection of the curve. For $N$-noded ring polymers with a fixed knot type, we evaluate numerically the average of the crossing number over…

Soft Condensed Matter · Physics 2016-08-31 Miyuki K. Shimamura , Tetsuo Deguchi

How long threadlike eukaryotic chromosomes fit tidily in the small volume of the nucleus without significant entanglement is just beginning to be understood, thanks to major advances in experimental techniques. Several polymer models, which…

Soft Condensed Matter · Physics 2024-10-03 D. Thirumalai , Guang Shi , Sucheol Shin , Changbong Hyeon

This report presents a unified treatment of the density of states for the knots and folds of polymer chains. The physical realization of such systems ranges from DNA molecules to the microscopic configurations of space-time.

Statistical Mechanics · Physics 2012-03-27 R. Kariotis

We use a suite of high resolution molecular cloud simulations carried out with the moving mesh code Arepo to explore the nature of star-forming filaments. The simulated filaments are identified and categorised from column density maps in…

Astrophysics of Galaxies · Physics 2015-06-22 Rowan J. Smith , Simon C. O. Glover , Ralf. S. Klessen

Following a number of conflicting studies of M87's mass profile, we undertake a dynamical analysis of multiple tracer populations to constrain its mass over a large radius range. We combine stellar kinematics in the central regions with the…

Astrophysics of Galaxies · Physics 2016-01-27 L. J. Oldham , M. W. Auger

Protein folding, peptide aggregation and crystallization, as well as adsorption of molecules on soft or solid substrates have an essential feature in common: In all these processes, structure formation is guided by a collective, cooperative…

Statistical Mechanics · Physics 2009-02-12 Michael Bachmann , Wolfhard Janke

We study polymers attached to spherical (circular) or paraboloidal (parabolic) probes in three (two) dimensions. Both self-avoiding and random walks are examined numerically. The behavior of a polymer of size $R_0$ attached to the tip of a…

Statistical Mechanics · Physics 2015-05-14 Roy Bubis , Yacov Kantor , Mehran Kardar

Branching architecture characterizes numerous systems, ranging from synthetic (hyper)branched polymers and biomolecules such as lignin, amylopectin, and nucleic acids to tracheal and neuronal networks. Its ubiquity reflects the many…

Soft Condensed Matter · Physics 2025-06-18 Domen Vaupotič , Jules Morand , Luca Tubiana , Anže Božič

Topological constraints (TCs) between polymers determine the behaviour of complex fluids such as creams, oils and plastics. Most of the polymer solutions used every day life employ linear chains; their behaviour is accurately captured by…

Soft Condensed Matter · Physics 2020-10-07 Fabio Landuzzi , Takenobu Nakamura , Davide Michieletto , Takahiro Sakaue

We have used neutron scattering to investigate the influence of concentration on the conformation of a star polymer. By varying the contrast between the solvent and isotopically labeled stars, we obtain the distributions of polymer and…

Via large-scale molecular dynamics simulations, we observe the melting of a topological glass of stiff ring polymers by incorporating flexible ring polymers, along an isobaric path. As more flexible ring polymers are introduced, cluster…

Soft Condensed Matter · Physics 2023-05-19 Projesh Kumar Roy , Pinaki Chaudhuri , Satyavani Vemparala

Drawing an analogy to the paradigm of quasi-elastic neutron scattering, we present a general approach for quantitatively investigating the spatiotemporal dependence of structural anisotropy relaxation in deformed polymers by using…

We study ground states of a hybrid system consisting of a polymer and an attractive nanowire by means of computer simulations. Depending on structural and energetic properties of the substrate, we find different adsorbed polymer…

Soft Condensed Matter · Physics 2011-03-10 Thomas Vogel , Michael Bachmann

Proteins, chain molecules of amino acids, behave in ways which are similar to each other yet quite distinct from standard compact polymers. We demonstrate that the Flory theorem, derived for polymer melts, holds for compact protein native…

Biomolecules · Quantitative Biology 2009-11-11 Jayanth R. Banavar , Trinh Xuan Hoang , Amos Maritan

A simple phenomenological model for describing the conformational dynamics of biological macromolecules via the nonlinearity-induced instabilities is proposed. It is shown that the interaction between charges and bending degrees of freedom…

Soft Condensed Matter · Physics 2009-11-11 Yu. B. Gaididei , P. L. Christiansen , W. J. Zakrzewski

By means of continuous space Monte Carlo simulation we study conformational structures formed by star and comb heteropolymers during kinetics of folding from the coil to the globule, as well as the corresponding equilibrium states on going…

Soft Condensed Matter · Physics 2007-05-23 E. G. Timoshenko , Yu. A. Kuznetsov

The correlations between the sequence of monomers in a polymer and its three-dimensional structure is a grand challenge in polymer science and biology. The properties and functions of macromolecules depend on their 3D shape that has…

Materials Science · Physics 2021-07-15 Ashwin A Bale , Tarak K Patra

The effective quasistatic conductivity of composite polymeric electrolytes is studied in terms of a hard-core--penetrable-layer model. Used to incorporate the interface phenomena (such as amorphization of the polymer matrix around filler…

Materials Science · Physics 2019-11-05 M. Ya. Sushko , A. K. Semenov

We define a class of random matrix ensembles that pertain to random looped polymers. Such random looped polymers are a possible model for bio-polymers such as chromatin in the cell nucleus. It is shown that the distribution of the largest…

Statistical Mechanics · Physics 2009-04-16 Dieter W. Heermann , Manfred Bohn