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Large particle sorters have potential applications in sorting microplastics and large biomaterials (>50 micrometer), such as tissues, spheroids, organoids, and embryos. Though great advancements have been made in image-based sorting of…

Sorting and separation of microparticles is a challenging problem of interdisciplinary nature. Existing technologies can differentiate microparticles by their bulk properties, such as size, density, electric polarizability, etc. The next…

Soft Condensed Matter · Physics 2018-09-03 Chenhui Peng , Taras Turiv , Yubing Guo , Qi-Huo Wei , Oleg D. Lavrentovich

Efficient particle sorting in microfluidic systems is vital for advancements in biomedical diagnostics and industrial applications. This study numerically investigates particle migration and passive sorting in symmetric serpentine…

Fluid Dynamics · Physics 2025-09-16 Sayan Karmakar , Anish Pal , Sourav Sarkar , Achintya Mukhopadhyay

Guided by extensive numerical simulations, we propose a microfluidic device that can sort elastic capsules by their deformability. The device consists of a duct embedded with a semi-cylindrical obstacle, and a diffuser which further…

Fluid Dynamics · Physics 2014-09-18 Lailai Zhu , Cecilia Rorai , Dhrubaditya Mitra , Luca Brandt

The ever-growing field of microfluidics requires precise and flexible control over fluid flow at the micro- and nanoscales. Current constraints demand a variety of controllable components for performing different operations inside closed…

In this letter, we describe the capillary sorting of particles by size based on dip coating. A substrate withdrawn from a liquid bath entrains a coating whose thickness depends on the withdrawal speed and the liquid properties. If the…

Soft Condensed Matter · Physics 2020-11-04 Brian M. Dincau , Martin Z. Bazant , Emilie Dressaire , Alban Sauret

Micro and nanoscale particles are crucial in various fields, from biomedical imaging to environmental processes. While conventional spectroscopy and microscopy methods for characterizing these particles often involve bulky equipment and…

Biological Physics · Physics 2024-11-26 Jie Liao , Maxwell Adolphson , Hangyue Li , Dipayon Kumar Sikder , Chenyang Lu , Lan Yang

We assess experimentally the ability of a simple flow-based sorting device, recently proposed numerically by [Zhu et al., Soft Matter, 2014, 10, 7705-7711], to separate capsules according to their stiffness. The device consists of a single…

Soft Condensed Matter · Physics 2021-01-01 Edgar Haner , Doriane Vesperini , Anne-Virginie Salsac , Anne Le Goff , Anne Juel

Pinched flow fractionation is shown to be an efficient and selective way to quickly separate particles by size in a very polydisperse semi-concentrated suspension. In an effort to optimize the method, we discuss the quantitative influence…

Fluid Dynamics · Physics 2012-04-17 Aparna Srivastav , Thomas Podgorski , Gwennou Coupier

Ultrasound-driven microbubbles rectify oscillatory motion into strong steady streaming flow [1, 2]. In this fluid dynamics video, we show size-dependent trapping, focusing and sorting of microparticles, utilizing the interaction between…

Fluid Dynamics · Physics 2010-10-19 Cheng Wang , Shreyas Jalikop , Sascha Hilgenfeldt

We introduce a method for analyzing the physical properties of nanoparticles in fluids via the competition between viscous drag and optical forces. By flowing particles through a microfluidic device containing an optical microcavity which…

Optics · Physics 2021-12-01 Kiana Malmir , William Okell , Aurélien A P Trichet , Jason M Smith

Specialized applications of nanoparticles often call for particular, well-characterized particle size distributions in solution. But, this property can prove difficult to measure. High-throughput methods, such as dynamic light scattering,…

Mesoscale and Nanoscale Physics · Physics 2021-09-24 Luke Melo , Angus Hui , Matt Kowal , Eric Boateng , Zahra Poursorkh , Edène Rocheron , Jake Wong , Ashton Christy , Edward Grant

Accurately measuring the size, morphology, and structure of nanoparticles is very important, because they are strongly dependent on their properties for many applications. In this paper, we present a deep-learning based method for…

Materials Science · Physics 2022-07-29 Claudius Zelenka , Marius Kamp , Kolja Strohm , Akram Kadoura , Jacob Johny , Reinhard Koch , Lorenz Kienle

Particle-wall interactions play a crucially important role in various applications such as microfluidic devices for cell sorting, particle separation, entire class of hydrodynamic filtration and its derivatives, etc. Yet, accurate…

Fluid Dynamics · Physics 2025-03-18 Aryan Mehboudi , Shrawan Singhal , S. V. Sreenivasan

An extended interference pattern close to surface may result in both a transmissive or evanescent surface fields for large area manipulation of trapped particles. The affinity of differing particle sizes to a moving standing wave light…

Rapid identification of microparticles in liquid is an important problem in environmental and biomedical applications such as for microplastic detection in water sources and physiological fluids. Existing spectro-scopic techniques are…

Applied Physics · Physics 2024-11-20 Yagmur Ceren Alatas , Uzay Tefek , Sayedus Salehin , Hashim Alhmoud , M. Selim Hanay

Plastic nanoparticles present technological opportunities and environmental concerns, but measurement challenges impede product development and hazard assessment. To meet these challenges, we advance a lateral nanoflow assay that integrates…

Soft Condensed Matter · Physics 2022-05-19 Kuo-Tang Liao , Andrew C. Madison , Adam L. Pintar , B. Robert Ilic , Craig R. Copeland , Samuel M. Stavis

Deterministic lateral displacement (DLD) devices separate micrometer-scale particles in solution based on their size using a laminar microfluidic flow in an array of obstacles. We investigate array geometries with rational row-shift…

High-Q optical resonators allow label-free detection of individual nanoparticles through perturbation of optical signatures but have practical limitations due to reliance on random diffusion to deliver particles to the sensing region. We…

Optics · Physics 2016-10-03 Jeewon Suh , Kewen Han , Christopher W Peterson , Gaurav Bahl

Efficient sorting of target cells is crucial for advancing cellular research in biology and medical diagnostics. Inertial microfluidics, an emerging technology, offers a promising approach for label-free particle sorting with high…

Fluid Dynamics · Physics 2023-08-04 Sayan Karmakar , Md Safwan Mondal , Anish Pal , Sourav Sarkar
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