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Low Dose Computed Tomography suffers from a high amount of noise and/or undersampling artefacts in the reconstructed image. In the current article, a Deep Learning technique is exploited as a regularization term for the iterative…

Image and Video Processing · Electrical Eng. & Systems 2019-06-04 Shabab Bazrafkan , Vincent Van Nieuwenhove , Joris Soons , Jan De Beenhouwer , Jan Sijbers

Regularization methods are commonly used in X-ray CT image reconstruction. Different regularization methods reflect the characterization of different prior knowledge of images. In a recent work, a new regularization method called a…

Medical Physics · Physics 2017-04-18 Wenxiang Cong , Ge Wang , Qingsong Yang , Jiang Hsieh , Jia Li , Rongjie Lai

Statistical image reconstruction (SIR) methods for X-ray CT produce high-quality and accurate images, while greatly reducing patient exposure to radiation. When further reducing X-ray dose to an ultra-low level by lowering the tube current,…

Medical Physics · Physics 2018-01-30 Qiaoqiao Ding , Yong Long , Xiaoqun Zhang , Jeffrey A. Fessler

Statistical image reconstruction (SIR) methods are studied extensively for X-ray computed tomography (CT) due to the potential of acquiring CT scans with reduced X-ray dose while maintaining image quality. However, the longer reconstruction…

Optimization and Control · Mathematics 2019-06-14 Hung Nien , Jeffrey A. Fessler

Low dose X-ray computed tomography (LDCT) is desirable for reduced patient dose. This work develops image reconstruction methods with deep learning (DL) regularization for LDCT. Our methods are based on unrolling of proximal…

Image and Video Processing · Electrical Eng. & Systems 2020-08-26 Qiaoqiao Ding , Gaoyu Chen , Xiaoqun Zhang , Qiu Huang , Hui Jiand Hao Gao

Low-dose CT image reconstruction has been a popular research topic in recent years. A typical reconstruction method based on post-log measurements is called penalized weighted-least squares (PWLS). Due to the underlying limitations of the…

Signal Processing · Electrical Eng. & Systems 2019-08-13 Siqi Ye , Saiprasad Ravishankar , Yong Long , Jeffrey A. Fessler

The field of medical image reconstruction has seen roughly four types of methods. The first type tended to be analytical methods, such as filtered back-projection (FBP) for X-ray computed tomography (CT) and the inverse Fourier transform…

Image and Video Processing · Electrical Eng. & Systems 2019-08-19 Saiprasad Ravishankar , Jong Chul Ye , Jeffrey A. Fessler

Sparse-view computed tomography (CT) is an effective method to reduce the radiation exposure in medical imaging. To reduce the severe streaking artifacts that occur in reconstructed images due to violation of the Nyquist/Shannon sampling…

Medical Physics · Physics 2026-03-17 Huiying Li , Yizhuang Song

A major challenge in computed tomography (CT) is to reduce X-ray dose to a low or even ultra-low level while maintaining the high quality of reconstructed images. We propose a new method for CT reconstruction that combines penalized…

Machine Learning · Statistics 2017-07-11 Xuehang Zheng , Zening Lu , Saiprasad Ravishankar , Yong Long , Jeffrey A. Fessler

X-ray tomography is a reliable tool for determining the inner structure of 3D object with penetrating X-rays. However, traditional reconstruction methods such as FDK require dense angular sampling in the data acquisition phase leading to…

Traditional model-based image reconstruction (MBIR) methods combine forward and noise models with simple object priors. Recent application of deep learning methods for image reconstruction provides a successful data-driven approach to…

Image and Video Processing · Electrical Eng. & Systems 2023-11-22 Ling Chen , Zhishen Huang , Yong Long , Saiprasad Ravishankar

Low-dose CT imaging requires reconstruction from noisy indirect measurements which can be defined as an ill-posed linear inverse problem. In addition to conventional FBP method in CT imaging, recent compressed sensing based methods exploit…

Image and Video Processing · Electrical Eng. & Systems 2025-11-14 Mehmet Ozan Unal , Metin Ertas , Isa Yildirim

Multi-energy CT takes advantage of the non-linearly varying attenuation properties of elemental media with respect to energy, enabling more precise material identification than single-energy CT. The increased precision comes with the cost…

Medical Physics · Physics 2020-02-14 Jussi Toivanen , Alexander Meaney , Samuli Siltanen , Ville Kolehmainen

Computed tomography (CT) involves a patient's exposure to ionizing radiation. To reduce the radiation dose, we can either lower the X-ray photon count or down-sample projection views. However, either of the ways often compromises image…

Image and Video Processing · Electrical Eng. & Systems 2023-10-12 Wenjun Xia , Yongyi Shi , Chuang Niu , Wenxiang Cong , Ge Wang

The iterative refinement method (IRM) has been very successfully applied in many different fields for examples the modern quantum chemical calculation and CT image reconstruction. It is proved that the refinement method can create an exact…

Medical Physics · Physics 2015-12-23 Kang Yang , Kevin Yang , Xintie Yang , Shuang-Ren Zhao

Computed Tomography (CT) is an essential non-destructive three dimensional imaging modality used in medicine, security screening, and inspection of manufactured components. Typical CT data acquisition entails the collection of a thousand or…

Medical Physics · Physics 2024-10-11 Kyle M. Champley , Michael B. Zellner , Joseph W. Tringe , Harry E. Martz

Image reconstruction from computed tomography (CT) measurement is a challenging statistical inverse problem since a high-dimensional conditional distribution needs to be estimated. Based on training data obtained from high-quality…

Image and Video Processing · Electrical Eng. & Systems 2020-06-12 Alexander Denker , Maximilian Schmidt , Johannes Leuschner , Peter Maass , Jens Behrmann

Purpose: Many useful image quality metrics for evaluating linear image reconstruction techniques do not apply to or are difficult to interpret for non-linear image reconstruction. The vast majority of metrics employed for evaluating…

To reduce the x-ray dose in computerized tomography (CT), many constrained optimization approaches have been proposed aiming at minimizing a regularizing function that measures lack of consistency with some prior knowledge about the object…

Medical Physics · Physics 2017-04-05 Edgar Garduño , Gabor T. Herman

Sparse-view Computed Tomography (CT) is an emerging protocol designed to reduce X-ray dose radiation in medical imaging. Traditional Filtered Back Projection algorithm reconstructions suffer from severe artifacts due to sparse data. In…

Numerical Analysis · Mathematics 2024-12-03 Elena Loli Piccolomini , Davide Evangelista , Elena Morotti
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