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Graph-based machine learning methods are useful tools in the identification and prediction of variation in genetic data. In particular, the comprehension of phenotypic effects at the cellular level is an accelerating research area in…

Quantitative Methods · Quantitative Biology 2024-12-06 Nandini Gadhia , Michalis Smyrnakis , Po-Yu Liu , Damer Blake , Melanie Hay , Anh Nguyen , Dominic Richards , Dong Xia , Ritesh Krishna

The explosion of activity in finding interactions in complex systems is driven by availability of copious observations of complex natural systems. However, such systems, e.g. the human brain, are rarely completely observable. Interaction…

Data Analysis, Statistics and Probability · Physics 2019-04-17 Danh-Tai Hoang , Junghyo Jo , Vipul Periwal

Quantifying diversity is of central importance for the study of structure, function and evolution of microbial communities. The estimation of microbial diversity has received renewed attention with the advent of large-scale metagenomic…

Populations and Evolution · Quantitative Biology 2013-08-06 Bart Haegeman , Jérôme Hamelin , John Moriarty , Peter Neal , Jonathan Dushoff , Joshua S. Weitz

Bacteria possess diverse mechanisms to regulate their motility in response to environmental and physiological signals, enabling them to navigate complex habitats and adapt their behavior. Among these mechanisms, interspecies recognition…

Populations and Evolution · Quantitative Biology 2025-12-01 Mattia Mattei , David Soriano Paños , Mahantesh Halappanavar , Alex Arenas

Specific protein-protein interactions are crucial in the cell, both to ensure the formation and stability of multi-protein complexes, and to enable signal transduction in various pathways. Functional interactions between proteins result in…

Biological Physics · Physics 2016-11-21 Anne-Florence Bitbol , Robert S. Dwyer , Lucy J. Colwell , Ned S. Wingreen

We extend the classical Susceptible-Infected-Recovered (SIR) model to a network-based framework where the degree distribution of nodes follows a Poisson distribution. This extension incorporates an additional parameter representing the mean…

Populations and Evolution · Quantitative Biology 2025-01-03 Josephine K. Wairimu , Andrew Gothard , Grzegorz A. Rempala

Social media and social networks have already woven themselves into the very fabric of everyday life. This results in a dramatic increase of social data capturing various relations between the users and their associated artifacts, both in…

Social and Information Networks · Computer Science 2023-06-22 Martin Atzmueller

We propose a novel dynamic network model to capture evolving latent communities within temporal networks. To achieve this, we decompose each observed dynamic edge between vertices using a Poisson-gamma edge partition model, assigning each…

Social and Information Networks · Computer Science 2024-11-19 Xincan Yu , Sikun Yang

The availability of high-throughput parallel methods for sequencing microbial communities is increasing our knowledge of the microbial world at an unprecedented rate. Though most attention has focused on determining lower-bounds on the…

Methodology · Statistics 2011-09-15 Manuel Lladser , Raúl Gouet , Jens Reeder

An important problem in the field of bioinformatics is to identify interactive effects among profiled variables for outcome prediction. In this paper, a logistic regression model with pairwise interactions among a set of binary covariates…

Artificial Intelligence · Computer Science 2016-12-30 Easton Li Xu , Xiaoning Qian , Tie Liu , Shuguang Cui

When modeling the dynamics of infectious disease, the incorporation of contact network information allows for the capture of the non-randomness and heterogeneity of realistic contact patterns. Oftentimes, it is assumed that the underlying…

Populations and Evolution · Quantitative Biology 2024-04-17 Maxwell H. Wang , Jukka-Pekka Onnela

Classic computational models of collective motion suggest that simple local averaging rules can promote many observed group level patterns. Recent studies, however, suggest that rules simpler than local averaging may be at play in real…

Adaptation and Self-Organizing Systems · Physics 2022-05-19 Vivek Jadhav , Vishwesha Guttal , Danny Raj M

Collective decision-making is a widespread phenomenon in both biological and artificial systems, where individuals reach a consensus through social interactions. While traditional models of opinion dynamics and contagion focus on pairwise…

Physics and Society · Physics 2025-10-02 David March-Pons , Romualdo Pastor-Satorras , M. Carmen Miguel

There is a growing awareness of the important roles that microbial communities play in complex biological processes. Modern investigation of these often uses next generation sequencing of metagenomic samples to determine community…

Applications · Statistics 2018-01-25 Adrian Dobra , Camilo Valdes , Dragana Ajdic , Bertrand Clarke , Jennifer Clarke

Protein-protein interactions drive many biological processes, including the detection of phytopathogens by plants' R-Proteins and cell surface receptors. Many machine learning studies have attempted to predict protein-protein interactions…

Machine Learning · Computer Science 2023-10-24 Ruth Veevers , Dan MacLean

Imitation is a basic updating mechanism for strategy evolution in structured populations, determining how individuals sample social information and translate it into behavioral changes. Higher-order networks, such as hypergraphs, generalize…

Physics and Society · Physics 2026-02-11 Bingxin Lin , Lei Zhou , Hao Fang

Predicting pedestrians' trajectories is a crucial capability for autonomous vehicles' safe navigation, especially in spaces shared with pedestrians. Pedestrian motion in shared spaces is influenced by both the presence of vehicles and other…

Robotics · Computer Science 2023-08-15 Mahsa Golchoubian , Moojan Ghafurian , Kerstin Dautenhahn , Nasser Lashgarian Azad

Complex systems are often characterized by distinct types of interactions between the same entities. These can be described as a multilayer network where each layer represents one type of interaction. These layers may be interdependent in…

Social and Information Networks · Computer Science 2018-08-21 Caterina De Bacco , Eleanor A. Power , Daniel B. Larremore , Cristopher Moore

Real-world complex systems such as ecological communities and neuron networks are essential parts of our everyday lives. These systems are composed of units which interact through intricate networks. The ability to predict sudden changes in…

Adaptation and Self-Organizing Systems · Physics 2019-07-05 Deniz Eroglu , Matteo Tanzi , Sebastian van Strien , Tiago Pereira

We introduce the Poisson Hierarchical Indian Buffet Process (PHIBP), a new class of species sampling models designed to address the challenges of complex, sparse count data by facilitating information sharing across and within groups. Our…

Machine Learning · Statistics 2025-08-26 Lancelot F. James , Juho Lee , Abhinav Pandey
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