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Because biological processes can make different loci have different evolutionary histories, species tree estimation requires multiple loci from across the genome. While many processes can result in discord between gene trees and species…

Quantitative Methods · Quantitative Biology 2018-03-13 Md. Shamsuzzoha Bayzid , Siavash Mirarab , Bastien Boussau , Tandy Warnow

We present here an overview of the Fourier Transform Scanning Tunneling spectroscopy technique (FT-STS). This technique allows one to probe the electronic properties of a two-dimensional system by analyzing the standing waves formed in the…

Mesoscale and Nanoscale Physics · Physics 2015-05-28 L. Simon , C. Bena , F. Vonau , M. Cranney , D. Aubel

We introduce a method---called Fisher exact scanning (FES)---for testing and identifying variable dependency that generalizes Fisher's exact test on $2\times 2$ contingency tables to $R\times C$ contingency tables and continuous sample…

Methodology · Statistics 2017-05-03 Li Ma , Jialiang Mao

In classical sparse representation based classification and weighted SRC algorithms, the test samples are sparely represented by all training samples. They emphasize the sparsity of the coding coefficients but without considering the local…

Applications · Statistics 2017-02-17 Shanwen Zhang , Harry Wang , Wenzhun Huang

Spatial transcriptomics (ST) provides essential spatial context by mapping gene expression within tissue, enabling detailed study of cellular heterogeneity and tissue organization. However, aligning ST data with histology images poses…

Aiming at recognizing the samples from novel categories with few reference samples, few-shot learning (FSL) is a challenging problem. We found that the existing works often build their few-shot model based on the image-level feature by…

Computer Vision and Pattern Recognition · Computer Science 2021-11-09 Junying Huang , Fan Chen , Keze Wang , Liang Lin , Dongyu Zhang

Few-Shot Classification(FSC) aims to generalize from base classes to novel classes given very limited labeled samples, which is an important step on the path toward human-like machine learning. State-of-the-art solutions involve learning to…

Computer Vision and Pattern Recognition · Computer Science 2024-09-05 Xiongkun Linghu , Yan Bai , Yihang Lou , Shengsen Wu , Jinze Li , Jianzhong He , Tao Bai

For many complex diseases, prognosis is of essential importance. It has been shown that, beyond the main effects of genetic (G) and environmental (E) risk factors, the gene-environment (G$\times$E) interactions also play a critical role. In…

Applications · Statistics 2015-05-15 Hao Chai , Qingzhao Zhang , Yu Jiang , Guohua Wang , Sanguo Zhang , Shuangge Ma

Spatial Transcriptomics (ST) is a technology that measures gene expression profiles within tissue sections while retaining spatial context. It reveals localized gene expression patterns and tissue heterogeneity, both of which are essential…

Quantitative Methods · Quantitative Biology 2026-03-24 Wei Zhang , Jiajun Chu , Xinci Liu , Chen Tong , Xinyue Li

Large-scale statistical analysis of data sets associated with genome sequences plays an important role in modern biology. A key component of such statistical analyses is the computation of $p$-values and confidence bounds for statistics…

Applications · Statistics 2011-01-06 Peter J. Bickel , Nathan Boley , James B. Brown , Haiyan Huang , Nancy R. Zhang

Fluorescence microscopy is widely used for the study of biological specimens. Deconvolution can significantly improve the resolution and contrast of images produced using fluorescence microscopy; in particular, Bayesian-based methods have…

Methodology · Statistics 2015-02-04 Alexander Wong , Xiao Yu Wang , Maud Gorbet

As researchers collect increasingly large molecular data sets to reconstruct the Tree of Life, the heterogeneity of signals in the genomes of diverse organisms poses challenges for traditional phylogenetic analysis. A class of phylogenetic…

Populations and Evolution · Quantitative Biology 2015-09-11 Liang Liu , Zhenxiang Xi , Shaoyuan Wu , Charles Davis , Scott V. Edwards

We propose a domain adaptation approach for object detection. We introduce a two-step method: the first step makes the detector robust to low-level differences and the second step adapts the classifiers to changes in the high-level…

Computer Vision and Pattern Recognition · Computer Science 2019-11-25 Adrian Lopez Rodriguez , Krystian Mikolajczyk

A fine-grained comparison of generative models requires the identification of sample types generated differently by each of the involved models. While quantitative scores have been proposed in the literature to rank different generative…

Machine Learning · Computer Science 2025-07-16 Jingwei Zhang , Mohammad Jalali , Cheuk Ting Li , Farzan Farnia

In a typical supervised machine learning setting, the predictions on all test instances are based on a common subset of features discovered during model training. However, using a different subset of features that is most informative for…

Machine Learning · Computer Science 2021-06-10 Yasitha Warahena Liyanage , Daphney-Stavroula Zois , Charalampos Chelmis

Many datasets include a small set of variables, such as biomarkers or clinical outcomes, whose relationships to the broader system are of primary scientific interest. Estimating the full network of inter-variable relationships in such…

Methodology · Statistics 2026-05-14 Omar Melikechi , David B. Dunson , Noureddine Melikechi , Jeffrey W. Miller

Positive selection distorts the structure of genealogies and hence alters patterns of genetic variation within a population. Most analyses of these distortions focus on the signatures of hitchhiking due to hard or soft selective sweeps at a…

Populations and Evolution · Quantitative Biology 2012-08-17 Michael M. Desai , Aleksandra M. Walczak , Daniel S. Fisher

Scanning transmission electron microscopy (STEM) is now the primary tool for exploring functional materials on the atomic level. Often, features of interest are highly localized in specific regions in the material, such as ferroelectric…

Materials Science · Physics 2021-08-11 Nicole Creange , Ondrej Dyck , Rama K. Vasudevan , Maxim Ziatdinov , Sergei V. Kalinin

Rejecting the null hypothesis in two-sample testing is a fundamental tool for scientific discovery. Yet, aside from concluding that two samples do not come from the same probability distribution, it is often of interest to characterize how…

Statistics Theory · Mathematics 2021-09-08 Boris Landa , Rihao Qu , Joseph Chang , Yuval Kluger

We apply recently developed inference methods based on general coalescent processes to DNA sequence data obtained from various marine species. Several of these species are believed to exhibit so-called shallow gene genealogies, potentially…

Populations and Evolution · Quantitative Biology 2012-11-06 Matthias Steinrücken , Matthias Birkner , Jochen Blath
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