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During the last years, a well studied biological substrate, namely Physarum polycephalum, has been proven efficient on finding appropriate and efficient solutions in hard to solve complex mathematical problems. The plasmodium of P.…

Slime mould Physarum polycephalum is a single cell visible by unaided eye. Let the slime mould span two electrodes with a single protoplasmic tube: if the tube is heated to approximately 40{\deg}C, the electrical resistance of the…

Emerging Technologies · Computer Science 2015-12-09 Xavier Alexis Walter , Ian Horsfield , Richard Mayne , Ioannis A. Ieropoulos , Andrew Adamatzky

Plasmodium of \emph{Physarum polycephalum} is a single cell visible by unaided eye. The plasmodium's foraging behaviour is interpreted in terms of computation. Input data is a configuration of nutrients, result of computation is a network…

Pattern Formation and Solitons · Physics 2015-03-17 Jeff Jones , Andrew Adamatzky

Physarum polycephalum is a huge single cell with thousands of nuclei, which behaves like a giant amoeba. During its foraging behaviour this plasmodium produces electrical activity corresponding to different physiological states. We…

Pattern Formation and Solitons · Physics 2012-12-12 Eduardo R. Miranda , Andrew Adamatzky , Jeff Jones

In recent years, research on Physarum polycephalum has become more popular after Nakagaki et al. (2000) performed their famous experiment showing that Physarum was able to find the shortest route through a maze. Subsequent researches have…

Artificial Intelligence · Computer Science 2021-05-11 Abubakr Awad , Wei Pang , David Lusseau , George M. Coghill

The plasmodium of slime mould Physarum polycephalum behaves as an amorphous reaction-diffusion computing substrate and is capable of apparently intelligent behaviour. But how does intelligence emerge in an acellular organism? Through a…

Emerging Technologies · Computer Science 2015-03-11 Richard Mayne , Andrew Adamatzky , Jeff Jones

In this demo, we present a novel technique for approximating topologically optimal scaffoldings for 3D printed objects using a Monte Carlo algorithm based on the foraging behavior of the Physarum polycephalum slime mold. As a case study, we…

Graphics · Computer Science 2022-12-23 Drew Ehrlich , Milad Hakimshafaei , Oskar Elek

The model organism Physarum polycephalum is known to perform decentralised problem solving despite absence of nervous system. Experimental evidence and modelling studies have linked these abilities, and in particular maze-solving, to some…

Biological Physics · Physics 2026-02-19 Daniele Proverbio , Giulia Giordano

Life evolved organisms to adapt dynamically to their environment and autonomously exhibit behaviours. While complex behaviours in organisms are typically associated with the capability of neurons to process information, the unicellular…

Biological Physics · Physics 2023-06-16 Mathieu Le Verge-Serandour , Karen Alim

Slime mould Physarum polycephalum is a large single cell visible by unaided eye. We design a slime mould implementation of a tactile hair, where the slime mould responds to repeated deflection of hair by an immediate high-amplitude spike…

Emerging Technologies · Computer Science 2013-06-13 Andrew Adamatzky

Plasmodium of Physarum polycephalum is a large cell capable of solving graph-theoretic, optimization and computational geometry problems due to its unique foraging behavior. Also the plasmodium is unique biological substrate that mimics…

Adaptation and Self-Organizing Systems · Physics 2010-11-23 Andrew Adamatzky , Jeff Jones

Plasmodium of \emph{Physarum polycephalum} is a single huge (visible by naked eye) cell with myriad of nuclei. The plasmodium is a promising substrate for non-classical, nature-inspired, computing devices. It is capable for approximation of…

Robotics · Computer Science 2010-11-23 Andrew Adamatzky

Plasmodium stage of Physarum polycephalum behaves as a distributed dynamical pattern formation mechanism who's foraging and migration is influenced by local stimuli from a wide range of attractants and repellents. Complex protoplasmic tube…

Biological Physics · Physics 2012-04-10 Soichiro Tsuda , Jeff Jones , Andrew Adamatzky , Jonathan Mills

Plasmodium of Physarum polycephalum is a single cell visible by unaided eye, which spans sources of nutrients with its protoplasmic network. In a very simple experimental setup we recorded electric potential of the propagating plasmodium.…

Pattern Formation and Solitons · Physics 2011-07-18 Andrew Adamatzky , Jeff Jones

We construct electronic oscillator from acellular slime mould Physarum polycephalum. The slime mould oscillator is made of two electrodes connected by a protoplasmic tube of the living slime mould. A protoplasmic tube has an average…

Emerging Technologies · Computer Science 2014-03-31 Andrew Adamatzky

Purpose: Protoplasmic tubes of Physarum polycephalum, also know as Physarum Wires (PW), have been previously suggested as novel bio- electronic components. Until recently, practical examples of electronic circuits using PWs have been…

Emerging Technologies · Computer Science 2015-11-26 James G. H. Whiting , Richard Mayne , Nadine Moody , Ben de Lacy Costello , Andrew Adamatzky

P. polycephalum may be considered as a spatially represented parallel unconventional computing substrate, but how can this `computer' be programmed? In this paper we examine and catalogue individual low-level mechanisms which may be used to…

Emerging Technologies · Computer Science 2016-10-23 Jeff Jones

While computational capacity limits of the universe and carbon-based life have been estimated, a stricter bound for aneural organisms has not been established. Physarum polycephalum, a unicellular, multinucleated amoeba, is capable of…

Quantum Physics · Physics 2025-10-24 Suyash Bajpai , Aviva Lucas-DeMott , Nirosha J Murugan , Michael Levin , Philip Kurian

The slime mould Physarum polycephalum is known to construct proto- plasmic transport networks which approximate proximity graphs by forag- ing for nutrients during its plasmodial life cycle stage. In these networks, nodes are represented by…

Emerging Technologies · Computer Science 2015-11-19 Jeff Jones , Richard Mayne , Andrew Adamatzky

Computer simulations have become a very powerful tool for scientific research. In order to facilitate research in computational biology, the BioDynaMo project aims at a general platform for biological computer simulations, which should be…

Distributed, Parallel, and Cluster Computing · Computer Science 2016-08-18 Lukas Breitwieser , Roman Bauer , Alberto Di Meglio , Leonard Johard , Marcus Kaiser , Marco Manca , Manuel Mazzara , Fons Rademakers , Max Talanov