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Positron emission tomography (PET) is a cornerstone of modern radiology. The ability to detect cancer and metastases in whole body scans fundamentally changed cancer diagnosis and treatment. One of the main bottlenecks in the clinical…

Computer Vision and Pattern Recognition · Computer Science 2022-04-28 Ida Häggström , C. Ross Schmidtlein , Gabriele Campanella , Thomas J. Fuchs

Low-count reconstruction remains a challenge for Positron Emission Tomography (PET) even with the recent progress in time-of-flight (TOF) resolution. In this context, the bias between the acquired histogram, consisting of low values or…

Medical Physics · Physics 2023-01-12 Maxime Toussaint , Francis Loignon-Houle , Roger Lecomte , Jean-Pierre Dussault

The goal of this paper is to propose two nonlinear variational models for obtaining a refined motion estimation from an image sequence. Both the proposed models can be considered as a part of a generalized framework for an accurate…

Computer Vision and Pattern Recognition · Computer Science 2024-06-04 Hirak Doshi , N. Uday Kiran

Deep learning has significantly advanced PET image re-construction, achieving remarkable improvements in image quality through direct training on sinogram or image data. Traditional methods often utilize masks for inpainting tasks, but…

Computer Vision and Pattern Recognition · Computer Science 2025-03-12 Bin Huang , Binzhong He , Yanhan Chen , Zhili Liu , Xinyue Wang , Binxuan Li , Qiegen Liu

A two-step shape reconstruction method for diffuse optical tomography (DOT) is presented which uses adjoint fields and level sets. The propagation of near-infrared photons in tissue is modeled by the time-dependent linear transport…

Numerical Analysis · Mathematics 2025-10-20 Oliver Dorn

Linear problems appear in a variety of disciplines and their application for the transmission matrix recovery is one of the most stimulating challenges in biomedical imaging. Its knowledge turns any random media into an optical tool that…

Machine Learning · Statistics 2019-02-05 Daniele Ancora , Luca Leuzzi

A method for automatic computation of parameter derivatives of numerically computed light scattering signals is demonstrated. The finite-element based method is validated in a numerical convergence study, and it is applied to investigate…

Optics · Physics 2013-04-17 S. Burger , L. Zschiedrich , J. Pomplun , F. Schmidt , B. Bodermann

In this paper we develop a framework for parameter estimation in macroscopic pedestrian models using individual trajectories -- microscopic data. We consider a unidirectional flow of pedestrians in a corridor and assume that the velocity…

Analysis of PDEs · Mathematics 2019-03-26 Susana N. Gomes , Andrew M. Stuart , Marie-Therese Wolfram

Reconstruction of structure and parameters of an Ising model from binary samples is a problem of practical importance in a variety of disciplines, ranging from statistical physics and computational biology to image processing and machine…

Statistical Mechanics · Physics 2017-12-27 Andrey Y. Lokhov , Marc Vuffray , Sidhant Misra , Michael Chertkov

We consider a filter stabilization technique with a deconvolution-based indicator function for the simulation of advection dominated advection-diffusion-reaction (ADR) problems with under-refined meshes. The proposed technique has been…

Numerical Analysis · Mathematics 2018-05-04 Kayla Bicol , Annalisa Quaini

The computation of 2-D optical flow by means of regularized pel-recursive algorithms raises a host of issues, which include the treatment of outliers, motion discontinuities and occlusion among other problems. We propose a new approach…

Computer Vision and Pattern Recognition · Computer Science 2016-11-07 Vania V. Estrela , Luis A. Rivera , Paulo C. Beggio , Ricardo T. Lopes

In this work, we investigate the estimation of a parameter $f$ in PDEs using Bayesian procedures, and focus on posterior distributions constructed using Gaussian process priors, and its variational approximation. We establish contraction…

Statistics Theory · Mathematics 2026-01-27 Yuxin Fan , Bangti Jin

Parameter estimation in structural dynamics generally involves inferring the values of physical, geometric, or even customized parameters based on first principles or expert knowledge, which is challenging for complex structural systems. In…

Computational Engineering, Finance, and Science · Computer Science 2025-04-08 Mingyuan Zhou , Haoze Song , Wenjing Ye , Wei Wang , Zhilu Lai

Nonlinear ultrasound imaging leverages harmonic wave generation to enhance contrast and spatial resolution beyond the capabilities of conventional linear techniques. This behavior is commonly modeled by the Westervelt equation, which…

Analysis of PDEs · Mathematics 2026-05-25 Benjamin Rainer , Barbara Kaltenbacher

The identification of states and parameters from noisy measurements of a dynamical system is of great practical significance and has received a lot of attention. Classically, this problem is expressed as optimization over a class of models.…

Perfusion imaging plays a crucial role in acute stroke diagnosis and treatment decision making. Current perfusion analysis relies on deconvolution of the measured signals, an operation that is mathematically ill-conditioned and requires…

Computer Vision and Pattern Recognition · Computer Science 2018-10-12 David Robben , Paul Suetens

Thin film interferometry is a powerful technique for non-invasively measuring liquid film thickness with applications in ophthalmology, but its clinical translation is hindered by the challenges in reconstructing thickness profiles from…

Computer Vision and Pattern Recognition · Computer Science 2025-10-30 Gautam A. Viruthagiri , Arnuv Tandon , Gerald G. Fuller , Vinny Chandran Suja

Recent technical advances lead to the coupling of PET and MRI scanners, enabling to acquire functional and anatomical data simultaneously. In this paper, we propose a tight frame based PET-MRI joint reconstruction model via the joint…

Numerical Analysis · Mathematics 2018-01-08 Jae Kyu Choi , Chenglong Bao , Xiaoqun Zhang

We propose an automated nonlinear model reduction and mesh adaptation framework for rapid and reliable solution of parameterized advection-dominated problems, with emphasis on compressible flows. The key features of our approach are…

Numerical Analysis · Mathematics 2023-08-04 Nicolas Barral , Tommaso Taddei , Ishak Tifouti

We provide a method to identify system parameters of dynamical systems, called ID-ODE -- Inference by Differentiation and Observing Delay Embeddings. In this setting, we are given a dataset of trajectories from a dynamical system with…

Machine Learning · Computer Science 2022-11-17 Alex Tong Lin , Adrian S. Wong , Robert Martin , Stanley J. Osher , Daniel Eckhardt