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Quantum imaging is emerging as a transformative approach for biomedical applications, applying nonclassical properties of light, such as entanglement, squeezing, and quantum correlations, to overcome fundamental limits of conventional…

Analyses based on quantum metrology have shown that the ability to localize the positions of two incoherent point sources can be significantly enhanced through the use of mode sorting. Here we theoretically and experimentally investigate…

We experimentally demonstrate quantum enhanced resolution in confocal fluorescence microscopy exploiting the non-classical photon statistics of single nitrogen-vacancy colour centres in diamond. By developing a general model of…

In single molecule localisation super-resolution microscopy the need for repeated image capture limits the imaging speed, while the size of fluorescence probes limits the possible theoretical localisation resolution. Here, we demonstrated a…

Quantum imaging with undetected photons (QIUP) is a unique method of image acquisition where the photons illuminating the object are not detected. This method relies on quantum interference and spatial correlations between the twin photons…

Quantum Physics · Physics 2024-07-29 Balakrishnan Viswanathan , Gabriela Barreto Lemos , Mayukh Lahiri

Quantum computing has emerged as a transformative paradigm, capable of tackling complex computational problems that are infeasible for classical methods within a practical timeframe. At the core of this advancement lies the concept of…

Quantum Physics · Physics 2025-02-10 Hyunju Lee , Kyungtaek Jun

We calculate the quantum Fisher information (QFI) for estimating, using a circular imaging aperture, the two-dimensional location of a point source against a uniformly bright disk of known center and radius in the ideal photon-counting…

Quantum Physics · Physics 2023-04-12 Sudhakar Prasad

Two-point super-resolution is an important problem in many signal processing applications. In this paper, we aim to establish a resolution theory for two-point super-resolution from a single snapshot. We consider a complex two-point model…

Signal Processing · Electrical Eng. & Systems 2026-05-07 Xiaole He , Ping Liu , Junling Wang

The smallest spot in optical lithography and microscopy is generally limited by diffraction. Quantum lithography, which utilizes interference between groups of N entangled photons, was recently proposed to beat the diffraction limit by a…

Quantum Physics · Physics 2011-12-06 Avi Pe'er , Barak Dayan , Marija Vucelja , Yaron Silberberg , Asher A. Friesem

Optical random scattering is generally considered to be a nuisance of microscopy that limits imaging depth and spatial resolution. Wavefront shaping techniques have recently enabled optical imaging at unprecedented depth, but a remaining…

Optics · Physics 2019-07-26 Donggyu Kim , Dirk R. Englund

The resolution of optical imaging devices is ultimately limited by the diffraction of light. To circumvent this limit, modern super-resolution microscopy techniques employ active interaction with the object by exploiting its optical…

Optics · Physics 2022-01-05 A. A. Pushkina , G. Maltese , J. I. Costa-Filho , P. Patel , A. I. Lvovsky

Super-resolution microscopy has revolutionized the imaging of complex physical and biological systems by surpassing the Abbe diffraction limit. Recent advancements, particularly in single-molecule localization microscopy (SMLM), have pushed…

Optical superresolution microscopy is an important field, where nonlinear optical processes or prior information is used to defeat the classical diffraction limit of light. Quantum correlation microscopy uses photon arrival statistics from…

Optics · Physics 2023-10-13 Jaret J. Vasquez-Lozano , Shuo Li , Andrew D. Greentree

Super-resolution fluorescence microscopy is an important tool in biomedical research for its ability to discern features smaller than the diffraction limit. However, due to its difficult implementation and high cost, the universal…

We suggest a new method for quantum optical control with nanoscale resolution. Our method allows for coherent far-field manipulation of individual quantum systems with spatial selectivity that is not limited by the wavelength of radiation…

Quantum Physics · Physics 2008-03-10 Alexey V. Gorshkov , Liang Jiang , Markus Greiner , Peter Zoller , Mikhail D. Lukin

Fluorescence microscopy is essential in biological and medical research, providing critical insights into cellular structures. However, limited by optical diffraction and background noise, a substantial amount of hidden information is still…

Biological Physics · Physics 2026-04-14 Xiaofeng Zhang , Yongsheng Huang , Jielong Yang , Zhili Wang , Si Chen , Linbo Liu , Xin Ge

Point defects in crystals provide important building blocks for quantum applications. To initialize, control, and read-out their quantum states, an efficient optical interface for addressing defects with photons is required. However,…

Quantum super-resolution involves resolving two sources below the Rayleigh limit using quantum optics. Such a technique would allow high-precision inter-satellite positioning and tracking on communication and navigation constellations. Due…

Quantum Physics · Physics 2024-01-17 Ronakraj K Gosalia , Robert Malaney , Ryan Aguinaldo , Jonathan Green

Optical quantum computing, as well as quantum communication and sensing technology based on quantum correlations are in preparation. These require photodiodes for the detection of about 10^16 photons per second with close to perfect quantum…

Quantum Physics · Physics 2026-02-16 Leif Albers , Jan-Malte Michaelsen , Roman Schnabel

Traceability to the International System of Units (SI) is fundamental to measurement accuracy and reliability. In this study, we demonstrate subnanometer traceability of localization microscopy, establishing a metrological foundation for…

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