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Species complexes are groups of closely related populations exchanging genes through dispersal. We study the dynamics of the structure of species complexes in a class of metapopulation models where demes can exchange genetic material…

Populations and Evolution · Quantitative Biology 2026-03-26 Amaury Lambert , Emmanuel Schertzer , Yannic Wenzel

Motivation: Recombination rates vary considerably at the fine scale within mammalian genomes, with the majority of recombination occurring within hotspots of ~2 kb in width. We present a method for inferring the location of recombination…

Quantitative Methods · Quantitative Biology 2014-03-19 Adam Auton , Simon Myers , Gil McVean

We consider the optimal dynamics in the infinite population evolution models with general symmetric fitness landscape. The search of optimal evolution trajectories are complicated due to sharp transitions (like shock waves) in evolution…

Populations and Evolution · Quantitative Biology 2009-08-18 David B. Saakian , Jose F. Fontanari

The model of interaction between learning and evolutionary optimization is designed and investigated. The evolving population of modeled organisms is considered. The mechanism of the genetic assimilation of the acquired features during a…

Neural and Evolutionary Computing · Computer Science 2014-11-20 Vladimir G. Red'ko

In classical evolutionary theory, genetic variation provides the source of heritable phenotypic variation on which natural selection acts. Against this classical view, several theories have emphasized that developmental variability and…

Populations and Evolution · Quantitative Biology 2011-11-08 Steven A. Frank

In many biological systems, natural selection acts simultaneously on multiple levels of organization. This scenario typically presents an evolutionary conflict between the incentive of individuals to cheat and the collective incentive to…

Populations and Evolution · Quantitative Biology 2022-02-04 Daniel B. Cooney , Yoichiro Mori

Recent research shows that a faulty or sub-optimally operating metabolic network can often be rescued by the targeted removal of enzyme-coding genes--the exact opposite of what traditional gene therapy would suggest. Predictions go as far…

Molecular Networks · Quantitative Biology 2010-03-18 Adilson E. Motter

Cells and microorganisms employ dynamic shape changes to enable steering and avoidance for efficient spatial exploration and collective organization. In contrast, active colloids, their synthetic counterparts, currently lack similar…

Soft Condensed Matter · Physics 2025-01-03 Stefania Ketzetzi , Lorenzo Caprini , Vivien Willems , Laura Alvarez , Hartmut Löwen , Lucio Isa

The ability of biological and artificial collectives to outperform solitary individuals in a wide variety of tasks depends crucially on the efficient processing of social and environmental information at the level of the collective. Here,…

Biological Physics · Physics 2020-10-13 Parisa Rahmani , Fernando Peruani , Pawel Romanczuk

This paper combines the idea of a hierarchical distributed genetic algorithm with different inter-agent partnering strategies. Cascading clusters of sub-populations are built from bottom up, with higher-level sub-populations optimising…

Neural and Evolutionary Computing · Computer Science 2010-07-05 Uwe Aickelin , Larry Bull

Cooperation is beneficial for the species as a whole, but, at the level of an individual, defection pays off. Natural selection is then expected to favor defectors and eliminate cooperation. This prediction is in stark contrast with the…

Populations and Evolution · Quantitative Biology 2013-04-30 Kirill S. Korolev

Social interaction increases significantly the performance of a wide range of cooperative systems. However, evidence that natural swarms limit the number of social connections suggests potentially detrimental consequences of excessive…

Adaptation and Self-Organizing Systems · Physics 2016-09-09 David Mateo , Yoke Kong Kuan , Roland Bouffanais

Intragenomic recombination (crossover) is a very important evolutionary mechanism. The crossover events are not evenly distributed along the natural chromosomes. Monte Carlo simulations revealed that frequency of recombinations decides…

Genomics · Quantitative Biology 2009-01-13 Wojciech Waga , Marta Zawierta , Jakub Kowalski , Stanislaw Cebrat

Living organisms, ecosystems, and social systems are examples of complex systems in which robustness against inclusion of new elements is an essential feature. A recently proposed simple model has revealed a general mechanism by which such…

Adaptation and Self-Organizing Systems · Physics 2018-01-24 Fumiko Ogushi , János Kertész , Kimmo Kaski , Takashi Shimada

We consider a fitness-structured population model with competition and migration between nearest neighbors. Under a combination of large population and rare migration limits we are particularly interested in the asymptotic behavior of the…

Probability · Mathematics 2012-07-20 Anton Bovier , Shi-Dong Wang

The contribution to an organism's phenotype from one genetic locus may depend upon the status of other loci. Such epistatic interactions among loci are now recognized as fundamental to shaping the process of adaptation in evolving…

Populations and Evolution · Quantitative Biology 2012-12-18 Jeremy A. Draghi , Joshua B. Plotkin

Sexual reproduction in Nature requires two sexes, which raises the question why the reproductive scheme did not evolve to have three or more sexes. Here we construct a constrained optimization model based on the communication theory to…

Populations and Evolution · Quantitative Biology 2007-05-23 Bo Deng

Evolution is a dynamic process. The two classical forces of evolution are mutation and selection. Assuming small mutation rates, evolution can be predicted based solely on the fitness differences between phenotypes. Predicting an…

Populations and Evolution · Quantitative Biology 2015-03-23 Benedikt Bauer , Chaitanya S. Gokhale

On rugged fitness landscapes where sign epistasis is common, adaptation can often involve either individually beneficial "uphill" mutations or more complex mutational trajectories involving fitness valleys or plateaus. The dynamics of the…

Populations and Evolution · Quantitative Biology 2015-10-06 Ian E. Ochs , Michael M. Desai

Skip connections made the training of very deep networks possible and have become an indispensable component in a variety of neural architectures. A completely satisfactory explanation for their success remains elusive. Here, we present a…

Neural and Evolutionary Computing · Computer Science 2018-03-06 A. Emin Orhan , Xaq Pitkow
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