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Multiplexed imaging allows multiple cell types to be simultaneously visualised in a single tissue sample, generating unprecedented amounts of spatially-resolved, biological data. In topological data analysis, persistent homology provides…

Quantitative Methods · Quantitative Biology 2025-05-06 Maria Torras-Pérez , Iris H. R. Yoon , Praveen Weeratunga , Ling-Pei Ho , Helen M. Byrne , Ulrike Tillmann , Heather A. Harrington

Persistent homology is a common technique in topological data analysis providing geometrical and topological information about the sample space. All this information, known as topological features, is summarized in persistence diagrams, and…

Methodology · Statistics 2022-04-05 Asael Fabian Martínez

Persistent Homology (PH) is a fundamental tool in computational topology, designed to uncover the intrinsic geometric and topological features of data across multiple scales. Originating within the broader framework of Topological Data…

Algebraic Topology · Mathematics 2025-05-13 Aurelie Jodelle Kemme , Collins Amburo Agyingi

The intrinsic connection between lattice theory and topology is fairly well established, For instance, the collection of open subsets of a topological subspace always forms a distributive lattice. Persistent homology has been one of the…

Rings and Algebras · Mathematics 2014-02-03 Primož Škraba , João Pita Costa

Topological Data Analysis (TDA) is a rising field of computational topology in which the topological structure of a data set can be observed by persistent homology. By considering a sequence of sublevel sets, one obtains a filtration that…

Methodology · Statistics 2020-03-17 Yu-Min Chung , William Cruse , Austin Lawson

Link prediction is an important learning task for graph-structured data. In this paper, we propose a novel topological approach to characterize interactions between two nodes. Our topological feature, based on the extended persistent…

Machine Learning · Computer Science 2021-06-15 Zuoyu Yan , Tengfei Ma , Liangcai Gao , Zhi Tang , Chao Chen

Topological data analysis is an approach to study shape of a data set by means of topology. Its main object of study is the persistence diagram, which represents the topological features of the data set at different spatial resolutions.…

Algebraic Topology · Mathematics 2025-11-05 Azmeer Nordin , Mohd Salmi Md Noorani , Nurulkamal Masseran , Mohd Sabri Ismail , Nur Firyal Roslan

Data quality is crucial for the successful training, generalization and performance of machine learning models. We propose to measure the quality of a subset concerning the dataset it represents, using topological data analysis techniques.…

Algebraic Topology · Mathematics 2024-10-01 Álvaro Torras-Casas , Eduardo Paluzo-Hidalgo , Rocio Gonzalez-Diaz

Over the past two decades, topological data analysis has emerged as a field of applied mathematics with new applications and algorithmic developments appearing rapidly. Two fundamental computations in this field are persistent homology and…

Algebraic Topology · Mathematics 2021-03-02 Gunnar Carlsson , Anjan Dwaraknath , Bradley J. Nelson

In topological data analysis, we want to discern topological and geometric structure of data, and to understand whether or not certain features of data are significant as opposed to simply random noise. While progress has been made on…

Computational Geometry · Computer Science 2020-01-10 So Mang Han , Taylor Okonek , Nikesh Yadav , Xiaojun Zheng

This paper presents a new clustering algorithm for space-time data based on the concepts of topological data analysis and in particular, persistent homology. Employing persistent homology - a flexible mathematical tool from algebraic…

Machine Learning · Statistics 2019-10-28 Umar Islambekov , Yulia Gel

In this paper, we apply persistent entropy, a novel topological statistic, for characterization of images of epithelial tissues. We have found out that persistent entropy is able to summarize topological and geometric information encoded by…

Image and Video Processing · Electrical Eng. & Systems 2021-05-19 N. Atienza , L. M. Escudero , M. J. Jimenez , M. Soriano-Trigueros

The theory of persistence modules is an emerging field of algebraic topology which originated in topological data analysis. In these notes we provide a concise introduction into this field and give an account on some of its interactions…

Algebraic Topology · Mathematics 2021-01-26 Leonid Polterovich , Daniel Rosen , Karina Samvelyan , Jun Zhang

Persistent homology is a mathematical tool used for studying the shape of data by extracting its topological features. It has gained popularity in network science due to its applicability in various network mining problems, including…

Algebraic Topology · Mathematics 2023-06-21 Mehmet Emin Aktas , Thu Nguyen , Rakin Riza , Muhammad Ifte Islam , Esra Akbas

A suitable feature representation that can both preserve the data intrinsic information and reduce data complexity and dimensionality is key to the performance of machine learning models. Deeply rooted in algebraic topology, persistent…

Algebraic Topology · Mathematics 2018-11-02 Chi Seng Pun , Kelin Xia , Si Xian Lee

We start with a simple introduction to topological data analysis where the most popular tool is called a persistent diagram. Briefly, a persistent diagram is a multiset of points in the plane describing the persistence of topological…

Statistics Theory · Mathematics 2017-06-28 Christophe Biscio , Jesper Møller

Persistent homology (PH) is a method used in topological data analysis (TDA) to study qualitative features of data that persist across multiple scales. It is robust to perturbations of input data, independent of dimensions and coordinates,…

Algebraic Topology · Mathematics 2017-09-13 Nina Otter , Mason A. Porter , Ulrike Tillmann , Peter Grindrod , Heather A. Harrington

In real-world systems, the relationships and connections between components are highly complex. Real systems are often described as networks, where nodes represent objects in the system and edges represent relationships or connections…

Algebraic Topology · Mathematics 2024-06-24 Shen Zhang

New representations of tree-structured data objects, using ideas from topological data analysis, enable improved statistical analyses of a population of brain artery trees. A number of representations of each data tree arise from…

Applications · Statistics 2014-11-26 Paul Bendich , J. S. Marron , Ezra Miller , Alex Pieloch , Sean Skwerer

Long lived topological features are distinguished from short lived ones (considered as topological noise) in simplicial complexes constructed from complex networks. A new topological invariant, persistent homology, is determined and…

Mathematical Physics · Physics 2009-11-13 Danijela Horak , Slobodan Maletic , Milan Rajkovic