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Spatial transcriptomics studies are becoming increasingly large and commonplace, necessitating simultaneous analysis of a large number of spatially resolved variables. Correspondingly, a diverse range of methodologies have been proposed to…

Quantitative Methods · Quantitative Biology 2025-09-09 James Boyle , Gregory Hamm , Eleanor Williams , Robin JG Hartman , Magnus Soderburg , Ian Henry , Michael Casey

Topological data analysis provides a multiscale description of the geometry and topology of quantitative data. The persistence landscape is a topological summary that can be easily combined with tools from statistics and machine learning.…

Computational Geometry · Computer Science 2017-07-21 Peter Bubenik , Pawel Dlotko

We present a new tool for data analysis: persistence discrete homology, which is well-suited to analyze filtrations of graphs. In particular, we provide a novel way of representing high-dimensional data as a filtration of graphs using…

Algebraic Topology · Mathematics 2025-06-23 Chris Kapulkin , Nathan Kershaw

Topological methods are very rarely used in structural health monitoring (SHM), or indeed in structural dynamics generally, especially when considering the structure and topology of observed data. Topological methods can provide a way of…

Human-Computer Interaction · Computer Science 2022-09-14 Tristan Gowdridge , Nikolaos Dervilis , Keith Worden

Persistent (co)homology is a central construction in topological data analysis, where it is used to quantify prominence of features in data to produce stable descriptors suitable for downstream analysis. Persistence is challenging to…

Computational Geometry · Computer Science 2024-10-23 Arnur Nigmetov , Dmitriy Morozov

Techniques from computational topology, in particular persistent homology, are becoming increasingly relevant for data analysis. Their stable metrics permit the use of many distance-based data analysis methods, such as multidimensional…

Algebraic Topology · Mathematics 2021-01-20 Bastian Rieck , Filip Sadlo , Heike Leitte

We study a variation of Carlsson and Zomorodian's persistent homology. As an application, we analyze the persistent cellular sheaf cohomology of network coding sheaves on deteriorating networks.

Algebraic Topology · Mathematics 2017-11-07 Karthik Yegnesh

We characterize structures such as monotonicity, convexity, and modality in smooth regression curves using persistent homology. Persistent homology is a key tool in topological data analysis that detects higher-dimensional topological…

Algebraic Topology · Mathematics 2025-10-28 Satish Kumar , Subhra Sankar Dhar

Persistent homology is a powerful tool for characterizing the topology of a data set at various geometric scales. When applied to the description of molecular structures, persistent homology can capture the multiscale geometric features and…

Quantitative Methods · Quantitative Biology 2018-07-31 Zixuan Cang , Guo-Wei Wei

Persistent homology analysis, a recently developed computational method in algebraic topology, is applied to the study of the phase transitions undergone by the so-called XY-mean field model and by the phi^4 lattice model, respectively. For…

TDA (topological data analysis) is a relatively new area of research related to importing classical ideas from topology into the realm of data analysis. Under the umbrella term TDA, there falls, in particular, the notion of persistent…

Algebraic Topology · Mathematics 2019-06-03 Facundo Memoli , Kritika Singhal

Persistent homology is a multiscale method for analyzing the shape of sets and functions from point cloud data arising from an unknown distribution supported on those sets. When the size of the sample is large, direct computation of the…

Topological data analysis involves the statistical characterization of the shape of data. Persistent homology is a primary tool of topological data analysis, which can be used to analyze topological features and perform statistical…

Methodology · Statistics 2023-03-01 Chul Moon , Nicole A. Lazar

Computational topologists recently developed a method, called persistent homology to analyze data presented in terms of similarity or dissimilarity. Indeed, persistent homology studies the evolution of topological features in terms of a…

Quantitative Methods · Quantitative Biology 2017-08-01 Pavel Petrov , Stephen T Rush , Zhichun Zhai , Christine H Lee , Peter T Kim , Giseon Heo

This article aims to study the topological invariant properties encoded in node graph representational embeddings by utilizing tools available in persistent homology. Specifically, given a node embedding representation algorithm, we…

Machine Learning · Computer Science 2021-10-12 Mustafa Hajij , Ghada Zamzmi , Xuanting Cai

The application of network techniques to the analysis of neural data has greatly improved our ability to quantify and describe these rich interacting systems. Among many important contributions, networks have proven useful in identifying…

Quantitative Methods · Quantitative Biology 2018-06-14 Ann E. Sizemore , Jennifer Phillips-Cremins , Robert Ghrist , Danielle S. Bassett

Persistent homology (PH) is a recently developed theory in the field of algebraic topology to study shapes of datasets. It is an effective data analysis tool that is robust to noise and has been widely applied. We demonstrate a general…

Signal Processing · Electrical Eng. & Systems 2020-05-05 Yu-Min Chung , Chuan-Shen Hu , Yu-Lun Lo , Hau-Tieng Wu

Persistent homology provides a robust methodology to infer topological structures from point cloud data. Here we explore the persistent homology of point clouds embedded into a probabilistic setting, exploiting the theory of point…

Probability · Mathematics 2023-08-07 Daniel Spitz , Anna Wienhard

Topological data analysis is a relatively new branch of machine learning that excels in studying high dimensional data, and is theoretically known to be robust against noise. Meanwhile, data objects with mixed numeric and categorical…

Algebraic Topology · Mathematics 2020-06-15 Chengyuan Wu , Carol Anne Hargreaves

Topological data analysis and its main method, persistent homology, provide a toolkit for computing topological information of high-dimensional and noisy data sets. Kernels for one-parameter persistent homology have been established to…

Machine Learning · Computer Science 2019-06-06 René Corbet , Ulderico Fugacci , Michael Kerber , Claudia Landi , Bei Wang