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Secondary structure plays an important role in determining the function of non-coding RNAs. Hence, identifying RNA secondary structures is of great value to research. Computational prediction is a mainstream approach for predicting RNA…

Biomolecules · Quantitative Biology 2021-09-15 Qi Zhao , Zheng Zhao , Xiaoya Fan , Zhengwei Yuan , Qian Mao , Yudong Yao

We analyze growing networks that are built by enhanced redirection. Nodes are sequentially added and each incoming node attaches to a randomly chosen 'target' node with probability 1-r, or to the parent of the target node with probability…

Statistical Mechanics · Physics 2014-07-25 Alan Gabel , P. L. Krapivsky , S. Redner

In post-transcriptional regulation, an mRNA molecule is bound by many proteins and/or miRNAs to modulate its function. To enable combinatorial gene regulation, these binding partners of an RNA must communicate with each other, exhibiting…

Biomolecules · Quantitative Biology 2015-01-26 Yi-Hsuan Lin , Ralf Bundschuh

We provide a general framework for analyzing degree correlations between nodes separated by more than one step (i.e., beyond nearest neighbors) in complex networks. One probability and four conditional probabilities are introduced to fully…

Physics and Society · Physics 2018-06-20 Yuka Fujiki , Taro Takaguchi , Kousuke Yakubo

We provide an analytic expression for the quantity described in the title. Namely, we perform a preferential attachment growth process to generate a scale-free network. At each stage we add a new node with $m$ new links. Let $k$ denote the…

Social and Information Networks · Computer Science 2014-08-13 Michael Small

We present a method for the construction of ensembles of random networks that consist of a single connected component with a given degree distribution. This approach extends the construction toolbox of random networks beyond the…

Disordered Systems and Neural Networks · Physics 2019-04-19 Ido Tishby , Ofer Biham , Eytan Katzav , Reimer Kühn

Recently several minimum free energy (MFE) folding algorithms for predicting the joint structure of two interacting RNA molecules have been proposed. Their folding targets are interaction structures, that can be represented as diagrams with…

Combinatorics · Mathematics 2010-06-22 Thomas J. X. Li , Christian M. Reidys

Quantifying the differences between networks is a challenging and ever-present problem in network science. In recent years a multitude of diverse, ad hoc solutions to this problem have been introduced. Here we propose that simple and…

Complex systems, ranging from soft materials to wireless communication, are often organised as random geometric networks in which nodes and edges evenly fill up the volume of some space. Studying such networks is difficult because they…

Probability · Mathematics 2022-07-19 Ivan Kryven , Rik Versendaal

The primary structure of a ribonucleic acid (RNA) molecule can be represented as a sequence of nucleotides (bases) over the alphabet {A, C, G, U}. The secondary or tertiary structure of an RNA is a set of base pairs which form bonds between…

Data Structures and Algorithms · Computer Science 2015-01-05 Shihyen Chen , Zhuozhi Wang , Kaizhong Zhang

This article discusses the properties of extremes of degree sequences calculated from network data. We introduce the notion of a normalized degree, in order to permit a comparison of degree sequences between networks with differing numbers…

Methodology · Statistics 2012-10-17 Sofia C. Olhede , Patrick J. Wolfe

Many computerized methods for RNA-RNA interaction structure prediction have been developed. Recently, $O(N^6)$ time and $O(N^4)$ space dynamic programming algorithms have become available that compute the partition function of RNA-RNA…

Mathematical Physics · Physics 2010-07-15 Andrew X. Li , Manja Marz , Jing Qin , Christian M. Reidys

We introduce a growing network model in which a new node attaches to a randomly-selected node, as well as to all ancestors of the target node. This mechanism produces a sparse, ultra-small network where the average node degree grows…

Statistical Mechanics · Physics 2009-11-10 P. L. Krapivsky , S. Redner

Entropic measures of complexity are able to quantify the information encoded in complex network structures. Several entropic measures have been proposed in this respect. Here we study the relation between the Shannon entropy and the Von…

Disordered Systems and Neural Networks · Physics 2011-09-30 Kartik Anand , Ginestra Bianconi , Simone Severini

Random network models, constrained to reproduce specific statistical features, are often used to represent and analyze network data and their mathematical descriptions. Chief among them, the configuration model constrains random networks by…

Social and Information Networks · Computer Science 2025-01-28 Laurent Hébert-Dufresne , Jean-Gabriel Young , Alexander Daniels , Alec Kirkley , Antoine Allard

Large RNA molecules often carry multiple functional domains whose spatial arrangement is an important determinant of their function. Pre-mRNA splicing, furthermore, relies on the spatial proximity of the splice junctions that can be…

Quantitative Methods · Quantitative Biology 2013-07-31 Rolf Backofen , Markus Fricke , Manja Marz , Jing Qin , Peter F. Stadler

We present TT2NE, a new algorithm to predict RNA secondary structures with pseudoknots. The method is based on a classification of RNA structures according to their topological genus. TT2NE guarantees to find the minimum free energy…

Biomolecules · Quantitative Biology 2010-10-22 Michael Bon , Henri Orland

The average nearest neighbor degree (ANND) of a node of degree $k$ is widely used to measure dependencies between degrees of neighbor nodes in a network. We formally analyze ANND in undirected random graphs when the graph size tends to…

Probability · Mathematics 2018-01-01 Dong Yao , Pim van der Hoorn , Nelly Litvak

We study the expected adjacency matrix of a uniformly random multigraph with fixed degree sequence $\mathbf{d} \in \mathbb{Z}_+^n$. This matrix arises in a variety of analyses of networked data sets, including modularity-maximization and…

Social and Information Networks · Computer Science 2020-02-10 Philip S. Chodrow

The analytical study of disordered system is usually difficult due to the necessity to perform a quenched average over the disorder. Thus, one may resort to the easier annealed ensemble as an approximation to the quenched system. In the…

Biological Physics · Physics 2009-11-11 Tsunglin Liu , Ralf Bundschuh