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One of the most important processes in the fight against current and future pandemics is the rapid diagnosis and initiation of treatment of viruses in humans. In these times, the development of high-sensitivity tests and diagnostic kits is…

Optics · Physics 2022-12-13 Junfei Wang , Zhenyu Xu , Domna G. Kotsifaki

Infrared spectroscopy is the technique of choice for chemical identification of biomolecules through their vibrational fingerprints. However, infrared light interacts poorly with nanometric size molecules. Here, we exploit the unique…

This study introduces a dual-band plasmonic absorber designed for simultaneous sensing applications in the near-infrared (NIR) and mid-infrared (MIR) regions. The absorber, composed of silver nanostructures on a metal plate with a…

Optics · Physics 2024-11-20 Ayon Sarker , Sajid Muhaimin Choudhury

Visible and infrared photons can be detected with a broadband response via the internal photoeffect. By using plasmonic nanostructures, i.e. nanoantennas, wavelength selectivity can be introduced to such detectors through geometry-dependent…

Developing methods to sense local variations in nearby materials, such as their refractive index and thickness, is important in different fields including chemistry and biomedical applications, among others. Localized surface plasmons…

We study the refractive-index sensing properties of plasmonic nanotubes with a dielectric core and ultra-thin metal shell. The few-nm thin metal shell is described by both the usual Drude model and the nonlocal hydrodynamic model to…

Optics · Physics 2013-05-07 S. Raza , G. Toscano , A. -P. Jauho , N. A. Mortensen , M. Wubs

We demonstrated a biosensing approach which, for the first time, combines the high-sensitivity of whispering gallery modes (WGM) with a metallic nanoparticle based assay. We provided a computational model based on generalized Mie theory to…

Nanophotonic platforms based on surface-enhanced infrared absorbance spectroscopy (SEIRAS) have emerged as an effective tool for molecular detection. Sensitive nanophotonic sensors with robust resonant modes and amplified electromagnetic…

Low-profile patterned plasmonic surfaces are synergized with a broad class of silicon microstructures to greatly enhance near-field nanoscale imaging, sensing, and energy harvesting coupled with far-field free-space detection. This concept…

Optics · Physics 2017-05-02 Hamid T. Chorsi , Ying Zhu , John X. J. Zhang

Label-free biosensors are important tools for clinical diagnostics and for studying biology at the single molecule level. The development of optical label-free sensors has allowed extreme sensitivity, but can expose the biological sample to…

Microplastics are pervasive pollutants that pose threats to the environment and human health. Detecting them reliably represents a crucial step toward finding solutions. While traditional techniques like vibrational and mass spectroscopies…

Instrumentation and Detectors · Physics 2025-05-29 Natalia A. Gutierrez Andrade , Yunfeng Nie , Wendy Meulebroeck , Heidi Ottevaere

The characterization of individual nanoparticles in a liquid constitutes a critical challenge for environmental, material, and biological sciences. To detect nanoparticles, electronic approaches are especially desirable owing to their…

Label-free observation of nanoparticles by far-field optical microscopy is challenging because their ability to scatter or absorb light dramatically diminishes with decreasing size. Surface plasmon resonance (SPR) and localized surface…

Optics · Physics 2020-12-02 Nareg Ohannesian , Ibrahim Misbah , Steven H Lin , Wei-Chuan Shih

Plasmonic nanopores hold a significant promise for molecular sequencing, but their sensitivity and temporal resolution are constrained by limited signal strength and rapid translocation of molecules through the pore. Here we report an…

Optics · Physics 2026-05-12 Nageswar Reddy Sanamreddy , Paolo Vavassori

Spectroscopic analysis of large biomolecules is critical in a number of applications, including medical diagnostics and label-free biosensing. Recently, it has been shown that Raman spectroscopy of proteins can be used to diagnose some…

Understanding light-matter interaction at the nanoscale requires probing the optical properties of matter at the individual nano-absorber level. To this end, we have developed a nanomechanical photothermal sensing platform that can be used…

Optics · Physics 2024-06-07 Kostas Kanellopulos , Robert G. West , Silvan Schmid

Accessing fluid infiltration in nanogranular coatings is an outstanding challenge, of relevance for applications ranging from nanomedicine to catalysis. A sensing platform, allowing to quantify the amount of fluid infiltrated in a…

Interferometric scattering microscopy has been a very promising technology for highly sensitive label-free imaging of a broad spectrum of biological nanoparticles from proteins to viruses in a high-throughput manner. Although it can reveal…

Optics · Physics 2021-08-11 Celalettin Yurdakul , Haonan Zong , Yeran Bai , Ji-Xin Cheng , M. Selim Unlu

Raman spectroscopy is a powerful technique to characterize materials. It probes non-destructively chemical composition, crystallinity, defects, strain and coupling phenomena. However, the Raman response of surfaces or thin films is often…

Wearable biosensors increasingly require continuous and battery-free power sources, but conventional skin-mounted thermoelectric generators are limited by the small temperature differences available in real environments. This work…

Computational Engineering, Finance, and Science · Computer Science 2025-12-10 Hamidreza Moradi , Melika Filvantorkaman