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Recent whole-brain calcium imaging recordings of the nematode C. elegans have demonstrated that neural activity is dominated by dynamics on a low-dimensional manifold that can be clustered according to behavioral states. Despite progress in…

Neurons and Cognition · Quantitative Biology 2020-02-05 Megan Morrison , Charles Fieseler , J. Nathan Kutz

A central problem of neuroscience involves uncovering the principles governing the organization of nervous systems which ensure robustness in brain development. The nematode Caenorhabditis elegans provides us with a model organism for…

Neurons and Cognition · Quantitative Biology 2020-07-01 Anand Pathak , Nivedita Chatterjee , Sitabhra Sinha

Neuro-inspired models and systems have great potential for applications in unconventional computing. Often, the mechanisms of biological neurons are modeled or mimicked in simulated or physical systems in an attempt to harness some of the…

Neural and Evolutionary Computing · Computer Science 2021-10-18 Jørgen Jensen Farner , Håkon Weydahl , Ruben Jahren , Ola Huse Ramstad , Stefano Nichele , Kristine Heiney

The nematode Caenorhabditis elegans is a well-known model organism used to investigate fundamental questions in biology. Motility assays of this small roundworm are designed to study the relationships between genes and behavior. Commonly,…

Computer Vision and Pattern Recognition · Computer Science 2015-05-19 Raphael Sznitman , Manaswi Gupta , Gregory D. Hager , Paulo E. Arratia , Josue Sznitman

The brain has a great capacity for computation and efficient resolution of complex problems, far surpassing modern computers. Neuromorphic engineering seeks to mimic the basic principles of the brain to develop systems capable of achieving…

Motif discovery is a powerful and insightful method to quantify network structures and explore their function. As a case study, we present a comprehensive analysis of regulatory motifs in the connectome of the model organism Caenorhabditis…

Molecular Networks · Quantitative Biology 2024-09-02 Deepak Sharma , Matthias Renz , Philipp Hövel

The nematode Caenorhabditis elegans (C. elegans) serves as an important model organism in a wide variety of biological studies. In this paper we introduce a pipeline for automated analysis of C. elegans imagery for the purpose of studying…

Computer Vision and Pattern Recognition · Computer Science 2020-05-12 Linfeng Wang , Shu Kong , Zachary Pincus , Charless Fowlkes

Inspired by animal navigation strategies, we introduce a novel computational model to navigate and map a space rooted in biologically inspired principles. Animals exhibit extraordinary navigation prowess, harnessing memory, imagination, and…

Robotics · Computer Science 2025-01-07 Daria de Tinguy , Tim Verbelen , Bart Dhoedt

With the rising societal demand for more information-processing capacity with lower power consumption, alternative architectures inspired by the parallelism and robustness of the human brain have recently emerged as possible solutions. In…

Neurons and Cognition · Quantitative Biology 2019-07-02 Emily Toomey , Ken Segall , Karl K. Berggren

A neuromorphic chip that combines CMOS analog spiking neurons and memristive synapses offers a promising solution to brain-inspired computing, as it can provide massive neural network parallelism and density. Previous hybrid analog…

Neural and Evolutionary Computing · Computer Science 2015-06-11 Xinyu Wu , Vishal Saxena , Kehan Zhu

The complex and unique neural network topology of the human brain formed through natural evolution enables it to perform multiple cognitive functions simultaneously. Automated evolutionary mechanisms of biological network structure inspire…

Neural and Evolutionary Computing · Computer Science 2023-09-12 Wenxuan Pan , Feifei Zhao , Zhuoya Zhao , Yi Zeng

This research report introduces ElegansNet, a neural network that mimics real-world neuronal network circuitry, with the goal of better understanding the interplay between connectome topology and deep learning systems. The proposed approach…

Neural and Evolutionary Computing · Computer Science 2024-04-01 Francesco Bardozzo , Andrea Terlizzi , Pietro Liò , Roberto Tagliaferri

Cryogenic neuromorphic systems, inspired by the brains unparalleled efficiency, present a promising paradigm for next generation computing architectures.This work introduces a fully integrated neuromorphic framework that combines…

Emerging Technologies · Computer Science 2025-01-15 Md Mazharul Islam , Julia Steed , Karan Patel , Catherine Schuman , Ahmedullah Aziz

Biological circuits such as neural or gene regulation networks use internal states to map sensory input to an adaptive repertoire of behavior. Characterizing this mapping is a major challenge for systems biology, and though experiments that…

Neurons and Cognition · Quantitative Biology 2022-10-12 Edward D. Lee , Xiaowen Chen , Bryan C. Daniels

In this work, we have proposed a revolutionary neuromorphic computing methodology to implement All-Skyrmion Spiking Neural Network (AS-SNN). Such proposed methodology is based on our finding that skyrmion is a topological stable spin…

Neural and Evolutionary Computing · Computer Science 2017-05-09 Zhezhi He , Deliang Fan

Due to the massive parallel computing capability and outstanding image and signal processing performance, cellular neural network (CNN) is one promising type of non-Boolean computing system that can outperform the traditional digital logic…

Emerging Technologies · Computer Science 2016-09-21 Chenyun Pan , Azad Naeemi

Caenorhabditis elegans (C. elegans) is an excellent model organism because of its short lifespan and high degree of homology with human genes, and it has been widely used in a variety of human health and disease models. However, the…

Computer Vision and Pattern Recognition · Computer Science 2024-11-27 Mengqian Dinga , Jun Liua , Yang Luo , Jinshan Tang

Control is essential to the functioning of any neural system. Indeed, under healthy conditions the brain must be able to continuously maintain a tight functional control between the system's inputs and outputs. One may therefore hypothesise…

Neurons and Cognition · Quantitative Biology 2018-05-29 Emma K. Towlson , Petra E. Vertes , Gang Yan , Yee Lian Chew , Denise S. Walker , William R. Schafer , Albert-Laszlo Barabasi

Spiking Neural Networks are a recent and new neural network design approach that promises tremendous improvements in power efficiency, computation efficiency, and processing latency. They do so by using asynchronous spike-based data flow,…

Computer Vision and Pattern Recognition · Computer Science 2022-06-08 Sambit Mohapatra , Thomas Mesquida , Mona Hodaei , Senthil Yogamani , Heinrich Gotzig , Patrick Mader

Spiking neural networks (SNNs) are receiving increased attention because they mimic synaptic connections in biological systems and produce spike trains, which can be approximated by binary values for computational efficiency. Recently, the…

Neural and Evolutionary Computing · Computer Science 2024-03-26 Nathan Lutes , Venkata Sriram Siddhardh Nadendla , K. Krishnamurthy