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Objective: To treat patients with vascular mild cognitive impairment (VMCI) using TCM, it is necessary to classify the patients into TCM syndrome types and to apply different treatments to different types. We investigate how to properly…

Artificial Intelligence · Computer Science 2016-02-25 Chen Fu , Nevin L. Zhang , Bao Xin Chen , Zhou Rong Chen , Xiang Lan Jin , Rong Juan Guo , Zhi Gang Chen , Yun Ling Zhang

Traditional Chinese Medicine (TCM) is a natural, safe, and effective therapy that has spread and been applied worldwide. The unique TCM diagnosis and treatment system requires a comprehensive analysis of a patient's symptoms hidden in the…

Computation and Language · Computer Science 2022-08-04 Mucheng Ren , Heyan Huang , Yuxiang Zhou , Qianwen Cao , Yuan Bu , Yang Gao

The surge of large language models (LLMs) has driven significant progress in medical applications, including traditional Chinese medicine (TCM). However, current medical LLMs struggle with TCM diagnosis and syndrome differentiation due to…

Computation and Language · Computer Science 2025-10-01 Sibo Wei , Xueping Peng , Yi-Fei Wang , Tao Shen , Jiasheng Si , Weiyu Zhang , Fa Zhu , Athanasios V. Vasilakos , Wenpeng Lu , Xiaoming Wu , Yinglong Wang

Natural medicines, particularly Traditional Chinese Medicine (TCM), are gaining global recognition for their therapeutic potential in addressing human symptoms and diseases. TCM, with its systematic theories and extensive practical…

Computation and Language · Computer Science 2025-05-20 Zhi Liu , Tao Yang , Jing Wang , Yexin Chen , Zhan Gao , Jiaxi Yang , Kui Chen , Bingji Lu , Xiaochen Li , Changyong Luo , Yan Li , Xiaohong Gu , Peng Cao

Syndrome differentiation in Traditional Chinese Medicine (TCM) is the process of understanding and reasoning body condition, which is the essential step and premise of effective treatments. However, due to its complexity and lack of…

Machine Learning · Computer Science 2019-01-23 Zeyuan Wang , Josiah Poon , Shiding Sun , Simon Poon

Traditional Chinese medicine (TCM) tongue diagnosis, while clinically valuable, faces standardization challenges due to subjective interpretation and inconsistent imaging protocols, compounded by the lack of large-scale, annotated datasets…

Image and Video Processing · Electrical Eng. & Systems 2025-07-25 Xuebo Jin , Longfei Gao , Anshuo Tong , Zhengyang Chen , Jianlei Kong , Ning Sun , Huijun Ma , Qiang Wang , Yuting Bai , Tingli Su

Traditional Chinese Medicine (TCM), as an effective alternative medicine, has been receiving increasing attention. In recent years, the rapid development of large language models (LLMs) tailored for TCM has highlighted the urgent need for…

Computation and Language · Computer Science 2025-10-28 Jiacheng Xie , Yang Yu , Ziyang Zhang , Shuai Zeng , Jiaxuan He , Ayush Vasireddy , Xiaoting Tang , Congyu Guo , Lening Zhao , Congcong Jing , Guanghui An , Dong Xu

The recently unprecedented advancements in Large Language Models (LLMs) have propelled the medical community by establishing advanced medical-domain models. However, due to the limited collection of medical datasets, there are only a few…

Computation and Language · Computer Science 2024-06-10 Ping Yu , Kaitao Song , Fengchen He , Ming Chen , Jianfeng Lu

Metaphorical expressions are abundant in Traditional Chinese Medicine (TCM), conveying complex disease mechanisms and holistic health concepts through culturally rich and often abstract terminology. Bridging these metaphors to anatomically…

Computation and Language · Computer Science 2025-03-05 Jiacheng Tang , Nankai Wu , Fan Gao , Chengxiao Dai , Mengyao Zhao , Xinjie Zhao

Traditional Chinese Medicine (TCM), with a history spanning over two millennia, plays a role in global healthcare. However, applying large language models (LLMs) to TCM remains challenging due to its reliance on holistic reasoning, implicit…

Computation and Language · Computer Science 2025-10-21 Jiacheng Xie , Yang Yu , Yibo Chen , Hanyao Zhang , Lening Zhao , Jiaxuan He , Lei Jiang , Xiaoting Tang , Guanghui An , Dong Xu

The explosive growth in the development of Traditional Chinese Medicine (TCM) has resulted in the continued increase in clinical and research data. The lack of standardised terminology, flaws in data quality planning and management of TCM…

Computers and Society · Computer Science 2016-06-09 Wing-Kit Sunny Lam , Tony Sahama , Randike Gajanayake

Traditional Chinese Medicine (TCM) is a holistic medical system with millennia of accumulated clinical experience, playing a vital role in global healthcare-particularly across East Asia. However, the implicit reasoning, diverse textual…

Computation and Language · Computer Science 2025-06-03 Shufeng Kong , Xingru Yang , Yuanyuan Wei , Zijie Wang , Hao Tang , Jiuqi Qin , Shuting Lan , Yingheng Wang , Junwen Bai , Zhuangbin Chen , Zibin Zheng , Caihua Liu , Hao Liang

Traditional Chinese medicine (TCM) relies on natural medical products to treat symptoms and diseases. While clinical data have demonstrated the effectiveness of selected TCM-based treatments, the mechanistic root of how TCM herbs treat…

Molecular Networks · Quantitative Biology 2023-09-28 Xiao Gan , Zixin Shu , Xinyan Wang , Dengying Yan , Jun Li , Shany ofaim , Réka Albert , Xiaodong Li , Baoyan Liu , Xuezhong Zhou , Albert-László Barabási

The emergence of Large Language Models (LLMs) within the Traditional Chinese Medicine (TCM) domain presents an urgent need to assess their clinical application capabilities. However, such evaluations are challenged by the individualized,…

Computation and Language · Computer Science 2025-12-03 Kunning Li , Jianbin Guo , Zhaoyang Shang , Yiqing Liu , Hongmin Du , Lingling Liu , Yuping Zhao , Lifeng Dong

Large language models (LLMs) primarily trained on English texts, often face biases and inaccuracies in Chinese contexts. Their limitations are pronounced in fields like Traditional Chinese Medicine (TCM), where cultural and clinical…

Computation and Language · Computer Science 2025-03-28 Yishen Liu , Shengda Luo , Zishao Zhong , Tongtong Wu , Jianguo Zhang , Peiyao Ou , Yong Liang , Liang Liu , Hudan Pan

Many diseases display heterogeneity in clinical features and their progression, indicative of the existence of disease subtypes. Extracting patterns of disease variable progression for subtypes has tremendous application in medicine, for…

Quantitative Methods · Quantitative Biology 2020-08-04 Sanjukta Krishnagopal

The practice of Traditional Chinese Medicine (TCM) requires profound expertise and extensive clinical experience. While Large Language Models (LLMs) offer significant potential in this domain, current TCM-oriented LLMs suffer two critical…

Computation and Language · Computer Science 2026-01-21 Yehan Yang , Tianhao Ma , Ruotai Li , Xinhan Zheng , Guodong Shan

Traditional Chinese Medicine (TCM) represents a rich repository of ancient medical knowledge that continues to play an important role in modern healthcare. Due to the complexity and breadth of the TCM literature, the integration of AI…

Information Retrieval · Computer Science 2025-06-30 Jinglin He , Yunqi Guo , Lai Kwan Lam , Waikei Leung , Lixing He , Yuanan Jiang , Chi Chiu Wang , Guoliang Xing , Hongkai Chen

This paper details a technical plan for building a clinical case database for Traditional Chinese Medicine (TCM) using web scraping. Leveraging multiple platforms, including 360doc, we gathered over 5,000 TCM clinical cases, performed data…

Computation and Language · Computer Science 2024-11-26 Peng Xu , Hongjin Wu , Jinle Wang , Rongjia Lin , Liwei Tan

Parkinson's disease (PD) is a common neurodegenerative disease with a high degree of heterogeneity in its clinical features, rate of progression, and change of variables over time. In this work, we present a novel data-driven, network-based…

Applications · Statistics 2020-07-01 Sanjukta Krishnagopal , Rainer Von Coelln , Lisa M. Shulman , Michelle Girvan
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