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Mathematical modelling allows us to concisely describe fundamental principles in biology. Analysis of models can help to both explain known phenomena, and predict the existence of new, unseen behaviours. Model analysis is often a complex…

Quantitative Methods · Quantitative Biology 2020-08-13 Mark Blyth , Ludovic Renson , Lucia Marucci

Quantum computing holds great promise for surpassing the limits of classical devices in many fields. Despite impressive developments, however, current research is primarily focused on qubits. At the same time, quantum hardware based on…

Quantum Physics · Physics 2024-10-07 Kevin Mato , Martin Ringbauer , Lukas Burgholzer , Robert Wille

We introduce the Piquasso quantum programming framework, a full-stack open-source software platform for the simulation and programming of photonic quantum computers. Piquasso can be programmed via a high-level Python programming interface…

Quantitative photoacoustic computed tomography (qPACT) is a promising imaging modality for estimating physiological parameters such as blood oxygen saturation. However, developing robust qPACT reconstruction methods remains challenging due…

Medical Physics · Physics 2025-10-07 Refik Mert Cam , Seonyeong Park , Umberto Villa , Mark A. Anastasio

Accurate nuclei detection and classification are fundamental to computational pathology, yet existing approaches are hindered by reliance on detailed expert annotations and insufficient use of tissue context. We present Tissue-Aware Nuclei…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Kesi Xu , Eleni Chiou , Ali Varamesh , Laura Acqualagna , Nasir Rajpoot

As large language models (LLMs) grow in size and deployment scale, quantization has become an essential technique for reducing memory footprint and improving inference efficiency. However, existing quantization toolkits often lack…

Machine Learning · Computer Science 2025-12-01 Dong Liu , Yanxuan Yu

SimOmics is an R package designed to generate realistic, multivariate, and multi-omics synthetic datasets. It is intended for use in benchmarking, method development, and reproducibility in bioinformatics, particularly in the context of…

Genomics · Quantitative Biology 2025-07-15 Kaitao Lai

Computed tomography (CT) is routinely used in clinical practice to evaluate a wide variety of medical conditions. While CT scans provide diagnoses, they also offer the ability to extract quantitative body composition metrics to analyze…

Purpose: The XCAT phantom allows for highly sophisticated multimodality imaging research. It includes a complete set of organs, muscle, bone, soft tissue, while also accounting for age, sex, and body mass index (BMI), which allows phantom…

Motivation: High-throughput omics technologies generate complex datasets with thousands of features that are quantified across multiple experimental conditions, but often suffer from incomplete measurements, missing values and individually…

Quantitative Methods · Quantitative Biology 2025-04-29 Xuan-Tung Trinh , André Abrantes da Costa , David Bouyssié , Adelina Rogowska-Wrzesinska , Veit Schwämmle

Text offers intuitive access to information. This can, in particular, complement the density of numerical time series, thereby allowing improved interactions with time series models to enhance accessibility and decision-making. While the…

Machine Learning · Computer Science 2025-11-10 Felix Divo , Maurice Kraus , Anh Q. Nguyen , Hao Xue , Imran Razzak , Flora D. Salim , Kristian Kersting , Devendra Singh Dhami

Digital Breast Tomosynthesis is an X-ray imaging technique that allows a volumetric reconstruction of the breast, from a small number of low-dose two-dimensional projections. Although it is already used in clinical setting, enhancing the…

Numerical Analysis · Mathematics 2020-07-21 Elena Morotti , Elena Loli Piccolomini

Large language models (LLMs) have proven to be very superior to conventional methods in various tasks. However, their expensive computations and high memory requirements are prohibitive for deployment. Model quantization is an effective…

Artificial Intelligence · Computer Science 2024-03-06 Hanlin Tang , Yifu Sun , Decheng Wu , Kai Liu , Jianchen Zhu , Zhanhui Kang

Quantum state tomography is a fundamental task in quantum computing, involving the reconstruction of an unknown quantum state from measurement outcomes. Although essential, it is typically introduced at the graduate level due to its…

Quantum Physics · Physics 2025-07-14 Mohammad Aamir Sohail , Ranga Sudharshan , S. Sandeep Pradhan , Arvind Rao

TOPCAT, the Tool for OPerations on Catalogues And Tables, is an interactive desktop application for retrieval, analysis and manipulation of tabular data, offering a powerful and flexible range of interactive visualization options amongst…

Instrumentation and Methods for Astrophysics · Physics 2017-07-10 Mark Taylor

We sought to develop a quantitative tool to quickly determine relative differences in MRI volumes both within and between large MR imaging cohorts (such as available in The Cancer Imaging Archive (TCIA)), in order to help determine the…

Image and Video Processing · Electrical Eng. & Systems 2021-06-09 Amir Reza Sadri , Andrew Janowczyk , Ren Zou , Ruchika Verma , Niha Beig , Jacob Antunes , Anant Madabhushi , Pallavi Tiwari , Satish E. Viswanath

Quantization is a technique for creating efficient Deep Neural Networks (DNNs), which involves performing computations and storing tensors at lower bit-widths than f32 floating point precision. Quantization reduces model size and inference…

Machine Learning · Computer Science 2023-10-02 Eliska Kloberdanz , Wei Le

Face Image Quality Assessment (FIQA) aims to predict the utility of a face image for face recognition (FR) systems. State-of-the-art FIQA methods mainly rely on convolutional neural networks (CNNs), leaving the potential of Vision…

Computer Vision and Pattern Recognition · Computer Science 2025-08-25 Andrea Atzori , Fadi Boutros , Naser Damer

SeQuant is an open-source library for symbolic algebra of tensors over commutative (scalar) and non-commutative (operator) rings. The key innovation supporting most of its functionality is a graph-theoretic tensor network (TN) canonicalizer…

Mathematical Software · Computer Science 2026-04-20 Bimal Gaudel , Robert G. Adam , Ajay Melekamburath , Conner Masteran , Nakul Teke , Azam Besharatnik , Andreas Köhn , Edward F. Valeev

Recent advances in quantum computers and simulators are steadily leading us towards full-scale quantum computing devices. Due to the fact that debugging is necessary to create any computing device, quantum tomography (QT) is a critical…

Quantum Physics · Physics 2021-10-12 B. I. Bantysh , A. Yu. Chernyavskiy , Yu. I. Bogdanov