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Feedback in sensory biochemical networks can give rise to bifurcations in cells' behavioral response. These bifurcations share many properties with thermodynamic critical points. Evidence suggests that biological systems may operate near…

Biological Physics · Physics 2020-12-04 Michael Vennettilli , Amir Erez , Andrew Mugler

Social interaction between microbes can be described at many levels of details, ranging from the biochemistry of cell-cell interactions to the ecological dynamics of populations. Choosing the best level to model microbial communities…

Populations and Evolution · Quantitative Biology 2020-09-09 Chen Liao , Tong Wang , Sergei Maslov , Joao B. Xavier

Signal transduction within biological cells is governed by networks of interacting proteins. Communication between these proteins is mediated by signaling molecules which bind to receptors and induce stochastic transitions between different…

Molecular Networks · Quantitative Biology 2017-04-05 Gonzalo Hernandez-Hernandez , Jesse Myers , Enric Alvarez-Lacalle , Yohannes Shiferaw

Information delivery using chemical molecules is an integral part of biology at multiple distance scales and has attracted recent interest in bioengineering and communication. The collective signal strength at the receiver (i.e., the…

Information Theory · Computer Science 2016-08-04 Yansha Deng , Adam Noel , Weisi Guo , Arumugam Nallanathan , Maged Elkashlan

The increasing global push for carbon reduction highlights the importance of integrating renewable energy into the supply chain of cellular networks. However, due to the stochastic nature of renewable energy generation and the uneven load…

Signal Processing · Electrical Eng. & Systems 2026-01-21 Yuxi Zhao , Vicente Casares-Giner , Vicent Pla , Luis Guijarro , Iztok Humar , Yi Zhong , Xiaohu Ge

Efficient energy transduction is one driver of evolution; and thus understanding biomolecular energy transduction is crucial to understanding living organisms. As an energy-orientated modelling methodology, bond graphs provide a useful…

Molecular Networks · Quantitative Biology 2018-06-11 Peter J. Gawthrop , Edmund J. Crampin

Vibrationally inelastic electron transport through a molecular bridge that is connected to two leads is investigated. The study is based on a generic model of vibrational excitation in resonant transmission of electrons through a molecular…

Mesoscale and Nanoscale Physics · Physics 2009-11-10 Martin Cizek , Michael Thoss , Wolfgang Domcke

We model hypothetical bio-dispersal within a single Galactic region using the stochastic infection dynamics process, which is inspired by these local properties of life dispersal on Earth. We split the population of stellar systems into…

Earth and Planetary Astrophysics · Physics 2022-04-27 Andjelka B. Kovacevic

Biological functionality of cellular aggregates is largely influenced by the activity and displacements of individual constituent cells. From a theoretical perspective this activity can be characterized by hydrodynamic transport…

Soft Condensed Matter · Physics 2025-07-31 Subhadip Chakraborti , Vasily Zaburdaev

Information theory provides powerful tools for understanding communication systems. This analysis can be applied to intercellular signal transduction, which is a means of chemical communication among cells and microbes. We discuss how to…

Quantitative Methods · Quantitative Biology 2016-11-15 Andrew W. Eckford , Kenneth A. Loparo , Peter J. Thomas

Simplified stochastic models are widely used in the study of frequency-resolved noise propagation in biochemical reaction networks, a common measure being the coherence between random fluctuations in molecule number trajectories. Such…

Molecular Networks · Quantitative Biology 2025-11-03 Juan David Marmolejo Lozano , Nikola Popovic , Ramon Grima

Inelastic electron transfer being regarded as one of the potential mechanisms to explain the odorant recognition in the atomic-scale processes is still a matter of intense debate. Here, we propose multiphonon processes of electrons transfer…

Biological Physics · Physics 2021-08-02 Shu-Quan Zhang , Yu Cui , Xue-Wei Li , Yong Sun , Zi-Wu Wang

Cell spreading is investigated at various scales in order to understand motility of living cells which is essential for a range of physiological activities in higher organisms as well as in microbes. At a microscopic scale, it has been seen…

Cell Behavior · Quantitative Biology 2009-11-13 A. Bhattacharyay

Energy transfer during molecular collisions on metal surfaces plays a pivotal role in a host of critical interfacial processes. Despite significant efforts, our understanding of relevant energy transfer mechanisms, even in an…

Chemical Physics · Physics 2025-03-24 Gang Meng , Bin Jiang

The cytoskeleton in eukaryotic cells plays several crucial roles. In terms of intracellular transport, motor proteins use the cytoskeletal filaments as a backbone along which they can actively transport biological cargos such as vesicles…

Biological Physics · Physics 2020-06-20 Adélaïde Raguin , Norbert Kern , Andrea Parmeggiani

Cellular bioelectricity describes the biological phenomenon in which cells in living tissue generate and maintain patterns of voltage gradients induced by differing concentrations of charged ions. A growing body of research suggests that…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-09-27 Seth Gilbert , James Maguire , Calvin Newport

The prospect of new biological and industrial applications that require communication in micro-scale, encourages research on the design of bio-compatible communication networks using networking primitives already available in nature. One of…

Information Theory · Computer Science 2012-05-23 Arash Einolghozati , Mohsen Sardari , Ahmad Beirami , Faramarz Fekri

Fluctuations in biochemical networks, e.g., in a living cell, have a complex origin that precludes a description of such systems in terms of bipartite or multipartite processes, as is usually done in the framework of stochastic and/or…

Statistical Mechanics · Physics 2020-01-29 R. Chétrite , M. L. Rosinberg , T. Sagawa , G. Tarjus

The inherent stochasticity of cellular processes leads to significant cell-to-cell variation in protein abundance. Although this noise has already been characterized and modeled, its broader implications and significance remain unclear. In…

Biological Physics · Physics 2023-07-10 Teresa W. Lo , Han Kyou James Choi , Dean Huang , Paul A. Wiggins

Inter and intra-cellular signaling are essential for individual cells to execute various physiological tasks and accurately respond to changes in their environment. Signaling is carried out via diffusible molecules, the transport of which…

Soft Condensed Matter · Physics 2020-10-13 Sumantra Sarkar , Sandeep Choubey