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Intercellular signaling has an important role in organism development, but not all communication occurs using the same mechanism. Here, we analyze the energy efficiency of intercellular signaling by two canonical mechanisms: diffusion of…

Quantitative Methods · Quantitative Biology 2022-11-30 Hyunjoong Kim , Yoichiro Mori , Joshua B. Plotkin

It is shown that at low temperatures and moderate electron dephasing the electron transmission function reveales a structure containing information about donor/acceptor sites effectively participating in the electron transfer (ET) processes…

Biological Physics · Physics 2007-05-23 Natalya A. Zimbovskaya

A biofilm is a microbial city. It consists of bacteria embedded in an extracellular polymeric substance (EPS) that functions as a protective barrier. Quorum sensing (QS) is a method of bacterial communication, where autoinducers (AIs)…

Signal Processing · Electrical Eng. & Systems 2024-08-15 Yanahan Paramalingam , Hamidreza Arjmandi , Freya Harrison , Tara Schiller , Adam Noel

In the work the process of the energy transfer in the cell microtubules is simulated. A system of tryptophans connected by Coulomb dipole-dipole interaction is discussed as the energy carriers. The work models the conditions under which the…

Biological Physics · Physics 2023-03-08 Sergey Ehduardovich Shirmovsky

We present a stochastic formalism for signal transduction processes in bacterial two-component system. Using elementary mass action kinetics, the proposed model takes care of signal transduction in terms of phosphotransfer mechanism between…

Subcellular Processes · Quantitative Biology 2014-03-26 Alok Kumar Maity , Arnab Bandyopadhyay , Pinaki Chaudhury , Suman K Banik

The biological world, especially its majority microbial component, is strongly interacting and may be dominated by collective effects. In this review, we provide a brief introduction for statistical physicists of the way in which living…

Populations and Evolution · Quantitative Biology 2015-05-20 Nicholas Chia , Nigel Goldenfeld

A closer look at nature has recently brought more interest in exploring and utilizing intra-body communication networks composed of cells as intrinsic, perfectly biocompatible infrastructures to deliver therapeutics. Naturally occurring…

Signal Processing · Electrical Eng. & Systems 2022-07-06 Hamid Khoshfekr Rudsari , Mohammad Zoofaghari , Mladen Veletic , Jacob Bergsland , Ilangko Balasingham

Cells use temporal dynamical patterns to transmit information via signaling pathways. As optimality with respect to the environment plays a fundamental role in biological systems, organisms have evolved optimal ways to transmit information.…

Biological Physics · Physics 2016-12-21 Yoshihiko Hasegawa

Exchange of biochemical substances is essential way in establishing communication between bacterial cells. It is noticeable that all phases of the process are heavily influenced by perturbations of either internal or external parameters.…

Chaotic Dynamics · Physics 2010-08-18 Igor Balaz , Dragutin T. Mihailovic

Filamentous cable bacteria exhibit unprecedented long-range biological electron transport, which takes place in a parallel fibre structure that shows an extraordinary electrical conductivity for a biological material. Still, the underlying…

Currently, molecular tunnel junctions are recognized as important active elements of various nanodevices. This gives a strong motivation to study physical mechanisms controlling electron transport through molecules. Electron motion through…

Mesoscale and Nanoscale Physics · Physics 2013-01-24 Natalya A. Zimbovskaya

Cancer invasion and metastasis depend on angiogenesis. The cellular processes (growth, migration, and apoptosis) that occur during angiogenesis are tightly regulated by signaling molecules. Thus, understanding how cells synthesize multiple…

Molecular Networks · Quantitative Biology 2008-03-05 Amy L. Bauer , Trachette L. Jackson , Yi Jiang , Thimo Rohlf

Although continuous advances in theoretical modelling of Molecular Communications (MC) are observed, there is still an insuperable gap between theory and experimental testbeds, especially at the microscale. In this paper, the development of…

Biological cells embedded in fibrous matrices have been observed to form inter-cellular bands of dense and aligned fibers, through which they mechanically interact over long distances. Such matrix-mediated cellular interactions have been…

Biological Physics · Physics 2018-11-14 Ran S Sopher , Hanan Tokash , Sari Natan , Mirit Sharabi , Ortal Shelah , Oren Tchaicheeyan , Ayelet Lesman

Cells can be considered as systems that utilize changes in thermodynamic entropy as information. Therefore, they serve as useful models for investigating the relationships between entropy production and information transmission, i.e.,…

Molecular Networks · Quantitative Biology 2017-03-09 Tatsuaki Tsuruyama

Studies on the role of fluctuations in signal propagation and on gene regulation in monoclonal bacterial population have been extensively pursued based on the machinery of two-component system. The bacterial two-component system shows noise…

Molecular Networks · Quantitative Biology 2017-01-10 Tarunendu Mapder , Sudip Chattopadhyay , Suman K Banik

Bacteria possess diverse mechanisms to regulate their motility in response to environmental and physiological signals, enabling them to navigate complex habitats and adapt their behavior. Among these mechanisms, interspecies recognition…

Populations and Evolution · Quantitative Biology 2025-12-01 Mattia Mattei , David Soriano Paños , Mahantesh Halappanavar , Alex Arenas

Biological cells sense and respond to mechanical forces, but how such a mechanosensing proccess takes place in a nonlinear inhomogeneous fibrous matrix remains unknown. We show that cells in a fibrous matrix induce deformation fields that…

Biological Physics · Physics 2015-06-10 Jacob Notbohm , Ayelet Lesman , Phoebus Rosakis , David A. Tirrell , Guruswami Ravichandran

Living cells presumably employ optimized information transfer methods, enabling efficient communication even in noisy environments. As expected, the efficiency of chemical communications between cells depends on the properties of the…

Biological functions in living cells are controlled by protein interaction and genetic networks. These molecular networks should be dynamically stable against various fluctuations which are inevitable in the living world. In this paper, we…

Molecular Networks · Quantitative Biology 2009-11-13 Yuping Zhang , Minping Qian , Qi Ouyang , Minghua Deng , Fangting Li , Chao Tang