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We investigate the dependence of the displacements of a molecular motor embedded inside a glassy material on its folding characteristic time. We observe two different time regimes. For slow foldings (regime I) the diffusion evolves very…

Properties of transport of molecular motors are investigated. A simplified model based on the concept of Brownian ratchets is applied. We analyze a stochastic equation of motion by means of numerical methods. The transport is systematically…

Statistical Mechanics · Physics 2011-12-07 Lukasz Machura , Marcin Kostur , Jerzy Luczka

Tracking experiments in dense biological tissues reveal a diversity of sources f or local energy injection at the cell scale. The effect of cell motility has been largely studied, but much less is known abo ut the effect of the observed…

Soft Condensed Matter · Physics 2017-11-29 Elsen Tjhung , Ludovic Berthier

Myosin motor proteins drive vigorous steady-state fluctuations in the actin cytoskeleton of cells. Endogenous embedded semiflexible filaments such as microtubules, or added filaments such as single-walled carbon nanotubes are used as novel…

Biological Physics · Physics 2016-06-21 J. Gladrow , N. Fakhri , F. C. MacKintosh , C. F. Schmidt , C. P. Broedersz

We theoretically consider the carrier density tuned (apparent) two-dimensional (2D) metal-insulator-transition (MIT) in semiconductor heterostructure-based 2D carrier systems as arising from a classical percolation phenomenon in the…

Mesoscale and Nanoscale Physics · Physics 2013-10-15 S. Das Sarma , E. H. Hwang , Qiuzi Li

Diffusion processes are widespread in biological and chemical systems, where they play a fundamental role in the exchange of substances at the cellular level and in determining the rate of chemical reactions. Recently, the classical picture…

Soft Condensed Matter · Physics 2015-09-16 Roberto Cerbino , Yifei Sun , Aleksandar Donev , Alberto Vailati

We study the transport properties of particles draining from a silo using imaging and direct particle tracking. The particle displacements show a universal transition from super-diffusion to normal diffusion, as a function of the distance…

Soft Condensed Matter · Physics 2007-05-23 Jaehyuk Choi , A. Kudrolli , R. R. Rosales , Martin Z. Bazant

We introduce a new model to study the oscillations of opposite flows sharing a common bottleneck and moving on two Totally Asymmetric Simple Exclusion Process (TASEP) lanes. We provide a theoretical analysis of the phase diagram, valid when…

Statistical Mechanics · Physics 2012-06-15 Asja Jelić , Cécile Appert-Rolland , Ludger Santen

We consider in this paper a solvable model for the motion of molecular motors. Based on the averaging principle, we reduce the problem to a diffusion process on a graph. We then calculate the effective speed of transportation of these…

Probability · Mathematics 2013-06-11 Mark Freidlin , Wenqing Hu

In this work, a two-dimensional time-fractional subdiffusion model is developed to investigate the underlying transport phenomena evolving in a binary medium comprised of two sub-domains occupied by homogeneous material. We utilise an…

Numerical Analysis · Mathematics 2021-02-05 Libo Feng , Ian Turner , Patrick Perre , Kevin Burrage

From footpaths to flight routes, human mobility networks facilitate the spread of communicable diseases. Control and elimination efforts depend on characterizing these networks in terms of connections and flux rates of individuals between…

Populations and Evolution · Quantitative Biology 2016-01-29 Kyle B Gustafson , Basil S. Bayati , Philip A. Eckhoff

Vibrationally inelastic electron transport through a flexible molecular junction is investigated. The study is based on a mechanistic model for a biphenyl molecule between two metal electrodes. Employing methods from electron-molecule…

Mesoscale and Nanoscale Physics · Physics 2023-07-26 Martin Cizek , Michael Thoss , Wolfgang Domcke

The mechanics of cells is strongly affected by molecular motors that generate forces in the cellular cytoskeleton. We develop a model for cytoskeletal networks driven out of equilibrium by molecular motors exerting transient contractile…

Soft Condensed Matter · Physics 2009-11-13 Fred C. MacKintosh , Alex J. Levine

In many biological systems, the movement of individual agents is commonly characterized as having multiple qualitatively distinct behaviors that arise from various biophysical states. This is true for vesicles in intracellular transport,…

Subcellular Processes · Quantitative Biology 2022-07-25 Maria-Veronica Ciocanel , John Fricks , Peter R. Kramer , Scott A. McKinley

We analyze theoretically the effects of excluded-volume interactions between motors on the dynamics of a cargo driven by multiple motors. The model considered shares many commons with other recently proposed in the literature, with the…

Biological Physics · Physics 2010-12-15 Sebastian Bouzat , Fernando Falo

We show that the correlated stochastic fluctuation of the friction coefficient can give rise to long-range directional motion of a particle undergoing Brownian random walk in a constant periodic energy potential landscape. The occurrence of…

Soft Condensed Matter · Physics 2009-11-07 Lorenzo Marrucci , Domenico Paparo , Markus Kreuzer

While ubiquitous, energy redistribution remains a poorly understood facet of the nonequilibrium thermodynamics of biomolecules. At the molecular level, finite-size effects, pronounced nonlinearities, and ballistic processes produce behavior…

Biological Physics · Physics 2019-11-15 Justin E. Elenewski , Kirill A. Velizhanin , Michael Zwolak

By considering subexponential contributions in large deviation theory, we determine the fine structure in the probability distribution of the observable displacement of a bead coupled to a molecular motor. More generally, for any stochastic…

Statistical Mechanics · Physics 2014-07-11 Patrick Pietzonka , Eva Zimmermann , Udo Seifert

The activity of biological cells is primarily based on chemical reactions and typically modeled as a reaction-diffusion system. Cells are, however, highly crowded with macromolecules, including a variety of molecular machines such as…

Biological Physics · Physics 2018-11-02 Yuichi Togashi

Various charge migration mechanisms in the DNA are studied within the framework of the Peyrard-Bishop-Holstein model which has been widely used to address charge dynamics in this macromolecule. To analyze these mechanisms we consider…

Biological Physics · Physics 2022-09-14 R. P. A. Lima , A. V. Malyshev
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