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Inside cells, cargos such as vesicles and organelles are transported by molecular motors to their correct locations via active motion on cytoskeletal tracks and passive, Brownian diffusion. During the transportation of cargos, motor-cargo…

Soft Condensed Matter · Physics 2018-04-10 Supravat Dey , Kevin Ching , Moumita Das

We exactly calculate two-point spatial correlation functions in steady state in a broad class of conserved-mass transport processes, which are governed by chipping, diffusion and coalescence of masses. We find that the spatial correlations…

Statistical Mechanics · Physics 2016-06-28 Arghya Das , Sayani Chatterjee , Punyabrata Pradhan

The movement of motor particles consisting of one or several molecular motors bound to a cargo particle is studied theoretically. The particles move on patterns of immobilized filaments. Several patterns are described for which the motor…

Statistical Mechanics · Physics 2009-11-11 Stefan Klumpp , Reinhard Lipowsky

Intracellular transport is essential for maintaining proper cellular function in most eukaryotic cells, with perturbations in active transport resulting in several types of disease. Efficient delivery of critical cargos to specific…

Biological Physics · Physics 2016-08-16 David Ando , Nickolay Korabel , Kerwyn Casey Huang , Ajay Gopinathan

Active filaments, such as microtubules with attached cargo-carrying motor proteins, are important dynamic structures for fluid transport in and around living cells. The mathematical models of active filaments appearing in the literature…

Fluid Dynamics · Physics 2025-08-19 Ilteber R. Ozdemir , Bethany Clarke , Yongyun Hwang , Eric E. Keaveny

In this paper, we derive an effective model for transport processes in periodically perforated elastic media, taking into account, e.g., cyclic elastic deformations as they occur in lung tissue due to respiratory movement. The underlying…

Analysis of PDEs · Mathematics 2022-06-15 Jonas Knoch , Markus Gahn , Maria Neuss-Radu , Nicolas Neuß

We consider the diffusion-advection problem in two simple cellular flow models (often invoked as examples for subdiffusive tracer's motion) and concentrate on the intermediate time range, in which the tracer's motion indeed may show…

Fluid Dynamics · Physics 2016-09-28 Patrick Pöschke , Igor M. Sokolov , Alexander A. Nepomnyashchy , Michael A. Zaks

By event-driven molecular dynamics simulations we investigate magneto-transport in a two-dimensional model with randomly distributed scatterers close to the field-induced localization transition. This transition is generated by percolating…

Mesoscale and Nanoscale Physics · Physics 2015-12-14 Walter Schirmacher , Benedikt Fuchs , Felix Höfling , Thomas Franosch

Molecular signalling in living cells occurs at low copy numbers and is thereby inherently limited by the noise imposed by thermal diffusion. The precision at which biochemical receptors can count signalling molecules is intimately related…

Statistical Mechanics · Physics 2016-09-26 Aljaz Godec , Ralf Metzler

Enhanced colloidal transport beyond the limit imposed by diffusion is usually achieved through external fields. Here, we demonstrate the ballistic transport of a colloidal sphere using internal sources of energy provided by an attached…

Soft Condensed Matter · Physics 2017-01-12 Raj Kumar Manna , P. B. Sunil Kumar , R. Adhikari

Active fluids operate by constantly dissipating energy at the particle level to perform a directed motion, yielding dynamics and phases without any equilibrium equivalent. The emerging behaviors have been studied extensively, yet…

Statistical Mechanics · Physics 2020-02-03 Étienne Fodor , Takahiro Nemoto , Suriyanarayanan Vaikuntanathan

While it is commonly observed that the shape dynamics of mammalian cells can undergo large random fluctuations, theoretical models aiming at capturing cell mechanics often focus on the deterministic part of the motion. In this paper, we…

Biological Physics · Physics 2021-04-07 Vikram Deshpande , Antonio DeSimone , Robert McMeeking , Pierre Recho

With the use of the "two-fluid model", we discuss anomalous diffusion induced by active force dipoles in viscoelastic media. Active force dipoles, such as proteins and bacteria, generate non-thermal fluctuating flows that lead to a…

Soft Condensed Matter · Physics 2017-03-29 Kento Yasuda , Ryuichi Okamoto , Shigeyuki Komura

Many biological processes involve the action of molecular motors that interact with the cell cytoskeleton. Some processes, such as the transport of cargoes is achieved mainly by the action of individual motors. Other, such as cell motility…

Biological Physics · Physics 2011-03-25 Oded Farago , Anne Bernheim-Groswasser

We study dynamical fluctuations in overdamped diffusion processes driven by time periodic forces. This is done by studying fluctuation functionals (rate functions from large deviation theory), of fluctuations around the non-equilibrium…

Statistical Mechanics · Physics 2010-03-18 Navinder Singh , Bram Wynants

Aims: We aim to determine the effect of converging flows on the evolution of a bipolar magnetic region (BMR), and to investigate the role of these inflows in the generation of poloidal flux. We also discuss whether the flux dispersal due to…

Solar and Stellar Astrophysics · Physics 2016-01-27 David Martin-Belda , Robert H. Cameron

Intercellular signaling has an important role in organism development, but not all communication occurs using the same mechanism. Here, we analyze the energy efficiency of intercellular signaling by two canonical mechanisms: diffusion of…

Quantitative Methods · Quantitative Biology 2022-11-30 Hyunjoong Kim , Yoichiro Mori , Joshua B. Plotkin

Dry friction has been proposed as a rectifying mechanism allowing mass transport over a vibrating surface, even when vibrations are horizontal and unbiased. It has been suggested that the drift velocity will always saturate when the energy…

Soft Condensed Matter · Physics 2024-10-16 Martin Maza-Cuello , Diego Maza

The cytoskeleton is an important subsystem of cells that is involved for example in cell division and locomotion. It consists of filaments that are cross-linked by molecular motors that can induce relative sliding between filaments and…

Statistical Mechanics · Physics 2007-08-08 P. K. Mohanty , K. Kruse

In cells, organelles and vesicles are usually transported by cooperation of several motor proteins, including plus-end directed motor kinesin and minus-end directed motor dynein. Many biophysical models have been constructed to understand…

Chemical Physics · Physics 2015-05-19 Yunxin Zhang