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In the critical beta-splitting model of a random $n$-leaf binary tree, leaf-sets are recursively split into subsets, and a set of $m$ leaves is split into subsets containing $i$ and $m-i$ leaves with probabilities proportional to…

Probability · Mathematics 2024-09-09 David Aldous , Boris Pittel

Rooted bifurcating trees are mathematical objects used to model evolutionary relationships and arise naturally in both coalescent theory and phylogenetics. Recent numerical representations of tree topologies, known as F-matrices, allow for…

Phylogenetic invariants are not the only constraints on site-pattern frequency vectors for phylogenetic trees. A mutation matrix, by its definition, is the exponential of a matrix with non-negative off-diagonal entries; this positivity…

Populations and Evolution · Quantitative Biology 2008-05-29 Frederick A. Matsen

While Flory theories provide an extremely useful framework for understanding the behavior of interacting, randomly branching polymers, the approach is inherently limited. Here we use a combination of scaling arguments and computer…

Statistical Mechanics · Physics 2017-01-18 Angelo Rosa , Ralf Everaers

The Fr\'{e}chet mean is a fundamental notion of central tendency defined as a minimizer of a sum of squared distances in a general metric space. In this paper, we study Fr\'{e}chet means in tropical geometry -- a piecewise linear,…

Optimization and Control · Mathematics 2026-03-20 Kamillo Ferry , Bo Lin , Carlos Améndola , Anthea Monod , Ruriko Yoshida

We consider a probability distribution on the set of Boolean functions in n variables which is induced by random Boolean expressions. Such an expression is a random rooted plane tree where the internal vertices are labelled with connectives…

Combinatorics · Mathematics 2015-09-28 Antoine Genitrini , Bernhard Gittenberger , Veronika Kraus , Cécile Mailler

We consider so-called simple families of labelled trees, which contain, e.g., ordered, unordered, binary and cyclic labelled trees as special instances, and study the global and local behaviour of the number of inversions. In particular we…

Combinatorics · Mathematics 2011-01-26 Alois Panholzer , Georg Seitz

Consider a tree $T=(V,E)$ with root $\circ$ and edge length function $\ell:E\to\mathbb{R}_+$. The phylogenetic covariance matrix of $T$ is the matrix $C$ with rows and columns indexed by $L$, the leaf set of $T$, with entries…

Populations and Evolution · Quantitative Biology 2025-09-22 Sean P. Svihla , Manuel E. Lladser

In the critical beta-splitting model of a random $n$-leaf rooted tree, clades are recursively (from the root) split into sub-clades, and a clade of $m$ leaves is split into sub-clades containing $i$ and $m-i$ leaves with probabilities…

Probability · Mathematics 2025-04-21 David J. Aldous , Svante Janson

Phylogenetic networks are increasingly used in evolutionary biology to represent the history of species that have undergone reticulate events such as horizontal gene transfer, hybrid speciation and recombination. One of the most fundamental…

Populations and Evolution · Quantitative Biology 2016-10-07 Philippe Gambette , Leo van Iersel , Steven Kelk , Fabio Pardi , Celine Scornavacca

Understanding the patterns and processes of diversification of life in the planet is a key challenge of science. The Tree of Life represents such diversification processes through the evolutionary relationships among the different taxa, and…

Populations and Evolution · Quantitative Biology 2011-06-16 E. Alejandro Herrada , Claudio J. Tessone , Konstantin Klemm , Victor M. Eguiluz , Emilio Hernandez-Garcia , Carlos M. Duarte

Phylogenetic networks are a generalization of phylogenetic trees that allow for representation of reticulate evolution. Recently, a space of unrooted phylogenetic networks was introduced, where such a network is a connected graph in which…

Populations and Evolution · Quantitative Biology 2017-03-09 Andrew Francis , Katharina Huber , Vincent Moulton , Taoyang Wu

Fr\'echet regression extends the principles of linear regression to accommodate responses valued in generic metric spaces. While this approach has primarily focused on exploring relationships between Euclidean predictors and non-Euclidean…

Statistics Theory · Mathematics 2026-02-25 Chang Jun Im , Jeong Min Jeon

We investigate the statistics of trees grown from some initial tree by attaching links to preexisting vertices, with attachment probabilities depending only on the valence of these vertices. We consider the asymptotic mass distribution that…

Statistical Mechanics · Physics 2007-05-23 François David , Philippe Di Francesco , Emmanuel Guitter , Thordur Jonsson

Phylogenetic trees constitute an interesting class of objects for stochastic processes due to the non-standard nature of the space they inhabit. In particular, many statistical applications require the construction of Markov processes on…

Probability · Mathematics 2024-10-24 Rodrigo B. Alves , Yuri F. Saporito , Luiz M. Carvalho

Phylogenetic tree shapes capture fundamental signatures of evolution. We consider ``ranked'' tree shapes, which are equipped with a total order on the internal nodes compatible with the tree graph. Recent work has established an elegant…

Populations and Evolution · Quantitative Biology 2026-03-10 Chris Jennings-Shaffer , Ziyue , Chen , Julia A Palacios , Frederick A Matsen

In this paper we propose a new approach to the central limit theorem (CLT), based on functions of bounded F\'echet variation for the continuously differentiable linear statistics of random matrix ensembles which relies on: a weaker form of…

Probability · Mathematics 2022-01-12 Mario Diaz , James A. Mingo

Phylogenetics is now fundamental in life sciences, providing insights into the earliest branches of life and the origins and spread of epidemics. However, finding suitable phylogenies from the vast space of possible trees remains…

Populations and Evolution · Quantitative Biology 2024-01-24 Matthew J Penn , Neil Scheidwasser , Joseph Penn , Christl A Donnelly , David A Duchêne , Samir Bhatt

Differentiation in mathematical analysis is commonly built by using {\epsilon}-{\delta}-language. This approach also works similarly for defining continuity, Gateaux (directional) derivative and Frechet derivative in normed vector spaces,…

Functional Analysis · Mathematics 2026-05-01 Jinlu Li

Cancers follow a clonal Darwinian evolution, with fitter subclones replacing more quiescent cells, ultimately giving rise to macroscopic disease. High-throughput genomics provides the opportunity to investigate these processes and determine…

Quantitative Methods · Quantitative Biology 2014-10-07 Sakellarios Zairis , Hossein Khiabanian , Andrew J. Blumberg , Raul Rabadan
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