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We have studied the pearling instability induced on hollow tubular lipid vesicles by hydrophilic polymers with hydrophobic side groups along the backbone. The results show that the polymer concentration is coupled to local membrane…

We investigate the instability of a tubular fluid membranes made of a water soluble surfactant. The tubules are obtained at high salinities. The instability is due to the introduction within the vesicle multilayer of an alkane. We measure…

Soft Condensed Matter · Physics 2015-06-25 Sahraoui Chaieb , Sergio Rica

We present a novel buckling instability relevant to membrane budding in eukaryotic cells. In this mechanism, curved filaments bind to a lipid bilayer without changing its intrinsic curvature. As more and more filaments adsorb, newly added…

Biological Physics · Physics 2009-07-16 Martin Lenz , Daniel J. G. Crow , Jean-François Joanny

Plasma membrane tubes are ubiquitous in cellular membranes and in the membranes of intracellular organelles. They play crucial roles in trafficking, ion transport, and cellular motility. The formation of plasma membrane tubes can be due to…

Soft Condensed Matter · Physics 2022-06-09 Arijit Mahapatra , Padmini Rangamani

A phase-field model for dealing with dynamic instabilities in membranes is presented. We use it to study curvature-driven pearling instability in vesicles induced by the anchorage of amphiphilic polymers on the membrane. Within this model,…

Quantitative Methods · Quantitative Biology 2011-11-10 F. Campelo , A. Hernandez-Machado

Cell shape changes are largely controlled by the actin cytoskeleton, a dynamic filament network beneath the plasma membrane. Several cell types can form extended free-standing protrusions not supported by an extracellular substrate or…

Soft Condensed Matter · Physics 2025-10-21 Kristiana Mihali , Dennis Wörthmüller , Pierre Sens

Gradual disruption of the actin cytoskeleton induces a series of structural shape changes in cells leading to a transformation of cylindrical cell extensions into a periodic chain of "pearls". Quantitative measurements of the pearling…

Biological Physics · Physics 2010-08-06 Roy Bar-Ziv , Tsvi Tlusty , Elisha Moses , Samuel A. Safran , Alexander Bershadsky

At the end of the 19th century, Rayleigh and Plateau explained the physical principle behind the fragmentation of a liquid jet into regular droplets commonly observed in everyday life from a faucet. The classical Rayleigh-Plateau…

Quantitative Methods · Quantitative Biology 2025-06-26 C. Léon , N. Brassard-Jollive , D. Gonzalez-Rodriguez , D. Riveline

There are a great many proteins that localize to and collectively generate curvature in biological fluid membranes. We study changes in the topology of fluid membranes due to the presence of highly anisotropic, curvature-inducing proteins.…

Soft Condensed Matter · Physics 2015-05-19 Kiyotaka Akabori , C. D. Santangelo

Understanding the mechanical instabilities of two-dimensional membranes has strong connection to the subjects of structure instabilities, morphology control and materials failures. In this work, we investigate the plastic mechanism…

Soft Condensed Matter · Physics 2024-04-30 Honghui Sun , Zhenwei Yao

A common mechanism for intracellular transport is the use of controlled deformations of the membrane to create spherical or tubular buds. While the basic physical properties of homogeneous membranes are relatively well-known, the effects of…

Biological Physics · Physics 2009-11-10 Jean-Marc Allain , Cornelis Storm , Aurelien Roux , Martine Ben Amar , Jean-Francois Joanny

Motivated by the mechanics of dynamin-mediated membrane tube fission we analyse the stability of fluid membrane tubes subjected to shear flow in azimuthal direction. We find a novel helical instability driven by the membrane shear flow…

Biological Physics · Physics 2020-07-08 Sami C. Al-Izzi , Pierre Sens , Matthew S. Turner

The interplay of membrane proteins is vital for many biological processes, such as cellular transport, cell division, and signal transduction between nerve cells. Theoretical considerations have led to the idea that the membrane itself…

Soft Condensed Matter · Physics 2016-11-28 Casper van der Wel , Afshin Vahid , Anđela Šarić , Timon Idema , Doris Heinrich , Daniela J. Kraft

Membrane proteins are crucial in regulating biomembrane shapes and controlling the dynamic changes in membrane morphology during essential cellular processes. These proteins can localize to regions with their preferred curvatures (curvature…

Soft Condensed Matter · Physics 2025-05-26 Hiroshi Noguchi

Endocytosis is an essential process by which cells internalize a piece of plasma membrane and material from the outside. In cells with turgor, pressure opposes membrane defor- mations, and increases the amount of force that has to be…

Biological Physics · Physics 2016-02-17 Serge Dmitrieff , François Nédélec

The assembly of curved protein rods on fluid membranes is studied using implicit-solvent meshless membrane simulations. As the rod curvature increases, the rods on a membrane tube assemble along the azimuthal direction first and…

Soft Condensed Matter · Physics 2016-05-18 Hiroshi Noguchi

Induced by proteins within the cell membrane or by differential growth, heating, or swelling, spontaneous curvatures can drastically affect the morphology of thin bodies and induce mechanical instabilities. Yet, the interaction of…

Soft Condensed Matter · Physics 2018-01-31 Matteo Pezzulla , Norbert Stoop , Mark P. Steranka , Abdikhalaq J. Bade , Douglas P. Holmes

Living cells employ excitable reaction-diffusion waves for internal cellular functions, in which curvature-inducing proteins are often involved. However, the role of their mechanochemical coupling is not well understood. Here, we report the…

Soft Condensed Matter · Physics 2022-08-09 Naoki Tamemoto , Hiroshi Noguchi

We propose a mechanism for the stabilization/destabilization of cell membranes by multivalent ions with an emphasis on its implications for the division and fusion of cells. We find that multivalent cations preferentially adsorbed onto a…

Soft Condensed Matter · Physics 2007-05-23 Bae-Yeun Ha

The stability of copolymer tethers is investigated theoretically. Self-assembly of diblockor triblock copolymers can lead to tubular polymersomes which are known experimentallyto undergo shape instability under thermal, chemical and tension…

Soft Condensed Matter · Physics 2022-01-12 J. Lyu , K. Xie , R. Chachanidze , A. Kahli , G. Boedec , M. Leonetti
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