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False discovery rate (FDR) has been widely used as an error measure in large scale multiple testing problems, but most research in the area has been focused on procedures for controlling the FDR based on independent test statistics or the…

Methodology · Statistics 2009-09-29 Weihua Tang , Cun-Hui Zhang

Recent years have seen advances in generalization bounds for noisy stochastic algorithms, especially stochastic gradient Langevin dynamics (SGLD) based on stability (Mou et al., 2018; Li et al., 2020) and information theoretic approaches…

Machine Learning · Computer Science 2022-11-02 Arindam Banerjee , Tiancong Chen , Xinyan Li , Yingxue Zhou

We study the theoretical limits of the $\ell_0$ (quasi) norm based optimization algorithms when employed for solving classical compressed sensing or sparse regression problems. Considering standard contexts with deterministic signals and…

Machine Learning · Statistics 2024-10-11 Mihailo Stojnic

Multiple testing literature contains ample research on controlling false discoveries for hypotheses classified according to one criterion, which we refer to as one-way classified hypotheses. Although simultaneous classification of…

Methodology · Statistics 2019-03-12 Shinjini Nandi , Sanat K. Sarkar

We propose the double robust Lagrange multiplier (DRLM) statistic for testing hypotheses specified on the pseudo-true value of the structural parameters in the generalized method of moments. The pseudo-true value is defined as the minimizer…

Econometrics · Economics 2021-05-19 Frank Kleibergen , Zhaoguo Zhan

Confidence intervals are a fundamental tool for quantifying the uncertainty of parameters of interest. With the increase of data privacy awareness, developing a private version of confidence intervals has gained growing attention from both…

Methodology · Statistics 2024-04-12 Shurong Lin , Mark Bun , Marco Gaboardi , Eric D. Kolaczyk , Adam Smith

Duplicate question detection (DQD) is important to increase efficiency of community and automatic question answering systems. Unfortunately, gathering supervised data in a domain is time-consuming and expensive, and our ability to leverage…

Computation and Language · Computer Science 2020-11-24 Yadollah Yaghoobzadeh , Alexandre Rochette , Timothy J. Hazen

Studying the function of proteins is important for understanding the molecular mechanisms of life. The number of publicly available protein structures has increasingly become extremely large. Still, the determination of the function of a…

Machine Learning · Computer Science 2018-03-02 Wajdi Dhifli , Abdoulaye Baniré Diallo

Multiple tests are designed to test a whole collection of null hypotheses simultaneously. Their quality is often judged by the false discovery rate (FDR), i.e. the expectation of the quotient of the number of false rejections divided by the…

Statistics Theory · Mathematics 2015-11-24 Julia Benditkis , Philipp Heesen , Arnold Janssen

Reinforcement Learning with Verifiable Rewards (RLVR) strengthens LLM reasoning, but training often oscillates between {entropy collapse} and {entropy explosion}. We trace both hazards to the mean baseline used in value-free RL (e.g., GRPO…

Machine Learning · Computer Science 2026-03-03 Junkang Wu , Kexin Huang , Jiancan Wu , An Zhang , Xiang Wang , Xiangnan He

Multiple comparisons in hypothesis testing often encounter structural constraints in various applications. For instance, in structural Magnetic Resonance Imaging for Alzheimer's Disease, the focus extends beyond examining atrophic brain…

Methodology · Statistics 2023-11-08 Yang Cao , Xinwei Sun , Yuan Yao

Online multiple hypothesis testing has attracted a lot of attention in many applications, e.g., anomaly status detection and stock market price monitoring. The state-of-the-art generalized $\alpha$-investing (GAI) algorithms can control…

Methodology · Statistics 2025-08-05 Yifan Zhang , Zijian Wei , Haojie Ren , Changliang Zou

Directed evolution plays an indispensable role in protein engineering that revises existing protein sequences to attain new or enhanced functions. Accurately predicting the effects of protein variants necessitates an in-depth understanding…

Quantitative Methods · Quantitative Biology 2023-06-09 Yang Tan , Bingxin Zhou , Yuanhong Jiang , Yu Guang Wang , Liang Hong

Domain generalization aims to learn a generalizable model from a known source domain for various unknown target domains. It has been studied widely by domain randomization that transfers source images to different styles in spatial space…

Computer Vision and Pattern Recognition · Computer Science 2021-03-04 Jiaxing Huang , Dayan Guan , Aoran Xiao , Shijian Lu

All famous machine learning algorithms that comprise both supervised and semi-supervised learning work well only under a common assumption: the training and test data follow the same distribution. When the distribution changes, most…

Machine Learning · Computer Science 2022-07-15 Ievgen Redko , Emilie Morvant , Amaury Habrard , Marc Sebban , Younès Bennani

As the amount and complexity of genetic information increases it is necessary that we explore some efficient ways of handling these data. This study takes the "divide and conquer" approach for analyzing high dimensional genomic data. Our…

Applications · Statistics 2013-08-15 Deniz Akdemir

In applied multivariate statistics, estimating the number of latent dimensions or the number of clusters, $k$, is a fundamental and recurring problem. We study a sequence of statistics called "cross-validated eigenvalues." Under a large…

Methodology · Statistics 2025-12-24 Fan Chen , Sebastien Roch , Karl Rohe , Shuqi Yu

Statistical decision algorithms are increasingly deployed in domains where ground-truth labels are hard to obtain, such as hiring, university admissions, and content moderation. In these settings, models are typically trained on historical…

Machine Learning · Computer Science 2026-05-21 Calvin Isley , Johann D. Gaebler , Sharad Goel

We propose a general and flexible procedure for testing multiple hypotheses about sequential (or streaming) data that simultaneously controls both the false discovery rate (FDR) and false nondiscovery rate (FNR) under minimal assumptions…

Methodology · Statistics 2019-01-14 Jay Bartroff , Jinlin Song

Though deep neural networks have achieved impressive success on various vision tasks, obvious performance degradation still exists when models are tested in out-of-distribution scenarios. In addressing this limitation, we ponder that the…

Computer Vision and Pattern Recognition · Computer Science 2023-01-18 Xiaotong Li , Zixuan Hu , Jun Liu , Yixiao Ge , Yongxing Dai , Ling-Yu Duan
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