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Traditionally, phylogeny and sequence alignment are estimated separately: first estimate a multiple sequence alignment and then infer a phylogeny based on the sequence alignment estimated in the previous step. However, uncertainty in the…

Applications · Statistics 2014-11-25 Heejung Shim , Bret Larget

In sequence-based predictions, conventionally an input sequence is represented by a multiple sequence alignment (MSA) or a representation derived from MSA, such as a position-specific scoring matrix. Recently, inspired by the development in…

Quantitative Methods · Quantitative Biology 2021-10-18 Nabil Ibtehaz , Daisuke Kihara

This study is to review the approaches used for measuring sentences similarity. Measuring similarity between natural language sentences is a crucial task for many Natural Language Processing applications such as text classification,…

Computation and Language · Computer Science 2019-10-10 Mamdouh Farouk

Mapping between sequence and structure is currently an open problem in structural biology. Despite many experimental and computational efforts it is not clear yet how the structure is encoded in the sequence. Answering this question may…

Biomolecules · Quantitative Biology 2013-10-08 Iddo Friedberg

In genomics, pattern matching against a sequence of nucleotides plays a pivotal role for DNA sequence alignment and comparing genomes. This helps tackling some diseases, such as cancer in humans. The complexity of searching biological…

Quantitative Methods · Quantitative Biology 2017-10-04 Fereshte Mozafari , Hossein Babashah , Somayyeh Koohi , Zahra Kavehvash

When can we say that two neural systems perform a task in the same way? What nuances do we miss when we fail to causally probe the representations of the systems, and how do we establish bidirectional causal relationships? In this work, we…

Machine Learning · Computer Science 2025-11-04 Satchel Grant

Exact structured inference with neural network scoring functions is computationally challenging but several methods have been proposed for approximating inference. One approach is to perform gradient descent with respect to the output…

Computation and Language · Computer Science 2019-07-09 Lifu Tu , Kevin Gimpel

In this paper ensemble learning based feature selection and classifier ensemble model is proposed to improve classification accuracy. The hypothesis is that good feature sets contain features that are highly correlated with the class from…

Machine Learning · Computer Science 2020-10-28 Tipawan Silwattananusarn , Wanida Kanarkard , Kulthida Tuamsuk

New proposed models are often compared to state-of-the-art using statistical significance testing. Literature is scarce for classifier comparison using metrics other than accuracy. We present a survey of statistical methods that can be used…

Machine Learning · Computer Science 2016-11-17 Lovedeep Gondara

In this research endeavor, some Sequence Alignment Algorithms are detailed that are useful for finding or comparing 1 dimensional (1-D), 2 dimensional (2-D), 3 dimensional (3-D) sequences in or against a parent or mother database which is 1…

Data Structures and Algorithms · Computer Science 2010-11-03 Ramesh C. Bagadi

Measuring inter-dataset similarity is an important task in machine learning and data mining with various use cases and applications. Existing methods for measuring inter-dataset similarity are computationally expensive, limited, or…

Machine Learning · Computer Science 2025-05-06 Muhammad Rajabinasab , Anton D. Lautrup , Arthur Zimek

Testing of deep learning models is challenging due to the excessive number and complexity of computations involved. As a result, test data selection is performed manually and in an ad hoc way. This raises the question of how we can…

Machine Learning · Computer Science 2019-05-01 Wei Ma , Mike Papadakis , Anestis Tsakmalis , Maxime Cordy , Yves Le Traon

Summary: Longer sequencing reads, with at least 200 bases per template are now common. While traditional aligners have adopted new strategies to improve the mapping of longer reads, aligners specific to bisulfite-sequencing were optimized…

Genomics · Quantitative Biology 2014-05-14 Brent S. Pedersen , Kenneth Eyring , Subhajyoti De , Ivana V. Yang , David A. Schwartz

Deep learning for object classification relies heavily on convolutional models. While effective, CNNs are rarely interpretable after the fact. An attention mechanism can be used to highlight the area of the image that the model focuses on…

Computer Vision and Pattern Recognition · Computer Science 2019-03-18 Paresh Malalur , Tommi Jaakkola

Music similarity search is useful for a variety of creative tasks such as replacing one music recording with another recording with a similar "feel", a common task in video editing. For this task, it is typically necessary to define a…

Audio and Speech Processing · Electrical Eng. & Systems 2020-08-14 Jongpil Lee , Nicholas J. Bryan , Justin Salamon , Zeyu Jin , Juhan Nam

This paper presents a novel DNA sequences alignment method based on inverted index. Now most large scale information retrieval system are all use inverted index as the basic data structure. But its application in DNA sequence alignment is…

Genomics · Quantitative Biology 2013-07-02 Wang Liang , Zhao KaiYong

Data mining is the task of discovering interesting patterns from large amounts of data. There are many data mining tasks, such as classification, clustering, association rule mining, and sequential pattern mining. Sequential pattern mining…

Databases · Computer Science 2010-02-08 Mahdi Esmaeili , Fazekas Gabor

A new set of DNA base-nucleic acid codes and their hypercomplex number representation have been introduced for taking the probability of each nucleotide into full account. A new scoring system has been proposed to suit the hypercomplex…

Other Quantitative Biology · Quantitative Biology 2014-03-12 Jian-Jun Shu , Li Shan Ouw

Protein sequence classification involves feature selection for accurate classification. Popular protein sequence classification techniques involve extraction of specific features from the sequences. Researchers apply some well-known…

Computational Engineering, Finance, and Science · Computer Science 2012-11-21 Suprativ Saha , Rituparna Chaki

Low-dimensional embeddings for data from disparate sources play critical roles in multi-modal machine learning, multimedia information retrieval, and bioinformatics. In this paper, we propose a supervised dimensionality reduction method…

Machine Learning · Computer Science 2021-01-15 Yanjun Li , Bihan Wen , Hao Cheng , Yoram Bresler