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Although large language models (LLMs) are highly interactive and extendable, current approaches to ensure reliability in deployments remain mostly limited to rejecting outputs with high uncertainty in order to avoid misinformation. This…

Machine Learning · Computer Science 2025-06-10 T. Duy Nguyen-Hien , Desi R. Ivanova , Yee Whye Teh , Wee Sun Lee

With the evolution of large language models (LLMs), their robustness against individual simple biases has been enhanced. However, we observe that the ensemble of multiple simple biases still exerts a significant adverse impact on LLMs.…

Computation and Language · Computer Science 2026-04-21 Zhouhao Sun , Zhiyuan Kan , Xiao Ding , Li Du , Bibo Cai , Yang Zhao , Bing Qin , Ting Liu

Generalized Entity Matching (GEM), which aims at judging whether two records represented in different formats refer to the same real-world entity, is an essential task in data management. The prompt tuning paradigm for pre-trained language…

Computation and Language · Computer Science 2024-05-09 Yikuan Xia , Jiazun Chen , Xinchi Li , Jun Gao

In the AGEMAP genomics study, researchers were interested in detecting genes related to age in a variety of tissue types. After not finding many age-related genes in some of the analyzed tissue types, the study was criticized for having low…

Methodology · Statistics 2015-06-08 Patrick O. Perry , Natesh S. Pillai

In this paper, we explore the potential of Large Language Models (LLMs) with assertions to mitigate imbalances in educational datasets. Traditional models often fall short in such contexts, particularly due to the complexity and nuanced…

Computers and Society · Computer Science 2024-07-03 Jeanne McClure , Machi Shimmei , Noboru Matsuda , Shiyan Jiang

Objective: This study investigates the potential of Large Language Models (LLMs) as an alternative to human expert elicitation for extracting structured causal knowledge and facilitating causal modeling in biometric and healthcare…

Artificial Intelligence · Computer Science 2025-04-15 Olha Shaposhnyk , Daria Zahorska , Svetlana Yanushkevich

The emergence of Large Language Models (LLMs) as chat assistants capable of generating human-like conversations has amplified the need for robust evaluation methods, particularly for open-ended tasks. Conventional metrics such as EM and F1,…

Computation and Language · Computer Science 2025-11-12 Sher Badshah , Hassan Sajjad

Despite the utility of Large Language Models (LLMs) across a wide range of tasks and scenarios, developing a method for reliably evaluating LLMs across varied contexts continues to be challenging. Modern evaluation approaches often use LLMs…

Computation and Language · Computer Science 2024-01-31 Steffi Chern , Ethan Chern , Graham Neubig , Pengfei Liu

This paper studies the high-dimensional mixed linear regression (MLR) where the output variable comes from one of the two linear regression models with an unknown mixing proportion and an unknown covariance structure of the random…

Methodology · Statistics 2020-11-10 Linjun Zhang , Rong Ma , T. Tony Cai , Hongzhe Li

Considerable interest has recently been focused on studying multiple phenotypes simultaneously in both epidemiological and genomic studies, either to capture the multidimensionality of complex disorders or to understand shared etiology of…

Methodology · Statistics 2015-11-26 Denis Agniel , Katherine P. Liao , Tianxi Cai

There is a considerable literature in case-control logistic regression on whether or not non-confounding covariates should be adjusted for. However, only limited and ad hoc theoretical results are available on this important topic. A…

Statistics Theory · Mathematics 2023-05-19 Siliang Zhang , Jinbo Chen , Zhiliang Ying , Hong Zhang

Modern data sets in various domains often include units that were sampled non-randomly from the population and have a latent correlation structure. Here we investigate a common form of this setting, where every unit is associated with a…

Methodology · Statistics 2019-07-25 Omer Weissbrod , Shachar Kaufman , David Golan , Saharon Rosset

The era of Large Language Models (LLMs) raises new demands for automatic evaluation metrics, which should be adaptable to various application scenarios while maintaining low cost and effectiveness. Traditional metrics for automatic text…

Computation and Language · Computer Science 2024-10-29 Shuqian Sheng , Yi Xu , Tianhang Zhang , Zanwei Shen , Luoyi Fu , Jiaxin Ding , Lei Zhou , Xiaoying Gan , Xinbing Wang , Chenghu Zhou

We present a new approach for benchmarking Large Language Model (LLM) capabilities on research-level mathematics. Existing benchmarks largely rely on static, hand-curated sets of contest or textbook-style problems as proxies for…

Artificial Intelligence · Computer Science 2026-03-02 Antoine Peyronnet , Fabian Gloeckle , Amaury Hayat

The Connectivity Map (CMap) is a large publicly available database of cellular transcriptomic responses to chemical and genetic perturbations built using a standardized acquisition protocol known as the L1000 technique. Databases such as…

Quantitative Methods · Quantitative Biology 2024-05-01 Steven Shave , Richard Kasprowicz , Abdullah M. Athar , Denise Vlachou , Neil O. Carragher , Cuong Q. Nguyen

Reinforcement learning (RL) methods have been shown to be capable of learning intelligent behavior in rich domains. However, this has largely been done in simulated domains without adequate focus on the process of building the simulator. In…

Machine Learning · Computer Science 2019-10-24 Aditya Modi , Nan Jiang , Ambuj Tewari , Satinder Singh

Although language model scores are often treated as probabilities, their reliability as probability estimators has mainly been studied through calibration, overlooking other aspects. In particular, it is unclear whether language models…

Computation and Language · Computer Science 2024-10-01 Eitan Wagner , Yuli Slavutsky , Omri Abend

Large-scale biobanks are being collected around the world in efforts to better understand human health and risk factors for disease. They often survey hundreds of thousands of individuals, combining questionnaires with clinical, genetic,…

Quantitative Methods · Quantitative Biology 2019-03-19 Qifan Yang , Gennady V. Roshchupkin , Wiro J. Niessen , Sarah E. Medland , Alyssa H. Zhu , Paul M. Thompson , Neda Jahanshad

Large Reasoning Models (LRMs) have the ability to self-correct even when they make mistakes in their reasoning paths. However, our study reveals that when the reasoning process starts with a short but poor beginning, it becomes difficult…

Computation and Language · Computer Science 2025-05-13 Tongxu Luo , Wenyu Du , Jiaxi Bi , Stephen Chung , Zhengyang Tang , Hao Yang , Min Zhang , Benyou Wang

Linear mixed-effects model (LMM) is a cornerstone of longitudinal data analysis, but is limited to adeptly make heterogeneous analyses predictable under both group-specific fixed effects and subject-specific random effects. To address this…

Methodology · Statistics 2026-03-10 Xinkai Yue , Xiaodong Yan , Haohui Han , Liya Fu