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Information processing and decision making is based upon logic operations, which in cellular networks has been well characterized at the level of transcription. In recent years however, both experimentalists and theorists have begun to…

Molecular Networks · Quantitative Biology 2012-09-11 Wiet de Ronde , Pieter Rein ten Wolde , Andrew Mugler

Recent work in the machine learning literature has demonstrated that deep learning can train neural networks made of discrete logic gate functions to perform simple image classification tasks at very high speeds on CPU, GPU and FPGA…

Computer Vision and Pattern Recognition · Computer Science 2026-04-22 Sebastian Fieldhouse , Kea-Tiong Tang

We propose a water-immersed nucleobase-functionalized suspended graphene nanoribbon as an intrinsically selective device for nucleotide detection. The proposed sensing method combines Watson-Crick selective base pairing with graphene's…

Mesoscale and Nanoscale Physics · Physics 2016-02-17 Eugene Paulechka , Tsjerk A. Wassenaar , Kenneth Kroenlein , Andrei Kazakov , Alex Smolyanitsky

We have micromachined a silicon-chip device that transports DNA with a Brownian ratchet that rectifies the Brownian motion of microscopic particles. Transport properties for a DNA 50mer agree with theoretical predictions, and the DNA…

Modern electronics are developing electronic-optical integrated circuits, while their electronic backbone, e.g. field-effect transistors (FETs), remains the same. However, further FET down scaling is facing physical and technical…

Optics · Physics 2020-06-02 Jason K. Marmon , Satish C. Rai , Kai Wang , Weilie Zhou , Yong Zhang

An effective interaction between trapped ions in thermal motion can be generated by illuminating them simultaneously with a single laser resonant with the ionic carrier frequency. The ac Stark-shift induces simultaneous `virtual' two-phonon…

Quantum Physics · Physics 2009-11-07 Daniel Jonathan , Martin B. Plenio

Resonance fluorescence from a single two-level system is a cornerstone of quantum optics. In the strong driving regime, its emission spectrum exhibits the iconic Mollow triplet, with each spectral component corresponding to a transition…

Quantum Physics · Physics 2025-10-01 Yuan Zhan , Zixuan Wang , Richard P. Mirin , Kevin L. Silverman , Shuo Sun

We demonstrate a new, versatile class of nanoscale chemical sensors based on single-stranded DNA (ss-DNA) as the chemical sensors recognition site and single-walled carbon nanotube field effect transistors (swCN-FET) as the electronic…

Materials Science · Physics 2007-05-23 Cristian Staii , Michelle Chen , Alan Gelperin , Alan T. Johnson

In this work we numerically calculate the electric current through three kinds of DNA sequences (telomeric, \lambda-DNA, and p53-DNA) described by different heuristic models. A bias voltage is applied between two zig-zag edged graphene…

Mesoscale and Nanoscale Physics · Physics 2012-10-02 Carlos J. Páez , Peter A. Schulz , Neil Wilson , Rudolf A. Römer

Because of the limitations of classical silicon based computational technology, several alternatives to traditional method in form of unconventional computing have been proposed. In this paper we will focus on DNA computing which is showing…

Biomolecules · Quantitative Biology 2017-03-31 Mandrita Mondal , Kumar S. Ray

Charge migration along DNA molecules has attracted scientific interest for over half a century. Reports on possible high rates of charge transfer between donor and acceptor through the DNA, obtained in the last decade from solution…

Materials Science · Physics 2009-11-10 Danny Porath , Gianaurelio Cuniberti , Rosa Di Felice

Scalable production of all-electronic DNA biosensors with high sensitivity and selectivity is a critical enabling step for research and applications associated with detection of DNA hybridization. We have developed a scalable and very…

Applied Physics · Physics 2017-08-31 Jinglei Ping , Ramya Vishnubhotla , Amey Vrudhula , A. T. Charlie Johnson

DNA and protein microarrays are a high-throughput technology that allow the simultaneous quantification of tens of thousands of different biomolecular species. The mediocre sensitivity and dynamic range of traditional fluorescence…

Biomolecules · Quantitative Biology 2018-01-24 Derin Sevenler , George Daaboul , Fulya Ekiz-Kanik , M. Selim Unlu

The retina is one of the best known quantum detectors with rods able to respond to a single photon. However, estimates on the number of photons eliciting conscious perception, based on signal detection theory, are systematically above these…

A fluorescence system is developed by using several light emitting diodes (LEDs) with different wavelengths as excitation light sources. The fluorescence detection head consists of multi LED light sources and a multimode fiber for…

Optics · Physics 2013-11-19 Yongjiang Dong , Xuan Liu , Liang Mei , Chao Feng , Chunsheng Yan , Sailing He

The success of graphene for nanopore DNA sequencing has shown that it is possible to explore other potential single-atom and few-atom thick layers of elemental 2D materials beyond graphene (e.g., phosphorene and silicene). Using density…

Mesoscale and Nanoscale Physics · Physics 2021-12-15 Matthew B. Henry , Mukesh Tumbapo , Benjamin O. Tayo

Neuromorphic architectures are ideally suited for the implementation of smart sensors able to react, learn, and respond to a changing environment. Our work uses the insect brain as a model to understand how heterogeneous architectures,…

Neural and Evolutionary Computing · Computer Science 2021-04-12 Angel Yanguas-Gil

Future experiments of nuclear and particle physics are moving towards the high luminosity regime, in order to access suppressed processes like rare B decays or exotic charmonium resonances. In this scenario, high rate capability is a key…

Instrumentation and Detectors · Physics 2015-02-18 M. Cardinali , O. Corell , M. I. Ferretti Bondy , M. Hoek , W. Lauth , C. Rosner , C. Sfienti , M. Thiel

A new powerful longitudinal diagnostics is being developed for the two CERN's antiproton machines, the Antiproton Decelerator (AD) and the Extra Low ENergy ANtiproton (ELENA) ring. The longitudinal diagnostics receives data from the…

The passage of DNA through a nanopore can be effectively decomposed into two distinct phases, docking and actual translocation. In experiments each phase is characterized by a distinct current signature which allows the discrimination of…