Related papers: Development of a DNA sensor using molecular logic …
The determination of a patient's DNA sequence can, in principle, reveal an increased risk to fall ill with particular diseases [1,2] and help to design "personalized medicine" [3]. Moreover, statistical studies and comparison of genomes [4]…
Charge transport through a short DNA oligomer (Dickerson dodecamer) in presence of structural fluctuations is investigated using a hybrid computational methodology based on a combination of quantum mechanical electronic structure…
Atmospheric effects, such as turbulence and background thermal noise, inhibit the propagation of coherent light used in ON-OFF keying free-space optical communication. Here we present and experimentally validate a convolutional neural…
The genetic information that dictates the structure and function of all life forms is encoded in the DNA. In 1953, Watson and Crick first presented the double helical structure of a DNA molecule. Their findings unearthed the desire to…
Sensitive biomarker detection in physiological fluids is often limited by Debye screening, which suppresses electrostatic signals at sensor surfaces. Here we report a sensing approach based on flexoelectric resonance in silicon nanowire…
Optical qubits uniquely combine information transfer in optical fibers with a good processing capability and are therefore attractive tools for quantum technologies. A large challenge, however, is to overcome the low efficiency of two-qubit…
Artificial intelligence has emerged as promising tool to decode a phase image transmitted through a multimode fiber (MMF) by applying deep learning techniques. By transmitting tens of thousands of images through the MMF, deep neural…
DNA strand displacement (SD) reactions are central to the operation of many synthetic nucleic acid systems, including molecular circuits, sensors, and machines. Over the years, a broad set of design frameworks has emerged to accommodate…
We describe two different modes for electronically detecting an adsorbed molecule using a nanoscale transistor. The attachment of an ionic molecular target shifts the threshold voltage through modulation of the depletion layer…
Genetic analysis methods are foundational to advancing personalized and preventative medicine, accelerating disease diagnostics, and monitoring the health of organisms and ecosystems. Current nucleic acid technologies such as polymerase…
We implemented a nanoelectronic interface between graphene field effect transistors (FETs) and soluble proteins. This enables production of bioelectronic devices that combine functionalities of the biomolecular and inorganic components. The…
We investigate the computing power of a restricted class of DNA strand displacement structures: those that are made of double strands with nicks (interruptions) in the top strand. To preserve this structural invariant, we impose…
In this paper initial experiments towards constructing simple quantum gates in a solid state material are presented. Instead of using specially tailored materials, the aim is to select a subset of randomly distributed ions in the material,…
Recent advances in next-generation sequencing technologies have facilitated the use of deoxyribonucleic acid (DNA) as a novel covert channels in steganography. There are various methods that exist in other domains to detect hidden messages…
Plasmonic nanopores combine nanofluidic confinement with electromagnetic field enhancement, enabling optical interrogation of single molecules in sub-wavelength volumes. Yet, direct optical readout within these metallic geometries has…
Low-latency, energy-efficient deep neural networks (DNNs) inference are critical for edge applications, where traditional cloud-based deployment suffers from high latency and security risks. Field-Programmable Gate Arrays (FPGAs) offer a…
The decoherence effect caused by the coupling between the system and the environment undoubtedly leads to the errors in efficient implementations of two (or three) qubit logical gates in quantum information processing. Fortunately,…
The photophysical properties of deoxyribonucleic acid (DNA) are fundamental to life sciences and biophotonics. While previous studies have generally been restricted to fluorescence, attributing it to pi-pi* transitions and charge transfer…
By using the memristor's memory to both store a bit and perform an operation with a second input bit, simple Boolean logic gates have been built with a single memristor. The operation makes use of the interaction of current spikes…
We employ noise spectroscopy and transconductance measurements to establish the optimal regimes of operation for our fabricated silicon nanowire field-effect transistors (Si NW FETs) sensors. A strong coupling between the liquid gate and…