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In 2011 the DNA seesaw gate motif was introduced. It is a powerful feed-forward DNA nanodevice that can perform digital logic computations. The landmark of that work managed to evaluate moderately large Boolean circuits by cascading…

Emerging Technologies · Computer Science 2019-02-05 Abeer Eshra , Shalin Shah , John Reif

Recent advances in Fluorescence Resonance Energy Transfer (FRET) provides a way to measure and understand different biological systems and molecular interactions in nanometer order. In this report the introduction and principle of the FRET…

General Physics · Physics 2009-08-14 Syed Arshad Hussain

Fluorescence spectroscopy and modeling provide powerful means to characterize biomacromolecular structures, dynamics, and interactions. F\"orster resonance energy transfer serves as a key technique for this due to its nanometer-scale…

Biological Physics · Physics 2026-02-26 Thomas-Otavio Peulen , Daria Maksutova , Thorben Cordes

Structural and functional information encoded in DNA combined with unique properties of nanomaterials could be of use for the construction of novel biocomputational circuits and intelligent biomedical nanodevices. However, at present their…

Materials Science · Physics 2013-07-16 Jun Zhang , Cuong Cao , Xinlong Xu , Chihao Liow , Shuzhou Li , Ping-Heng Tan , Qihua Xiong

Nanophotonics achieves accurate control over the luminescence properties of a single quantum emitter by tailoring the light-matter interaction at the nanoscale and modifying the local density of optical states (LDOS). This paradigm could…

We report high time-resolution measurements of photon statistics from pairs of dye molecules coupled by fluorescence resonance energy transfer (FRET). In addition to quantum-optical photon antibunching, we observe photon bunching on a…

Condensed Matter · Physics 2009-11-07 Andrew J. Berglund , Andrew C. Doherty , Hideo Mabuchi

The paper is concerned with Forster Resonance Energy Transfer (FRET) considered as a mechanism for communication between nanodevices. Two solved issues are reported in the paper, namely: signal generation and signal storage in FRET-based…

Medical Physics · Physics 2019-12-05 Jakub Kmiecik , Krzysztof Wojcik , Pawel Kulakowski , Andrzej Jajszczyk

A purely electrical sensing scheme is presented that determines the concentration of macromolecules in solution by measuring the capacitance between planar microelectrodes. Concentrations of DNA in the ng/mL range have been used in samples…

Biological Physics · Physics 2009-01-20 Anja Henning , Joerg Henkel , Frank F Bier , Ralph Hoelzel

Synthetic molecular motors are an appealing means to control motion at the nanoscale, but understanding their behaviour as single-molecule actuators and integrating them into larger, functional systems remain technical challenges.…

Optical logic has the potential to replace electronics with photonic circuits in applications for which optic-to-electronic conversion is impractical and for integrated all-optical circuits. Nonlinear optics in whispering gallery mode…

Optically-active spin qubits have emerged as powerful quantum sensors capable of nanoscale magnetometry, yet conventional coherent sensing approaches are ultimately limited by the coherence time of the sensor, typically precluding detection…

Quantum Physics · Physics 2025-10-10 Nicole Voce , Paul Stevenson

We review enzymatic systems which involve biocatalytic reactions utilized for information processing (biocomputing). Extensive ongoing research in biocomputing, mimicking Boolean logic gates has been motivated by potential applications in…

Biological Physics · Physics 2010-10-12 Evgeny Katz , Vladimir Privman

A method is presented for the sensing of water hardness by determining the concentration of calcium and magnesium in water, based on Fluorescence resonance energy transfer (FRET) process. The principle of the proposed sensor is based on the…

Materials Science · Physics 2014-09-16 Dibyendu Dey , D. Bhattacharjee , S. Chakraborty , Syed Arshad Hussain

Based on the understanding that chemical bonds can act as tunnel junctions in the Coulomb blockade regime, and on the technical ability to coat a DNA strand with metal, we suggest that DNA can be used to built logical devices. We discuss…

Biological Physics · Physics 2007-05-23 Eshel Ben-Jacob , Ziv Hermon , Shay Caspi

All-optical switches are introduced which are based on deoxyribonucleic acid (DNA) in the form of electrospun fibers, where DNA is semi-intercalated with a push-pull, luminescent nonlinear pyrazoline derivative. Optical birefringence is…

Applied Physics · Physics 2018-12-18 Adam Szukalski , Maria Moffa , Andrea Camposeo , Dario Pisignano , Jaroslaw Mysliwiec

We demonstrate simultaneous measurements of DNA translocation into glass nanopores using ionic current detection and fluorescent imaging. We verify the correspondence between the passage of a single DNA molecule through the nanopore and the…

Graphene is a true two dimensional material with exceptional electronic properties and enormous potential for practical applications. Graphene's promise as a chemical sensor material has been noted but there has been relatively little work…

Mesoscale and Nanoscale Physics · Physics 2015-05-19 Ye Lu , Brett R. Goldsmith , Nicholas J. Kybert , A. T. Charlie Johnson

Applications of Fluorescence Resonance Energy Transfer (FRET) in biology have expanded tremendously in the last 25 years. This technique has become a staple technique in many biological and biophysical fields. FRET based chemical sensors…

Biological Physics · Physics 2020-05-05 Ripa Paul , Sudip Suklabaidya , Syed Arshad Hussain

Recently, research has increasingly focused on developing efficient neural network architectures. In this work, we explore logic gate networks for machine learning tasks by learning combinations of logic gates. These networks comprise logic…

Machine Learning · Computer Science 2022-10-18 Felix Petersen , Christian Borgelt , Hilde Kuehne , Oliver Deussen

We present a rapid-scanning approach to fluorescence-detected two-dimensional electronic spectroscopy that combines acousto-optic phase-modulation with digital lock-in detection. The approach shifts the signal detection window to suppress…