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Conventional mutual information (MI) based feature selection (FS) methods are unable to handle heterogeneous feature subset selection properly because of data format differences or estimation methods of MI between feature subset and class…

Machine Learning · Statistics 2015-03-31 Min Wei , Tommy W. S. Chow , Rosa H. M. Chan

Proteins are arguably the most important class of biomarkers for health diagnostic purposes. Label-free solid-state nanopore sensing is a versatile technique for sensing and analysing biomolecules such as proteins at single-molecule level.…

Multispectral image pairs can provide the combined information, making object detection applications more reliable and robust in the open world. To fully exploit the different modalities, we present a simple yet effective cross-modality…

Image and Video Processing · Electrical Eng. & Systems 2022-10-05 Fang Qingyun , Han Dapeng , Wang Zhaokui

The performance of face detectors has been largely improved with the development of convolutional neural network. However, it remains challenging for face detectors to detect tiny, occluded or blurry faces. Besides, most face detectors…

Computer Vision and Pattern Recognition · Computer Science 2019-04-26 Wanxin Tian , Zixuan Wang , Haifeng Shen , Weihong Deng , Yiping Meng , Binghui Chen , Xiubao Zhang , Yuan Zhao , Xiehe Huang

The correct prediction of protein secondary structures is one of the key issues in predicting the correct protein folded shape, which is used for determining gene function. Existing methods make use of amino acids properties as indices to…

Quantitative Methods · Quantitative Biology 2017-05-01 Jian-Jun Shu , Kian-Yan Yong

Accurately modeling the protein fitness landscapes holds great importance for protein engineering. Recently, due to their capacity and representation ability, pre-trained protein language models have achieved state-of-the-art performance in…

Biomolecules · Quantitative Biology 2024-02-06 Ziyi Zhou , Liang Zhang , Yuanxi Yu , Mingchen Li , Liang Hong , Pan Tan

Protein fitness optimization involves finding a protein sequence that maximizes desired quantitative properties in a combinatorially large design space of possible sequences. Recent advances in steering protein generative models (e.g.,…

Biomolecules · Quantitative Biology 2025-10-22 Jason Yang , Wenda Chu , Daniel Khalil , Raul Astudillo , Bruce J. Wittmann , Frances H. Arnold , Yisong Yue

Nucleic acid-based drugs like aptamers have recently demonstrated great therapeutic potential. However, experimental platforms for aptamer screening are costly, and the scarcity of labeled data presents a challenge for supervised methods to…

Biomolecules · Quantitative Biology 2024-11-05 Tinglin Huang , Zhenqiao Song , Rex Ying , Wengong Jin

Causal discovery is a crucial initial step in establishing causality from empirical data and background knowledge. Numerous algorithms have been developed for this purpose. Among them, the score-matching method has demonstrated superior…

Machine Learning · Statistics 2026-04-14 Hao Chen , Kai Yi

In experimental nuclear and particle physics, the extraction of high-purity samples of rare events critically depends on the efficiency and accuracy of particle identification (PID). In this work, we present a PID method applied to HADES…

Data Analysis, Statistics and Probability · Physics 2025-11-18 Marvin Kohls

Online string matching is a computational problem involving the search for patterns or substrings in a large text dataset, with the pattern and text being processed sequentially, without prior access to the entire text. Its relevance stems…

Data Structures and Algorithms · Computer Science 2023-10-25 Matthew N. Palmer , Simone Faro , Stefano Scafiti

Biometrics based personal identification is regarded as an effective method for automatically recognizing, with a high confidence a person's identity. A multimodal biometric systems consolidate the evidence presented by multiple biometric…

Computer Vision and Pattern Recognition · Computer Science 2009-09-15 M. Nageshkumar , P. K. Mahesh , M. N. S. Swamy

Model fusion is a key strategy for robust recognition in unconstrained scenarios, as different models provide complementary strengths. This is especially important for whole-body human recognition, where biometric cues such as face, gait,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Jie Zhu , Xiao Guo , Yiyang Su , Anil Jain , Xiaoming Liu

Determining the localization of specific protein in human cells is important for understanding cellular functions and biological processes of underlying diseases. Among imaging techniques, high-throughput fluorescence microscopy imaging is…

Computer Vision and Pattern Recognition · Computer Science 2019-02-01 Yijun Tian

Test-Time Adaptation (TTA) aims to enhance the generalization of deep learning models when faced with test data that exhibits distribution shifts from the training data. In this context, only a pre-trained model and unlabeled test data are…

Machine Learning · Computer Science 2025-05-19 Linjing You , Jiabao Lu , Xiayuan Huang , Xiangli Nie

The de novo design of proteins refers to creating proteins with specific structures and functions that do not naturally exist. In recent years, the accumulation of high-quality protein structure and sequence data and technological…

Biomolecules · Quantitative Biology 2025-04-24 Yujie Qin , Ming He , Changyong Yu , Ming Ni , Xian Liu , Xiaochen Bo

Most convolutional neural network (CNN) based methods for skin cancer classification obtain their results using only dermatological images. Although good classification results have been shown, more accurate results can be achieved by…

Computer Vision and Pattern Recognition · Computer Science 2023-12-08 Peng Tang , Xintong Yan , Yang Nan , Xiaobin Hu , Xiaobin Hu , Bjoern H Menzee. Sebastian Krammer , Tobias Lasser

In this work, we propose a novel centrality metric, referred to as star centrality, which incorporates information from the closed neighborhood of a node, rather than solely from the node itself, when calculating its topological importance.…

Quantitative Methods · Quantitative Biology 2018-03-15 Chrysafis Vogiatzis , Mustafa Can Camur

Textual data such as tags, sentence descriptions are combined with visual cues to reduce the semantic gap for image retrieval applications in today's Multimodal Image Retrieval (MIR) systems. However, all tags are treated as equally…

Computer Vision and Pattern Recognition · Computer Science 2017-01-11 Shangwen Li , Sanjay Purushotham , Chen Chen , Yuzhuo Ren , C. -C. Jay Kuo

The exponential growth of DNA sequencing data has outpaced traditional heuristic-based methods, which struggle to scale effectively. Efficient computational approaches are urgently needed to support large-scale similarity search, a…

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