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Inferring the structure and dynamics of network models is critical to understanding the functionality and control of complex systems, such as metabolic and regulatory biological networks. The increasing quality and quantity of experimental…

Dynamical Systems · Mathematics 2016-05-27 Niall M. Mangan , Steven L. Brunton , Joshua L. Proctor , J. Nathan Kutz

This paper considers a joint scattering environment sensing and data recovery problem in an uplink integrated sensing and communication (ISAC) system. To facilitate joint scatterers localization and multi-user (MU) channel estimation, we…

Signal Processing · Electrical Eng. & Systems 2025-02-11 An Liu , Wenkang Xu , Wei Xu , Giuseppe Caire

Due to the recent advances in high-throughput sequencing technologies, it becomes possible to directly analyze microbial communities in the human body and in the environment. Knowledge of how microbes interact with each other and form…

Quantitative Methods · Quantitative Biology 2018-07-24 Chieh Lo , Radu Marculescu

In orthogonal frequency division modulation (OFDM) communication systems, channel state information (CSI) is required at receiver due to the fact that frequency-selective fading channel leads to disgusting inter-symbol interference (ISI)…

Information Theory · Computer Science 2015-04-22 Guan Gui , Li Xu , Lin Shan , Fumiyuki Adachi

This paper proposes a hierarchical Bayesian multitask learning model that is applicable to the general multi-task binary classification learning problem where the model assumes a shared sparsity structure across different tasks. We derive a…

Motivation: Estimation of bacterial community composition from a high-throughput sequenced sample is an important task in metagenomics applications. Since the sample sequence data typically harbors reads of variable lengths and different…

The explosion in known microbial diversity in the last two decades has made it abundantly clear that microbes in the environment do not exist in isolation; they are members of communities. Accordingly, omics approaches such as metagenomics…

Quantitative Methods · Quantitative Biology 2024-07-15 James C. Kosmopoulos , Karthik Anantharaman

Enzymes and proteins are live driven biochemicals, which has a dramatic impact over the environment, in which it is active. So, therefore, it is highly looked-for to build such a robust and highly accurate automatic and computational model…

Biomolecules · Quantitative Biology 2021-01-11 Zaheer Ullah Khan , Dechang Pi , Izhar Ahmed Khan , Asif Nawaz , Jamil Ahmad , Mushtaq Hussain

Analyzing large-scale text corpora is a core challenge in machine learning, crucial for tasks like identifying undesirable model behaviors or biases in training data. Current methods often rely on costly LLM-based techniques (e.g.…

Artificial Intelligence · Computer Science 2025-12-12 Nick Jiang , Xiaoqing Sun , Lisa Dunlap , Lewis Smith , Neel Nanda

Microbiome data require statistical models that can simultaneously decode microbes' reaction to the environment and interactions among microbes. While a multiresponse linear regression model seems like a straight-forward solution, we argue…

Applications · Statistics 2022-07-26 Yunyi Shen , Claudia Solis-Lemus

Microorganisms are found in almost every environment, including the soil, water, air, and inside other organisms, like animals and plants. While some microorganisms cause diseases, most of them help in biological processes such as…

Machine Learning · Computer Science 2023-09-28 Daniel Agyapong , Jeffrey Ryan Propster , Jane Marks , Toby Dylan Hocking

Microorganisms play a critical role in host health. The advancement of high-throughput sequencing technology provides opportunities for a deeper understanding of microbial interactions. However, due to the limitations of 16S ribosomal RNA…

Methodology · Statistics 2021-05-12 Hee Cheol Chung , Irina Gaynanova , Yang Ni

High-throughput sequencing has transformed microbiome research, but it also produces inherently compositional data that challenge standard statistical and machine learning methods. In this work, we propose a multinomial classification…

Applications · Statistics 2025-12-23 R. Alberich , N. A. Cruz , R. Fernández , I. García Mosquera , A. Mir , F. Rosselló

Combining data has become an indispensable tool for managing the current diversity and abundance of data. But, as data complexity and data volume swell, the computational demands of previously proposed models for combining data escalate…

Methodology · Statistics 2024-06-13 Mario Figueira , David Conesa , Antonio López-Quílez , Iosu Paradinas

Species distribution models (SDMs) are widely used to predict species' geographic distributions, serving as critical tools for ecological research and conservation planning. Typically, SDMs relate species occurrences to environmental…

Machine Learning · Computer Science 2025-08-12 Hager Radi Abdelwahed , Mélisande Teng , Robin Zbinden , Laura Pollock , Hugo Larochelle , Devis Tuia , David Rolnick

An important task in microbiome studies is to test the existence of and give characterization to differences in the microbiome composition across groups of samples. Important challenges of this problem include the large within-group…

Methodology · Statistics 2019-05-07 Jialiang Mao , Yuhan Chen , Li Ma

Scientific archives now contain hundreds of petabytes of data across genomics, ecology, climate, and molecular biology that could reveal undiscovered patterns if systematically analyzed at scale. Large-scale, weakly-supervised datasets in…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Samuel Stevens , Jacob Beattie , Tanya Berger-Wolf , Yu Su

Electroencephalography (EEG)-based P300 brain-computer interfaces (BCIs) enable communication without physical movement by detecting stimulus-evoked neural responses. Accurate and efficient decoding remains challenging due to high…

Methodology · Statistics 2026-03-02 Guoxuan Ma , Yuan Zhong , Moyan Li , Yuxiao Nie , Jian Kang

Inferring microbial interaction networks from abundance patterns is an important approach to advance our understanding of microbial communities in general and the human microbiome in particular. Here we suggest discriminating two levels of…

Populations and Evolution · Quantitative Biology 2023-06-06 Isabella-Hilda Mendler , Barbara Drossel , Marc-Thorsten Hütt

Human microbiome studies use sequencing technologies to measure the abundance of bacterial species or Operational Taxonomic Units (OTUs) in samples of biological material. Typically the data are organized in contingency tables with OTU…

Methodology · Statistics 2017-03-27 Boyu Ren , Sergio Bacallado , Stefano Favaro , Susan Holmes , Lorenzo Trippa