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Biological circuits such as neural or gene regulation networks use internal states to map sensory input to an adaptive repertoire of behavior. Characterizing this mapping is a major challenge for systems biology, and though experiments that…

Neurons and Cognition · Quantitative Biology 2022-10-12 Edward D. Lee , Xiaowen Chen , Bryan C. Daniels

EEG foundation models achieve state-of-the-art clinical performance, yet the internal computations driving their predictions remain opaque: a barrier to clinical trust. We apply TopK Sparse Autoencoders (SAEs) across three architecturally…

The interactions between microbial taxa in microbiome data has been under great research interest in the science community. In particular, several methods such as SPIEC-EASI, gCoda, and CD-trace have been proposed to model the conditional…

Methodology · Statistics 2022-07-05 Chuan Tian , Duo Jiang , Yuan Jiang

Stochastic differential equations (SDEs) provide a natural framework for modelling intrinsic stochasticity inherent in many continuous-time physical processes. When such processes are observed in multiple individuals or experimental units,…

Computation · Statistics 2016-05-19 Gavin A. Whitaker , Andrew Golightly , Richard J. Boys , Chris Sherlock

Seismic inversion is crucial in hydrocarbon exploration, particularly for detecting hydrocarbons in thin layers. However, the detection of sparse thin layers within seismic datasets presents a significant challenge due to the ill-posed…

Image and Video Processing · Electrical Eng. & Systems 2024-01-10 Supriyo Chakraborty , Aurobinda Routray , Sanjay Bhargav Dharavath , Tanmoy Dam

In this paper a novel biclustering algorithm based on artificial intelligence (AI) is introduced. The method called EBIC aims to detect biologically meaningful, order-preserving patterns in complex data. The proposed algorithm is probably…

Machine Learning · Computer Science 2018-07-27 Patryk Orzechowski , Moshe Sipper , Xiuzhen Huang , Jason H. Moore

The identification of key populations shaping the structure and connectivity of metapopulation systems is a major challenge in population ecology. The use of molecular markers in the theoretical framework of population genetics has allowed…

Populations and Evolution · Quantitative Biology 2008-11-21 Alejandro F. Rozenfeld , Sophie Arnaud-Haond , Emilio Hernandez-Garcia , Victor M. Eguiluz , Ester A. Serrao , Carlos M. Duarte

The deployment of reconfigurable intelligent surfaces (RISs) in a communication system provides control over the propagation environment, which facilitates the augmentation of a multitude of communication objectives. As these performance…

Signal Processing · Electrical Eng. & Systems 2023-05-04 Bilal Ahmad , Kevin Weinberger , Aydin Sezgin , Bilal Zafar , Martin Haardt

Sparse autoencoders (SAEs) are a recent technique for decomposing neural network activations into human-interpretable features. However, in order for SAEs to identify all features represented in frontier models, it will be necessary to…

Machine Learning · Computer Science 2025-06-04 Anish Mudide , Joshua Engels , Eric J. Michaud , Max Tegmark , Christian Schroeder de Witt

Reconfigurable intelligent surface (RIS) is a promising candidate technology of the upcoming Sixth Generation (6G) communication system for its ability to provide unprecedented spectral and energy efficiency increment through passive…

Information Theory · Computer Science 2023-09-29 Haochen Li , Zhiwen Pan , Bin Wang , Nan Liu , Xiaohu You

Information about the structure and composition of biopsy specimens can assist in disease monitoring and diagnosis. In principle, this can be acquired from Raman and infrared (IR) hyperspectral images (HSIs) that encode information about…

Medical Physics · Physics 2022-09-12 Ciaran Bench , Jayakrupakar Nallala , Chun-Chin Wang , Hannah Sheridan , Nicholas Stone

Spatial epidemiology identifies the drivers of elevated population-level disease risks, using disease counts, exposures and known confounders at the areal unit level. Poisson regression models are typically used for inference, which…

Methodology · Statistics 2026-02-03 Duncan Lee , Vinny Davies

Microbiome researchers often need to model the temporal dynamics of multiple complex, nonlinear outcome trajectories simultaneously. This motivates our development of multivariate Sparse Functional Principal Components Analysis (mSFPCA),…

Massive multiple input and multiple output (MIMO) systems with orthogonal frequency division multiplexing (OFDM) are foundational for downlink multi-user (MU) communication in future wireless networks, for their ability to enhance spectral…

Signal Processing · Electrical Eng. & Systems 2025-07-30 Erdeng Zhang , Shuntian Zheng , Sheng Wu , Haoge Jia , Zhe Ji , Ailing Xiao

In this paper, we present two randomized distributed algorithms in wireless ad hoc networks. We consider that the network is structured into pairs of nodes (sender, receiver) in a decay space. We take into account the following: Each node…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-05-21 Aikaterini Nikolidaki

Sparse Mixture of Experts (SMoE) has emerged as a promising solution to achieving unparalleled scalability in deep learning by decoupling model parameter count from computational cost. By activating only a small subset of parameters per…

Machine Learning · Computer Science 2025-10-21 Minh-Khoi Nguyen-Nhat , Rachel S. Y. Teo , Laziz Abdullaev , Maurice Mok , Viet-Hoang Tran , Tan Minh Nguyen

Accurate electrochemical models are essential for the safe and efficient operation of lithium-ion batteries in real-world applications such as electrified vehicles and grid storage. Reduced-order models (ROM) offer a balance between…

Systems and Control · Electrical Eng. & Systems 2025-07-02 Samuel Filgueira da Silva , Mehmet Fatih Ozkan , Faissal El Idrissi , Marcello Canova

High-throughput data acquisition in synthetic biology leads to an abundance of data that need to be processed and aggregated into useful biological models. Building dynamical models based on this wealth of data is of paramount importance to…

Systems and Control · Computer Science 2018-09-25 Zoltan A. Tuza , Guy-Bart Stan

The growing availability of large and complex datasets has increased interest in temporal stochastic processes that can capture stylized facts such as marginal skewness, non-Gaussian tails, long memory, and even non-Markovian dynamics.…

Machine Learning · Statistics 2025-10-09 Dan Leonte , Raphaël Huser , Almut E. D. Veraart

Reconstructing the causal network in a complex dynamical system plays a crucial role in many applications, from sub-cellular biology to economic systems. Here we focus on inferring gene regulation networks (GRNs) from perturbation or gene…

Quantitative Methods · Quantitative Biology 2016-12-21 Hoi-To Wai , Anna Scaglione , Uzi Harush , Baruch Barzel , Amir Leshem
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