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We demonstrate that the information contained in the spike occurrence times of a population of neurons can be broken up into a series of terms, each of which reflect something about potential coding mechanisms. This is possible in the…

Biological Physics · Physics 2007-05-23 S. Panzeri , S. R. Schultz

We typically think of cells as responding to external signals independently by regulating their gene expression levels, yet they often locally exchange information and coordinate. Can such spatial coupling be of benefit for conveying…

Molecular Networks · Quantitative Biology 2015-01-19 Thomas R. Sokolowski , Gašper Tkačik

Neurons in the nervous system are submitted to distinct sources of noise, such as ionic-channel and synaptic noise, which introduces variability in their responses to repeated presentations of identical stimuli. This motivates the use of…

We consider a classical space-clamped Hodgkin-Huxley model neuron stimulated by synaptic excitation and inhibition with conductances represented by Ornstein-Uhlenbeck processes. Using numerical solutions of the stochastic model system…

Neurons and Cognition · Quantitative Biology 2016-04-19 Henry C. Tuckwell , Susanne Ditlevsen

We have studied neuronal synchronisation in a random network of adaptive exponential integrate-and-fire neurons. We study how spiking or bursting synchronous behaviour appears as a function of the coupling strength and the probability of…

Neuronal spiking exhibits an exquisite combination of modulation and robustness properties, rarely matched in artificial systems. We exploit the particular interconnection structure of conductance based models to investigate this remarkable…

Neurons and Cognition · Quantitative Biology 2013-11-12 Guillaume Drion , Alessio Franci , Vincent Seutin , Rodolphe Sepulchre

Excessively high, neural synchronisation has been associated with epileptic seizures, one of the most common brain diseases worldwide. A better understanding of neural synchronisation mechanisms can thus help control or even treat epilepsy.…

We propose an asynchronous iterative scheme that allows a set of interconnected nodes to distributively reach an agreement within a pre-specified bound in a finite number of steps. While this scheme could be adopted in a wide variety of…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-01-13 Andreas Grammenos , Themistoklis Charalambous , Evangelia Kalyvianaki

We report experimental studies of synchronization phenomena in a pair of biological neurons that interact through naturally occurring, electrical coupling. When these neurons generate irregular bursts of spikes, the natural coupling…

Solving constraint satisfaction problems (CSPs) is a notoriously expensive computational task. Recently, it has been proposed that efficient stochastic solvers can be obtained through appropriately configured spiking neural networks…

Neural and Evolutionary Computing · Computer Science 2016-04-07 Jonathan Binas , Giacomo Indiveri , Michael Pfeiffer

A formalism is developed which describes the extent to which stochastic oscillations in biochemical models are synchronised. It is based on the calculation of the complex coherence function within the linear noise approximation. The method…

Statistical Mechanics · Physics 2013-07-29 Joseph D. Challenger , Alan J. McKane

Neural activity in the brain of parkinsonian patients is characterized by the intermittently synchronized oscillatory dynamics. This imperfect synchronization, observed in the beta frequency band, is believed to be related to the…

Neurons and Cognition · Quantitative Biology 2013-02-11 Choongseok Park , Leonid Rubchinsky

Cortical circuits exhibit high levels of response diversity, even across apparently uniform neuronal populations. While emerging data-driven approaches exploit this heterogeneity to infer effective models of cortical circuit computation…

Neurons and Cognition · Quantitative Biology 2025-11-06 Mohammadreza Soltanipour , Stefan Treue , Fred Wolf

We address the problem of finding patterns from multi-neuronal spike trains that give us insights into the multi-neuronal codes used in the brain and help us design better brain computer interfaces. We focus on the synchronous firings of…

Neural and Evolutionary Computing · Computer Science 2010-06-09 Raajay Viswanathan , P. S. Sastry , K. P. Unnikrishnan

We propose a general approach to the question of how biological rhythms spontaneously self-regulate, based on the concept of ``stochastic feedback''. We illustrate this approach by considering the neuroautonomic regulation of the heart…

Statistical Mechanics · Physics 2009-10-30 Plamen Ch. Ivanov , Luis A. N. Amaral , Ary Goldberger , H. Eugene Stanley

Paced finger tapping is one of the simplest tasks to study sensorimotor synchronization. The subject is instructed to tap in synchrony with a periodic sequence of brief tones, and the time difference (called asynchrony) between each…

Neurons and Cognition · Quantitative Biology 2019-12-25 Claudia R. González , M. Luz Bavassi , Rodrigo Laje

Ordered and disordered behavior in large ensembles of coupled oscillators map to different functional states in a wide range of applications, e.g., active and resting states in the brain and stable and unstable power grid configurations.…

Adaptation and Self-Organizing Systems · Physics 2022-11-02 Can Xu , Xuan Wang , Per Sebastian Skardal

Neurons communicate with downstream systems via sparse and incredibly brief electrical pulses, or spikes. Using these events, they control various targets such as neuromuscular units, neurosecretory systems, and other neurons in connected…

Neurons and Cognition · Quantitative Biology 2026-03-17 Paolo Agliati , André Urbano , Pablo Lanillos , Nasir Ahmad , Marcel van Gerven , Sander Keemink

Brain encoding and decoding aims to understand the relationship between external stimuli and brain activities, and is a fundamental problem in neuroscience. In this article, we study latent embedding alignment for brain encoding and…

Methodology · Statistics 2026-03-24 Shuoxun Xu , Zhanhao Yan , Lexin Li

An essential step toward understanding neural circuits is linking their structure and their dynamics. In general, this relationship can be almost arbitrarily complex. Recent theoretical work has, however, begun to identify some broad…

Neurons and Cognition · Quantitative Biology 2017-03-10 Gabriel Koch Ocker , Yu Hu , Michael A. Buice , Brent Doiron , Krešimir Josić , Robert Rosenbaum , Eric Shea-Brown