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We present a detailed kinetic model for the Polymerase Chain Reaction, and model the probability of replication in terms of the physical parameters of the problem. Applying the theory of branching processes, we show the existance of a new…

Statistical Mechanics · Physics 2007-05-23 Guillermo A. Cecchi , Gustavo Stolovitzky

The phase structure of a homopolymer chain is investigated in terms of a universal theoretical model, designed to describe the infrared limit of slow spatial variations. The effects of chirality are studied and compared with the influence…

Soft Condensed Matter · Physics 2015-12-25 A. Sinelnikova , A. J. Niemi , M. Ulybyshev

We studied effects of random potentials and roles of electron-electron interactions in the gapless phase of coupled Hubbard chains, using a renormalization group technique. For non-interacting electrons, we obtained the localization length…

Strongly Correlated Electrons · Physics 2009-10-31 Hiroyuki Mori

Systems of interacting random replicators are studied using generating functional techniques. While replica analyses of such models are limited to systems with symmetric couplings, dynamical approaches as presented here allow specifically…

Disordered Systems and Neural Networks · Physics 2009-11-11 Tobias Galla

The self-avoid random walk algorithm has been extensively used in the study of polymers. In this work we study the basic properties of the trajectories generated with this algorithm when two interactions are added to it: contact and folding…

Soft Condensed Matter · Physics 2023-04-14 R. J. Santos Neto , A. A. Costa , P. F. Gomes

In this paper we consider a two-dimensional copolymer consisting of a random concatenation of hydrophobic and hydrophilic monomers near a linear interface separating oil and water acting as solvents. The configurations of the copolymer are…

Probability · Mathematics 2012-02-21 E. Bolthausen , F. den Hollander , A. A. Opoku

Elastic interaction of pressurized spherical cavities embedded in a three-dimensional hyperelastic medium is computationally analyzed. Using finite element analysis across several positive and negative pressure scenarios, we calculate the…

Soft Condensed Matter · Physics 2025-08-08 Ali Saeedi , Mrityunjay Kothari

While stretching of most polymer chains leads to rather featureless force-extension diagrams, some, notably DNA, exhibit non-trivial behavior with a distinct plateau region. Here we propose a unified theory that connects force-extension…

Mesoscale and Nanoscale Physics · Physics 2013-02-26 Alexander V. Savin , Mikhail A. Mazo , Irina P. Kikot , Alexey V. Onufriev

Herein, we describe new methods to produce colloidal particle chains of three stiffness regimes that can be observed on a single-particle level, that is, on the level of the monomers that make up the chain; the chains can even be observed…

We consider the Random Walk Pinning Model studied in [3,2]: this is a random walk X on Z^d, whose law is modified by the exponential of \beta times L_N(X,Y), the collision local time up to time N with the (quenched) trajectory Y of another…

Probability · Mathematics 2010-07-22 Q. Berger , F. Toninelli

We survey recent results and open questions on the ballistic phase of stretched polymers in both annealed and quenched random environments.

Probability · Mathematics 2018-04-26 Dmitry Ioffe , Yvan Velenik

We have performed fully atomistic classical molecular dynamics (MD) simulations to calculate the effective interaction between two polyamidoamine (PAMAM) dendrimers. Using the umbrella sampling (US) technique, we have obtained the potential…

Computational Physics · Physics 2015-06-23 Taraknath Mandal , Chandan Dasgupta , Prabal K Maiti

The mechanical properties of molecules are today captured by single molecule manipulation experiments, so that polymer features are tested at a nanometric scale. Yet devising mathematical models to get further insight beyond the commonly…

We have used kinetic Monte Carlo simulations to study the kinetics of unfolding of cross-linked polymer chains under mechanical loading. As the ends of a chain are pulled apart, the force transmitted by each crosslink increases until it…

Biological Physics · Physics 2009-11-10 Kilho Eom , Dmitrii E Makarov , Gregory J. Rodin

Average block entanglement in the 1D XX-model with uncorrelated random couplings is known to grow as the logarithm of the block size, in similarity to conformal systems. In this work we study random spin chains whose couplings present long…

Statistical Mechanics · Physics 2016-07-19 Javier Rodríguez-Laguna , Silvia N. Santalla , Giovanni Ramírez , Germán Sierra

We present a statistical mechanical study of stiff polymers, motivated by experiments on actin filaments and the considerable current interest in polymer networks. We obtain simple, approximate analytical forms for the force-extension…

Soft Condensed Matter · Physics 2009-11-13 Abhijit Ghosh , Joseph Samuel , Supurna Sinha

The non-equilibrium structural and dynamical properties of a flexible polymer tethered to a reflecting wall and subject to oscillatory linear flow are studied by numerical simulations. Polymer is confined in two dimensions and is modeled as…

Soft Condensed Matter · Physics 2024-07-30 A. Lamura

Nano-scale confinement of polymer in cone-shaped geometries occurs in many experimental situations. A flexible polymer confined in a cone-shaped nano-channel is studied theoretically and using molecular dynamics simulations. Distribution of…

Soft Condensed Matter · Physics 2016-02-24 Narges Nikoofard , Hossein Fazli

We present an exactly solvable model of a Gaussian (flexible) polymer chain in a quenched random medium. This is the case when the random medium obeys very long range quadratic correlations. The model is solved in $d$ spatial dimensions…

Disordered Systems and Neural Networks · Physics 2009-10-31 Yohannes Shiferaw , Yadin Y. Goldschmidt

We explore the elastic behavior of a wormlike chain under compression in terms of exact solutions for the associated probability densities. Strikingly, the probability density for the end-to-end distance projected along the applied force…

Soft Condensed Matter · Physics 2019-11-11 Christina Kurzthaler , Thomas Franosch