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The area under the ROC curve is widely used as a measure of performance of classification rules. However, it has recently been shown that the measure is fundamentally incoherent, in the sense that it treats the relative severities of…

Methodology · Statistics 2013-08-02 David J. Hand , Christoforos Anagnostopoulos

Covariate adjustment is a ubiquitous method used to estimate the average treatment effect (ATE) from observational data. Assuming a known graphical structure of the data generating model, recent results give graphical criteria for optimal…

Statistics Theory · Mathematics 2025-12-08 Alexander Mangulad Christgau , Anton Rask Lundborg , Niels Richard Hansen

Permutation tests are widely used for statistical hypothesis testing when the sampling distribution of the test statistic under the null hypothesis is analytically intractable or unreliable due to finite sample sizes. One critical challenge…

Computation · Statistics 2023-08-29 Yang Shi , Huining Kang , Ji-Hyun Lee , Hui Jiang

Given a graph where every node has certain attributes associated with it and some nodes have labels associated with them, Collective Classification (CC) is the task of assigning labels to every unlabeled node using information from the node…

Machine Learning · Computer Science 2018-11-14 Priyesh Vijayan , Yash Chandak , Mitesh M. Khapra , Srinivasan Parthasarathy , Balaraman Ravindran

The odds ratio (OR) is a measure of effect size commonly used in observational research. OR reflects statistical association between a binary outcome, such as the presence of a health condition, and a binary predictor, such as an exposure…

Methodology · Statistics 2018-07-09 Olga A Vsevolozhskaya , Dmitri V Zaykin

The receiver operating characteristic (ROC) curve is a very useful tool for analyzing the diagnostic/classification power of instruments/classification schemes as long as a binary-scale gold standard is available. When the gold standard is…

Methodology · Statistics 2011-05-10 Zhanfeng Wang , Yuan-chin Ivan Chang

This work proposes a new method for computing acceptance regions of exact multinomial tests. From this an algorithm is derived, which finds exact p-values for tests of simple multinomial hypotheses. Using concepts from discrete convex…

Computation · Statistics 2023-05-31 Johannes Resin

Robust Ordinal Regression (ROR) is a way of dealing with Multiple Criteria Decision Aiding (MCDA), by considering all sets of parameters of an assumed preference model, that are compatible with preference information given by the Decision…

Optimization and Control · Mathematics 2012-06-28 Salvatore Corrente , Salvatore Greco , Roman Slowinski

Statistical testing is classically used as an exploratory tool to search for association between a phenotype and many possible explanatory variables. This approach often leads to multiple testing under dependence. We assume a hierarchical…

Applications · Statistics 2021-09-28 Antoine Bichat , Christophe Ambroise , Mahendra Mariadassou

In a case-control study aimed at locating autosomal disease variants for a disease of interest, association between markers and the disease status is often tested by comparing the marker minor allele frequencies (MAFs) between cases and…

Applications · Statistics 2020-02-13 Marianne A. Jonker , Jakub Pecanka

Analyses of population-based surveys are instrumental to research on prevention and treatment of mental and substance use disorders. Population-based data provides descriptive characteristics of multiple determinants of public health and…

Methodology · Statistics 2020-07-03 Olga A. Vsevolozhskaya , Karl C. Alcover , James C. Anthony , Dmitri V. Zaykin

Background. Many mutation reduction strategies, which aim to reduce the number of mutants, have been proposed. Problem. It is important to measure the ability of a mutation reduction strategy to maintain test suite effectiveness evaluation.…

Software Engineering · Computer Science 2021-02-08 Peng Zhang , Yang Wang , Xutong Liu , Yanhui Li , Yibao Yang , Ziyuan Wang , Xiaoyu Zhou , Lin Chen , Yuming Zhou

A recently popular approach to solving reinforcement learning is with data from human preferences. In fact, human preference data are now used with classic reinforcement learning algorithms such as actor-critic methods, which involve…

Machine Learning · Computer Science 2024-02-28 Zihao Li , Xiang Ji , Minshuo Chen , Mengdi Wang

Testing for the significance of a subset of regression coefficients in a linear model, a staple of statistical analysis, goes back at least to the work of Fisher who introduced the analysis of variance (ANOVA). We study this problem under…

Statistics Theory · Mathematics 2012-02-24 Ery Arias-Castro , Emmanuel J. Candès , Yaniv Plan

Propensity scores are often used for stratification of treatment and control groups of subjects in observational data to remove confounding bias when estimating of causal effect of the treatment on an outcome in so-called potential outcome…

Statistics Theory · Mathematics 2018-04-24 Priyantha Wijayatunga

There is a growing interest in using a longitudinal observational databases to detect drug safety signal. In this paper we present a novel method, which we used online during the OMOP Cup. We consider homogeneous ensembling, which is based…

Machine Learning · Statistics 2011-10-05 Vladimir Nikulin

Standardization has been a widely adopted practice in multiple testing, for it takes into account the variability in sampling and makes the test statistics comparable across different study units. However, despite conventional wisdom to the…

Methodology · Statistics 2020-03-09 Luella Fu , Bowen Gang , Gareth M. James , Wenguang Sun

Thanks to its favorable properties, the multivariate normal distribution is still largely employed for modeling phenomena in various scientific fields. However, when the number of components $p$ is of the same asymptotic order as the sample…

Statistics Theory · Mathematics 2022-11-17 Caizhu Huang , Claudia Di Caterina , Nicola Sartori

The co-sparse analysis model for signals assumes that the signal of interest can be multiplied by an analysis dictionary \Omega, leading to a sparse outcome. This model stands as an interesting alternative to the more classical synthesis…

Information Theory · Computer Science 2012-03-14 Tomer Peleg , Michael Elad

While a large body of research has formally identified apolipoprotein E (APOE) as a major genetic risk marker for Alzheimer disease, accumulating evidence supports the notion that other risk markers may exist. The traditional…

Quantitative Methods · Quantitative Biology 2020-03-13 Ning An , Liuqi Jin , Huitong Ding , Jiaoyun Yang , Jing Yuan