Related papers: Optimizing control of HIV in Kenya

Accurate HIV incidence estimation based on individual recent infection status (recent vs long-term infection) is important for monitoring the epidemic, targeting interventions to those at greatest risk of new infection, and evaluating…

In this paper, we construct a model to describe the transmission of HIV in a homogeneous host population. By considering the specific mechanism of HIV, we derive a model structured in three successive stages: (i) primary infection, (ii)…

In this article, we propose a network spread model for HIV epidemics, wherein each individual is represented by a node of the transmission network and the edges are the connections between individuals along which the infection may spread.…

Background: Approximately 40% of adults in Botswana are HIV-infected. The Botswana antiretroviral program began in 2002 and currently treats 34,000 patients with a goal of treating 85,000 patients (~30% of HIV-infected adults) by 2009. We…

Cross-sectional HIV incidence estimation leverages recency test results to determine the HIV incidence of a population of interest, where recency test uses biomarker profiles to infer whether an HIV-positive individual was "recently"…

Pre-exposure prophylaxis (PrEP) consists in the use of an antiretroviral medication to prevent the acquisition of HIV infection by uninfected individuals and has recently demonstrated to be highly efficacious for HIV prevention. We propose…

In a recent article Hontelez and colleagues investigate the prospects for elimination of HIV in South Africa through expanded access to antiretroviral therapy (ART) using STDSIM, a micro-simulation model. One of the first published models…

Access to combination antiretroviral treatment (ART) has improved greatly over recent years. At the end of 2011, more than eight million HIV infected people were receiving antiretroviral therapy in low-income and middle-income countries.…

Background: After a decade of a treatment as prevention (TasP) strategy based on progressive HIV testing scale-up and earlier treatment, a reduction in the estimated number of new infections in men-who-have-sex-with-men (MSM) in England had…

The United Nations (UN) issued official probabilistic population projections for all countries to 2100 in July 2015. This was done by simulating future levels of total fertility and life expectancy from Bayesian hierarchical models, and…

A mental health disorder is a clinically significant impairment in a persons intellect, emotional control, or behavior. Mental disorders and outpatient morbidity are a challenge to public health in Kenya. The spatial distribution and study…

Ending the HIV/AIDS pandemic is among the Sustainable Development Goals for the next decade. In order to overcome the gap between the need for care and the available resources, better understanding of HIV epidemics is needed to guide policy…

In August 2020, the World Health Assembly approved the Global Strategy to eliminate cervical cancer, marking the first time that numerous countries committed to eliminating a form of cancer. China introduced the HPV vaccine in 2016 and has…

Each year, there are nearly 4 million youth experiencing homelessness (YEH) in the United States with HIV prevalence ranging from 3 to 11.5%. Peer change agent (PCA) models for HIV prevention have been used successfully in many populations,…

As the global HIV pandemic enters its fourth decade, increasing numbers of surveillance sites have been established which allows countries to look into the epidemics at a finer scale, e.g. at sub-national level. However, the epidemic models…

The Joint United Nations Programme on HIV/AIDS (UNAIDS) has developed the Estimation and Projection Package (EPP) for making national estimates and short-term projections of HIV prevalence based on observed prevalence trends at antenatal…

In this article, we consider an HIV/AIDS epidemic model with four classes of individuals. We have discussed about basic properties of the system and found the basic reproduction number $R_0$ of the system. The stability analysis of the…

Estimating new HIV infections is significant yet challenging due to the difficulty in distinguishing between recent and long-term infections. We demonstrate that HIV recency status (recent v.s. long-term) could be determined from the…

Random mixing in host populations has been a convenient simplifying assumption in the study of epidemics, but neglects important differences in contact rates within and between population groups. For HIV/AIDS, the assumption of random…

In most countries CD4+ cell counts are still used for deciding when to start HIV-positive people on anti-retroviral therapy. However, various CD4+ thresholds, 200, 350 or 500/\muL, are chosen arbitrarily and for historical reasons. Here we…