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Essentially all biology is active and dynamic. Biological entities autonomously sense, com- pute, and respond using energy-coupled ratchets that can produce force and do work. The cytoskeleton, along with its associated proteins and motors,…

Soft Condensed Matter · Physics 2017-03-28 Kasimira T. Stanhope , Vikrant Yadav , Christian D. Santangelo , Jennifer L. Ross

In amorphous solids as in tissues, neighbor exchanges can relax local stresses and allow the material to flow. In this paper, we use an anisotropic vertex model to study T1 rearrangements in polygonal cellular networks. We consider two…

Biological Physics · Physics 2022-11-11 Charlie Duclut , Joris Paijmans , Mandar M. Inamdar , Carl D. Modes , Frank Jülicher

We present a combined numerical and analytical study of pattern formation in an active system where particles align, possess a density-dependent motility, and are subject to a logistic reaction. This is a model for suspensions of…

Soft Condensed Matter · Physics 2015-06-16 X. Yang , D. Marenduzzo , M. C. Marchetti

Cytoskeletal networks, which are essentially motor-filament assemblies, play a major role in many developmental processes involving structural remodeling and shape changes. These are achieved by nonequilibrium self-organization processes…

Soft Condensed Matter · Physics 2014-12-22 Shenshen Wang , Peter G. Wolynes

In this paper, we develop and analyze a minimal model for a 2D network of cross-linked actin filaments and myosin motors, representing the cortical cytoskeleton of eukaryotic cells. We implement coarse-grained representations of force…

Subcellular Processes · Quantitative Biology 2016-12-23 William M. McFadden , Patrick M. McCall , Edwin M. Munro

Rheological responses are the most relevant features to describe soft matter. So far, such constitutive relations are still not well understood in terms of small scale properties, although this knowledge would help the design of synthetic…

Soft Condensed Matter · Physics 2020-08-12 J. L. B. de Araujo , J. S. de Sousa , W. P. Ferreira , C. L. N. Oliveira

Signatures of glassy dynamics have been identified experimentally for a rich variety of materials in which molecular networks provide rigidity. Here we present a theoretical framework to study the glassy behavior of both passive and active…

Statistical Mechanics · Physics 2013-03-26 Shenshen Wang , Peter G. Wolynes

There is a growing interest in producing materials with mechanical behaviours similar to those of internal organs. An artificial tissue may be expected to experience several types of compressive and shear deformation in the course of normal…

Applied Physics · Physics 2018-01-01 Utkarsh Jain

Active stresses, which are collectively generated by the motion of energy-consuming rod-like constituents, generate chaotic autonomous flows. Controlling active stresses in space and time is an essential prerequisite for controlling the…

Soft Condensed Matter · Physics 2022-09-15 Linnea M. Lemma , Minu Varghese , Tyler D. Ross , Matt Thomson , Aparana Baskaran , Zvonimir Dogic

We have studied the elastic response of actin networks with both compliant and rigid crosslinks by modeling molecular motors as force dipoles. Our finite element simulations show that for compliant crosslinkers such as filamin A, the…

Soft Condensed Matter · Physics 2010-09-06 Peng Chen , Vivek B. Shenoy

Mechanical densification of granular bodies is a process in which a loose material becomes increasingly cohesive as the applied pressure increases. A constitutive description of this process faces the formidable problem that granular and…

Mathematical Physics · Physics 2015-05-20 Andrea Piccolroaz , Davide Bigoni , Alessandro Gajo

This study addresses the modelling of elastic bodies, particularly when the relaxed configuration is unknown or non-existent. We adopt the theory of initially stressed materials, incorporating the deformation gradient and stress state of…

Soft Condensed Matter · Physics 2024-11-28 M. Magri , D. Riccobelli

Active processes in living systems generate nonequilibrium forces that deform embedded passive macromolecules. To understand how such dynamics influence polymer conformation, we study a flexible passive chain in an active nematic fluid.…

Soft Condensed Matter · Physics 2025-09-30 Zahra K. Valei , Davide Marenduzzo , Tyler N. Shendruk

I put forward a continuum theory for active nematic gels, defined as fluids or suspensions of orientable rodlike objects endowed with active dynamics, that is based on symmetry arguments and compatibility with thermodynamics. The starting…

Soft Condensed Matter · Physics 2017-11-15 Stefano S Turzi

Mixtures of microtubules and molecular motors form active materials with diverse dynamical behaviors that vary based on their constituents' molecular properties. We map the non-equilibrium phase diagram of microtubules and tip-accumulating…

Soft Condensed Matter · Physics 2021-08-04 Bezia Lemma , Noah P. Mitchell , Radhika Subramanian , Daniel J. Needleman , Zvonimir Dogic

We propose a general hybrid physics-informed machine learning framework for modeling nonlinear, history-dependent viscoelastic behavior under multiaxial cyclic loading. The approach is built on a generalized internal state variable-based…

Soft Condensed Matter · Physics 2025-07-18 Alireza Ostadrahimi , Amir Teimouri , Kshitiz Upadhyay , Guoqiang Li

We propose a new model to describe diffusion processes within active deformable media. Our general theoretical framework is based on physical and mathematical considerations, and it suggests to use diffusion tensors directly coupled to…

Tissues and Organs · Quantitative Biology 2021-03-03 Christian Cherubini , Simonetta Filippi , Alessio Gizzi , Ricardo Ruiz-Baier

Living matter moves, deforms, and organizes itself. In cells this is made possible by networks of polymer filaments and crosslinking molecules that connect filaments to each other and that act as motors to do mechanical work on the network.…

Soft Condensed Matter · Physics 2020-12-15 Sebastian Fürthauer , Daniel J Needleman , Michael J. Shelley

Architected materials that exploit buckling instabilities to reversibly trap energy have been shown to be effective for impact protection. The energy-absorbing capabilities of these architected materials can be enhanced further by…

Soft Condensed Matter · Physics 2026-01-09 Beijun Shen , Yuefeng Jiang , Christopher M. Yakacki , Sung Hoon Kang , Thao D. Nguyen

Structure formation and constant reorganization of the actin cytoskeleton are key requirements for the function of living cells. Here we show that a minimal reconstituted system consisting of actin filaments, crosslinking molecules and…

Biological Physics · Physics 2015-05-27 Simone Köhler , Volker Schaller , Andreas R. Bausch
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