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To facilitate rational molecular and materials design, this research proposes an integrated computational framework that combines stochastic simulation, ab initio quantum chemistry, and molecular docking. The suggested workflow allows…

Materials Science · Physics 2026-01-08 Md Rakibul Karim Akanda , Michael P. Richard

Face modeling has been paid much attention in the field of visual computing. There exist many scenarios, including cartoon characters, avatars for social media, 3D face caricatures as well as face-related art and design, where low-cost…

Graphics · Computer Science 2017-06-08 Xiaoguang Han , Chang Gao , Yizhou Yu

Sketching in 3D space enables expressive reasoning about shape, structure, and spatial relationships, yet generating 3D sketches through natural language remains a major challenge. In this work, we introduce 3DrawAgent, a training-free,…

Computer Vision and Pattern Recognition · Computer Science 2026-04-10 Hongcan Xiao , Xinyue Xiao , Yilin Wang , Yue Zhang , Yonggang Qi

People naturally sketch strokes over graphical scenes to convey scene changes. We propose automatically interpreting these strokes to execute scene changes with squidgets (sketch-widgets), a novel sketch-based UI framework for direct scene…

Graphics · Computer Science 2026-05-22 Joonho Kim , Fanny Chevalier , Karan Singh

Text-to-motion generation, which translates textual descriptions into human motions, has been challenging in accurately capturing detailed user-imagined motions from simple text inputs. This paper introduces StickMotion, an efficient…

Computer Vision and Pattern Recognition · Computer Science 2025-03-10 Tao Wang , Zhihua Wu , Qiaozhi He , Jiaming Chu , Ling Qian , Yu Cheng , Junliang Xing , Jian Zhao , Lei Jin

3D Content Generation is at the heart of many computer graphics applications, including video gaming, film-making, virtual and augmented reality, etc. This paper proposes a novel deep-learning based approach for automatically generating…

Computer Vision and Pattern Recognition · Computer Science 2026-02-09 Yongzhi Xu , Yonhon Ng , Yifu Wang , Inkyu Sa , Yunfei Duan , Zhenhong Sun , Yang Li , Pan Ji , Hongdong Li

Proteins are the fundamental macromolecules that play diverse and crucial roles in all living matter and have tremendous implications in healthcare, manufacturing, and biotechnology. Their functions are largely determined by the sequences…

Biomolecules · Quantitative Biology 2024-09-17 Boqiao Lai

Our understanding of the physics of biological molecules, such as proteins and DNA, is limited because the approximations we usually apply to model inert materials are not in general applicable to soft, chemically inhomogeneous systems. The…

Quantum Physics · Physics 2010-07-13 Sarah Harris , Vivien M. Kendon

Biochars have been attracting renewed attention as economical and environmentally friendly carbon sequestration materials with a diverse range of applications. However, experimental developments may be limited by the lack of molecular-level…

Materials Science · Physics 2024-06-11 Rosie Wood , Ondrej Masek , Valentina Erastova

Design mockups are essential instruments for visualizing and testing design ideas. However, the process of generating mockups can be time-consuming and challenging for designers. In this article, we present and evaluate two different…

Human-Computer Interaction · Computer Science 2023-03-23 Tommaso Calò , Luigi De Russis

The discovery of new materials has been the essential force which brings a discontinuous improvement to industrial products' performance. However, the extra-vast combinatorial design space of material structures exceeds human experts'…

We study a fundamental problem in structure-based drug design -- generating molecules that bind to specific protein binding sites. While we have witnessed the great success of deep generative models in drug design, the existing methods are…

Biomolecules · Quantitative Biology 2022-11-15 Shitong Luo , Jiaqi Guan , Jianzhu Ma , Jian Peng

This article proposes a novel computational modeling approach for short-ranged molecular interactions between curved slender fibers undergoing large 3D deformations, and gives a detailed overview how it fits into the framework of existing…

Computational Engineering, Finance, and Science · Computer Science 2022-08-19 Maximilian J. Grill , Wolfgang A. Wall , Christoph Meier

The technology to capture, create, and use three-dimensional (3D) models has become increasingly accessible in recent years. With increasing numbers of use cases for 3D models and collections of rapidly increasing size, better methods to…

Multimedia · Computer Science 2024-07-25 Florian Spiess , Raphael Waltenspül , Heiko Schuldt

Machine learning has emerged as a powerful tool in materials discovery, enabling the rapid design of novel materials with tailored properties for countless applications, including in the context of energy and sustainability. To ensure the…

The discovery of functional molecules is an expensive and time-consuming process, exemplified by the rising costs of small molecule therapeutic discovery. One class of techniques of growing interest for early-stage drug discovery is de novo…

Quantitative Methods · Quantitative Biology 2020-02-18 Wenhao Gao , Connor W. Coley

Sketch animations offer a powerful medium for visual storytelling, from simple flip-book doodles to professional studio productions. While traditional animation requires teams of skilled artists to draw key frames and in-between frames,…

Graphics · Computer Science 2024-11-19 Hmrishav Bandyopadhyay , Yi-Zhe Song

Creating custom artifacts with computer numerical control (CNC) milling machines typically requires mastery of complex computer-aided design (CAD) software. To eliminate this user barrier, we introduced Draw2Cut, a novel system that allows…

Human-Computer Interaction · Computer Science 2025-04-29 Xinyue Gui , Ding Xia , Wang Gao , Mustafa Doga Dogan , Maria Larsson , Takeo Igarashi

Recent advances in electron microscopy have enabled the imaging of single cells in 3D at nanometer length scale resolutions. An uncharted frontier for in silico biology is the ability to simulate cellular processes using these observed…

We propose GroundUp, the first sketch-based ideation tool for 3D city massing of urban areas. We focus on early-stage urban design, where sketching is a common tool and the design starts from balancing building volumes (masses) and open…

Computer Vision and Pattern Recognition · Computer Science 2024-07-18 Gizem Esra Unlu , Mohamed Sayed , Yulia Gryaditskaya , Gabriel Brostow
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