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Chemical reaction networks (CRNs) provide a convenient language for modelling a broad variety of biological systems. These models are commonly studied with respect to the time series they generate in deterministic or stochastic simulations.…

Molecular Networks · Quantitative Biology 2019-07-11 Ozan Kahramanoğulları

Graph Neural Networks (GNNs) have emerged as powerful representation learning tools for capturing complex dependencies within diverse graph-structured data. Despite their success in a wide range of graph mining tasks, GNNs have raised…

Machine Learning · Computer Science 2024-06-19 Wenzhao Jiang , Hao Liu , Hui Xiong

Gene-environment interactions have important implications to elucidate the genetic basis of complex diseases beyond the joint function of multiple genetic factors and their interactions (or epistasis). In the past, G$\times$E interactions…

Applications · Statistics 2020-03-09 Fei Zhou , Jie Ren , Xi Lu , Shuangge Ma , Cen Wu

"Mixed Data" comprising a large number of heterogeneous variables (e.g. count, binary, continuous, skewed continuous, among other data types) are prevalent in varied areas such as genomics and proteomics, imaging genetics, national…

Statistics Theory · Mathematics 2014-11-04 Eunho Yang , Pradeep Ravikumar , Genevera I. Allen , Yulia Baker , Ying-Wooi Wan , Zhandong Liu

Graph data structures offer a versatile and powerful means to model relationships and interconnections in various domains, promising substantial advantages in data representation, analysis, and visualization. In games, graph-based data…

Machine Learning · Computer Science 2024-09-10 Florian Rupp , Kai Eckert

In this work we introduce a fully-connected graph structure in the Deep Gaussian Conditional Random Field (G-CRF) model. For this we express the pairwise interactions between pixels as the inner-products of low-dimensional embeddings,…

Computer Vision and Pattern Recognition · Computer Science 2016-11-29 Siddhartha Chandra , Iasonas Kokkinos

The concept of multilayer networks has become recently integrated into complex systems modeling since it encapsulates a very general concept of complex relationships. Biological pathways are an example of complex real-world networks, where…

Human-Computer Interaction · Computer Science 2021-10-12 Hsiang-Yun Wu , Martin Nöllenburg , Ivan Viola

A graphical model is a statistical model that is associated to a graph whose nodes correspond to variables of interest. The edges of the graph reflect allowed conditional dependencies among the variables. Graphical models admit…

Methodology · Statistics 2016-06-09 Mathias Drton , Marloes H. Maathuis

Visual dynamic complexity is a ubiquitous, hidden attribute of the visual world that every dynamic vision system is faced with. However, it is implicit and intractable which has never been quantitatively described due to the difficulty in…

Robotics · Computer Science 2021-05-21 Qinbing Fu , Tian Liu , Xuelong Sun , Huatian Wang , Jigen Peng , Shigang Yue , Cheng Hu

Neural network design has utilized flexible nonlinear processes which can mimic biological systems, but has suffered from a lack of traceability in the resulting network. Graphical probabilistic models ground network design in probabilistic…

Machine Learning · Computer Science 2015-06-19 Kenric P. Nelson , Madalina Barbu , Brian J. Scannell

Randomized controlled trials are not only the golden standard in medicine and vaccine trials but have spread to many other disciplines like behavioral economics, making it an important interdisciplinary tool for scientists. When designing…

Methodology · Statistics 2021-11-30 Tassilo Schwarz

The problem of learning the structure of a high dimensional graphical model from data has received considerable attention in recent years. In many applications such as sensor networks and proteomics it is often expensive to obtain samples…

Machine Learning · Statistics 2016-04-08 Gautam Dasarathy , Aarti Singh , Maria-Florina Balcan , Jong Hyuk Park

Genomics has revolutionized biology, enabling the interrogation of whole transcriptomes, genome-wide binding sites for proteins, and many other molecular processes. However, individual genomic assays measure elements that interact in vivo…

Machine Learning · Statistics 2022-06-08 Sumanta Basu , Karl Kumbier , James B. Brown , Bin Yu

Random forests are a machine learning method used to automatically classify datasets and consist of a multitude of decision trees. While these random forests often have higher performance and generalize better than a single decision tree,…

Machine Learning · Computer Science 2025-07-31 Max Sondag , Christofer Meinecke , Dennis Collaris , Tatiana von Landesberger , Stef van den Elzen

Knowing the features of a complex system that are highly relevant to a particular target variable is of fundamental interest in many areas of science. Existing approaches are often limited to linear settings, sometimes lack guarantees, and…

Machine Learning · Computer Science 2023-07-06 Francesco Quinzan , Ashkan Soleymani , Patrick Jaillet , Cristian R. Rojas , Stefan Bauer

A conditional independence graph is a concise representation of pairwise conditional independence among many variables. Graphical Random Forests (GRaFo) are a novel method for estimating pairwise conditional independence relationships among…

We focus on the problem of streaming recommender system and explore novel collaborative filtering algorithms to handle the data dynamicity and complexity in a streaming manner. Although deep neural networks have demonstrated the…

Machine Learning · Computer Science 2019-06-12 Qingquan Song , Shiyu Chang , Xia Hu

Current genomic foundation models (GFMs) rely on extensive neural computation to implicitly approximate conserved biological motifs from single-nucleotide inputs. We propose Gengram, a conditional memory module that introduces an explicit…

Electronic Theses and Dissertations (ETDs) contain domain knowledge that can be used for many digital library tasks, such as analyzing citation networks and predicting research trends. Automatic metadata extraction is important to build…

Digital Libraries · Computer Science 2021-07-02 Muntabir Hasan Choudhury , Himarsha R. Jayanetti , Jian Wu , William A. Ingram , Edward A. Fox

Data-based discovery of effective, coarse-grained (CG) models of high-dimensional dynamical systems presents a unique challenge in computational physics and particularly in the context of multiscale problems. The present paper offers a…

Computational Physics · Physics 2020-08-26 Sebastian Kaltenbach , Phaedon-Stelios Koutsourelakis