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Many population genetic models have been developed for the purpose of inferring population size and growth rates from random samples of genetic data. We examine two popular approaches to this problem, the coalescent and the…

Populations and Evolution · Quantitative Biology 2014-08-29 Erik M. Volz , Simon DW Frost

Contemporary modeling approaches to the dynamics of neural networks consider two main classes of models: biologically grounded spiking neurons and functionally inspired rate-based units. The unified simulation framework presented here…

Neurons and Cognition · Quantitative Biology 2017-11-27 Jan Hahne , David Dahmen , Jannis Schuecker , Andreas Frommer , Matthias Bolten , Moritz Helias , Markus Diesmann

Multi-model inference covers a wide range of modern statistical applications such as variable selection, model confidence set, model averaging and variable importance. The performance of multi-model inference depends on the availability of…

Statistics Theory · Mathematics 2019-06-07 Ching-Wei Cheng , Guang Cheng

Recombination is an important event in the evolution of HIV. It affects the global spread of the pandemic as well as evolutionary escape from host immune response and from drug therapy within single patients. Comprehensive computational…

Genomics · Quantitative Biology 2007-05-23 Niko Beerenwinkel , Colin N. Dewey , Kevin M. Woods

The conditionally Markov (CM) sequence contains different classes, including Markov, reciprocal, and so-called $CM_L$ and $CM_F$ (two CM classes defined in our previous work). Markov sequences are special reciprocal sequences, and…

Systems and Control · Electrical Eng. & Systems 2020-06-09 Reza Rezaie , X. Rong Li

Sequential importance sampling algorithms have been defined to estimate likelihoods in models of ancestral population processes. However, these algorithms are based on features of the models with constant population size, and become…

Statistics Theory · Mathematics 2016-03-24 Coralie Merle , Raphaël Leblois , François Rousset , Pierre Pudlo

We propose a Bayesian inference approach for a class of latent Markov models. These models are widely used for the analysis of longitudinal categorical data, when the interest is in studying the evolution of an individual unobservable…

Methodology · Statistics 2011-01-05 Francesco Bartolucci , Silvia Pandolfi

We develop a practical approach to establish the stability, that is, the recurrence in a given set, of a large class of controlled Markov chains. These processes arise in various areas of applied science and encompass important numerical…

Statistics Theory · Mathematics 2015-02-02 Christophe Andrieu , Vladislav B. Tadić , Matti Vihola

The paper deals with a certain class of random evolutions. We develop a construction that yields an invariant measure for a continuous-time Markov process with random transitions. The approach is based on a particular way of constructing…

Probability · Mathematics 2015-10-20 Y. Belopolskaya , Y. Suhov

We find an advantage of recombination for a category of complex fitness landscapes. Recent studies of empirical fitness landscapes reveal complex gene interactions and multiple peaks, and recombination can be a powerful mechanism for…

Populations and Evolution · Quantitative Biology 2014-11-10 Kristina Crona

Quantitative social science is not only about regression analysis or, in general, data inference. Computer simulations of social mechanisms have a 60-year long history. They have been used for many different purposes -- to test scenarios,…

Physics and Society · Physics 2021-10-01 Petter Holme , Fredrik Liljeros

The study of time-inhomogeneous Markov jump processes is a traditional topic within probability theory that has recently attracted substantial attention in various applications. However, their flexibility also incurs a substantial…

Probability · Mathematics 2023-11-03 Martin Bladt , Oscar Peralta

The spatial symmetry property of truncated birth-death processes studied in Di Crescenzo [6] is extended to a wider family of continuous-time Markov chains. We show that it yields simple expressions for first-passage-time densities and…

Probability · Mathematics 2007-05-23 Antonio Di Crescenzo , Annapatrizia Nastro

Hybrid systems, and Piecewise Deterministic Markov Processes in particular, are widely used to model and numerically study systems exhibiting multiple time scales in biochemical reaction kinetics and related areas. In this paper an almost…

Numerical Analysis · Mathematics 2011-12-07 Martin G. Riedler

Consider two ancestral lineages sampled from a system of two-dimensional branching random walks with logistic regulation in the stationary regime. We study the asymptotics of their coalescence time for large initial separation and find that…

Probability · Mathematics 2024-05-06 Matthias Birkner , Andrej Depperschmidt , Timo Schlüter

State-space models (SSM) with Markov switching offer a powerful framework for detecting multiple regimes in time series, analyzing mutual dependence and dynamics within regimes, and asserting transitions between regimes. These models…

Methodology · Statistics 2021-06-14 David Degras , Chee-Ming Ting , Hernando Ombao

Simulation models are an absolute necessity in the human and social sciences, which can only very exceptionally use experimental science methods to construct their knowledge. Models enable the simulation of social processes by replacing the…

Computers and Society · Computer Science 2020-01-06 J. Raimbault , D. Pumain

Repetitions within a given genealogical tree provides some information about the degree of consanguineity of a population. They can be analyzed with techniques usually employed in statistical physics when dealing with fixed point…

Statistical Mechanics · Physics 2009-10-31 Paolo De Los Rios , Oscar Pla

Statistical inference about the speciation process has often been based on the isolation-with-migration (IM) model, especially when the research aim is to learn about the presence or absence of gene flow during divergence. The generalised…

Populations and Evolution · Quantitative Biology 2016-02-05 Rui J. Costa , Hilde Wilkinson-Herbots

Herein, we introduce and study a new class of discrete random fields designed for quick simulation and covariance inference under inhomogeneous condition. Simulation of these correlated fields can be done in a single pass instead of relying…

Probability · Mathematics 2012-12-05 Biao Wu , Michael A. Kouritzin , Fraser Newton