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Alignment algorithms usually rely on simplified models of gaps for computational efficiency. Based on an isomorphism between alignments and physical helix-coil models, we show in statistical mechanics that alignments with realistic laws for…

Genomics · Quantitative Biology 2015-06-26 E. Yeramian , E. Debonneuil

Models characterized by autoregressive structure and random coefficients are powerful tools for the analysis of high-frequency, high-dimensional and volatile time series. The available literature on such models is broad, but also sectorial,…

Methodology · Statistics 2020-09-18 Marta Regis , Paulo Serra , Edwin R. van den Heuvel

We discuss several algorithms for sampling from unnormalized probability distributions in statistical physics, but using the language of statistics and machine learning. We provide a self-contained introduction to some key ideas and…

Computation · Statistics 2025-05-05 Michael F. Faulkner , Samuel Livingstone

We provide a set of conditions which ensure the almost sure convergence of a class of simulated annealing algorithms on a bounded set $\mathcal{X}\subset\mathbb{R}^d$ based on a time-varying Markov kernel. The class of algorithms considered…

Probability · Mathematics 2017-07-07 Mathieu Gerber , Luke Bornn

Modeling joint probability distributions is an important task in a wide variety of fields. One popular technique for this employs a family of multivariate distributions with uniform marginals called copulas. While the theory of modeling…

We introduce statistical techniques required to handle complex computer models with potential applications to astronomy. Computer experiments play a critical role in almost all fields of scientific research and engineering. These computer…

Instrumentation and Methods for Astrophysics · Physics 2021-09-01 Joshua Lukemire , Qian Xiao , Abhyuday Mandal , Weng Kee Wong

The stochastic growth-fragmentation model describes the temporal evolution of a structured cell population through a discrete-time and continuous-state Markov chain. The simulations of this stochastic process and its invariant measure are…

Numerical Analysis · Mathematics 2025-05-20 Dawei Wu , Zhennan Zhou

Stochastic models in which agents interact with their neighborhood according to a network topology are a powerful modeling framework to study the emergence of complex dynamic patterns in real-world systems. Stochastic simulations are often…

Social and Information Networks · Computer Science 2021-01-27 Gerrit Großmann , Luca Bortolussi , Verena Wolf

Predictive equivalence in discrete stochastic processes have been applied with great success to identify randomness and structure in statistical physics and chaotic dynamical systems and to inferring hidden Markov models. We examine the…

Statistical Mechanics · Physics 2021-09-21 Samuel P. Loomis , James P. Crutchfield

The initial transient phase of an emerging epidemic is of critical importance for data-driven model building, model-based prediction of the epidemic trend, and articulation of control/prevention strategies. In principle, quantitative models…

Physics and Society · Physics 2023-07-06 Mi Feng , Liang Tian , Ying-Cheng Lai , Changsong Zhou

Sweepstakes reproduction may be generated by chance matching of reproduction with favorable environmental conditions. Gene genealogies generated by sweepstakes reproduction are in the domain of attraction of multiple-merger coalescents…

Probability · Mathematics 2026-01-15 Bjarki Eldon

Piecewise-deterministic Markov processes (PDMPs) offer a powerful stochastic modeling framework that combines deterministic trajectories with random perturbations at random times. Estimating their local characteristics (particularly the…

Methodology · Statistics 2025-12-29 Romain Azaïs , Solune Denis

Many real-world problems encountered in several disciplines deal with the modeling of time-series containing different underlying dynamical regimes, for which probabilistic approaches are very often employed. In this paper we describe…

Machine Learning · Statistics 2015-03-19 Silvia Chiappa

Complex behaviour in many systems arises from the stochastic interactions of spatially distributed particles or agents. Stochastic reaction-diffusion processes are widely used to model such behaviour in disciplines ranging from biology to…

Statistical Mechanics · Physics 2016-08-23 David Schnoerr , Ramon Grima , Guido Sanguinetti

Reciprocal processes are acausal generalizations of Markov processes introduced by Bernstein in 1932. In the literature, a significant amount of attention has been focused on developing dynamical models for reciprocal processes. In this…

Machine Learning · Statistics 2016-05-16 Francesca Paola Carli

We introduce Generator Matching, a modality-agnostic framework for generative modeling using arbitrary Markov processes. Generators characterize the infinitesimal evolution of a Markov process, which we leverage for generative modeling in a…

Machine Learning · Computer Science 2025-02-28 Peter Holderrieth , Marton Havasi , Jason Yim , Neta Shaul , Itai Gat , Tommi Jaakkola , Brian Karrer , Ricky T. Q. Chen , Yaron Lipman

We consider the use of language models whose size and accuracy are intermediate between different order n-gram models. Two types of models are studied in particular. Aggregate Markov models are class-based bigram models in which the mapping…

cmp-lg · Computer Science 2008-02-03 Lawrence Saul , Fernando Pereira

In this proof-of-concept work, we evaluate the performance of multiple machine-learning methods as statistical emulators for use in the analysis of agent-based models (ABMs). Analysing ABM outputs can be challenging, as the relationships…

Multiagent Systems · Computer Science 2021-07-27 Claudio Angione , Eric Silverman , Elisabeth Yaneske

Longitudinal molecular data of rapidly evolving viruses and pathogens provide information about disease spread and complement traditional surveillance approaches based on case count data. The coalescent is used to model the genealogy that…

Applications · Statistics 2020-09-07 Lorenzo Cappello , Julia A. Palacios

Although quantum coherence is a basic trait of quantum mechanics, the presence of coherences in the quantum description of a certain phenomenon does not rule out the possibility to give an alternative description of the same phenomenon in…

Quantum Physics · Physics 2018-12-07 Andrea Smirne , Dario Egloff , María García Díaz , Martin B. Plenio , Susana F. Huelga
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