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Spinal metastasis is the most common disease in bone metastasis and may cause pain, instability and neurological injuries. Early detection of spinal metastasis is critical for accurate staging and optimal treatment. The diagnosis is usually…

Computer Vision and Pattern Recognition · Computer Science 2024-02-15 Shiqi Peng , Bolin Lai , Guangyu Yao , Xiaoyun Zhang , Ya Zhang , Yan-Feng Wang , Hui Zhao

When a neural network estimates someone's age from a photograph, does it process biometric data? The answer depends on whether identity-discriminative representations arise within the network during inference, a question that may seem…

Computers and Society · Computer Science 2026-05-19 Nikita Marshalkin

Objective: A digital twin of a patient can be a valuable tool for enhancing clinical tasks such as workflow automation, patient-specific X-ray dose optimization, markerless tracking, positioning, and navigation assistance in image-guided…

Computer Vision and Pattern Recognition · Computer Science 2023-03-10 Karthik Shetty , Annette Birkhold , Srikrishna Jaganathan , Norbert Strobel , Bernhard Egger , Markus Kowarschik , Andreas Maier

Background: While deep learning technology, which has the capability of obtaining latent representations based on large-scale data, can be a potential solution for the discovery of a novel aging biomarker, existing deep learning methods for…

Machine Learning · Computer Science 2023-02-02 Seong-Eun Moon , Ji Won Yoon , Shinyoung Joo , Yoohyung Kim , Jae Hyun Bae , Seokho Yoon , Haanju Yoo , Young Min Cho

As global life expectancy increases, so does the burden of chronic diseases, yet individuals exhibit considerable variability in the rate at which they age. Identifying biomarkers that distinguish fast from slow ageing is crucial for…

Image and Video Processing · Electrical Eng. & Systems 2024-11-27 Kaustubh Chakradeo , Pernille Nielsen , Lise Mette Rahbek Gjerdrum , Gry Sahl Hansen , David A Duchêne , Laust H Mortensen , Majken K Jensen , Samir Bhatt

The amounts of muscle and fat in a person's body, known as body composition, are correlated with cancer risks, cancer survival, and cardiovascular risk. The current gold standard for measuring body composition requires time-consuming manual…

Epigenetic aging clocks play a pivotal role in estimating an individual's biological age through the examination of DNA methylation patterns at numerous CpG (Cytosine-phosphate-Guanine) sites within their genome. However, making valid…

Machine Learning · Statistics 2026-01-21 Zhe Fei , Yi Li

As the global population continues to age, there is an increasing demand for ways to accurately quantify the biological processes underlying aging. Biological age, unlike chronological age, reflects an individual's physiological state,…

Quantitative Methods · Quantitative Biology 2025-08-29 Jared A Kushner , Mohit Pandey , Sandeep , S Kohli

Surgical treatment of complicated knee fractures is guided by real-time imaging using a mobile C-arm. Immediate and continuous control is achieved via 2D anatomy-specific standard views that correspond to a specific C-arm pose relative to…

Image and Video Processing · Electrical Eng. & Systems 2023-05-29 Lisa Kausch , Sarina Thomas , Holger Kunze , Jan Siad El Barbari , Klaus Maier-Hein

Model averaging combines forecasts obtained from a range of models, and it often produces more accurate forecasts than a forecast from a single model. The crucial part of forecast accuracy improvement in using the model averaging lies in…

Applications · Statistics 2018-10-01 Han Lin Shang , Steven Haberman

Chronological age of healthy people is able to be predicted accurately using deep neural networks from neuroimaging data, and the predicted brain age could serve as a biomarker for detecting aging-related diseases. In this paper, a novel 3D…

Image and Video Processing · Electrical Eng. & Systems 2021-06-08 Jian Cheng , Ziyang Liu , Hao Guan , Zhenzhou Wu , Haogang Zhu , Jiyang Jiang , Wei Wen , Dacheng Tao , Tao Liu

Osteoporosis is a widespread and chronic metabolic bone disease that often remains undiagnosed and untreated due to limited access to bone mineral density (BMD) tests like Dual-energy X-ray absorptiometry (DXA). In response to this…

Image and Video Processing · Electrical Eng. & Systems 2023-11-14 Hyungeun Lee , Ung Hwang , Seungwon Yu , Chang-Hun Lee , Kijung Yoon

Age estimation is an important yet very challenging problem in computer vision. Existing methods for age estimation usually apply a divide-and-conquer strategy to deal with heterogeneous data caused by the non-stationary aging process.…

Computer Vision and Pattern Recognition · Computer Science 2019-04-09 Wanhua Li , Jiwen Lu , Jianjiang Feng , Chunjing Xu , Jie Zhou , Qi Tian

Age estimation is a difficult task which requires the automatic detection and interpretation of facial features. Recently, Convolutional Neural Networks (CNNs) have made remarkable improvement on learning age patterns from benchmark…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-05-23 Zhenzhen Hui , Peng Sun , Yonggang Wen

Manual segmentation of medical images (e.g., segmenting tumors in CT scans) is a high-effort task that can be accelerated with machine learning techniques. However, selecting the right segmentation approach depends on the evaluation…

Computer Vision and Pattern Recognition · Computer Science 2023-02-09 Seyed M. R. Modaresi , Aomar Osmani , Mohammadreza Razzazi , Abdelghani Chibani

Metabolomic data can potentially enable accurate, non-invasive and low-cost prediction of coronary artery disease. Regression-based analytical approaches however might fail to fully account for interactions between metabolites, rely on a…

Changes over time in brain anatomy can provide important insight for treatment design or scientific analyses. We present a method that predicts how a brain MRI for an individual will change over time. We model changes using a diffeomorphic…

Computer Vision and Pattern Recognition · Computer Science 2020-06-02 Marianne Rakic , John Guttag , Adrian V. Dalca

The differential diagnosis of neurodegenerative diseases, characterized by overlapping symptoms, may be challenging. Brain imaging coupled with artificial intelligence has been previously proposed for diagnostic support, but most of these…

Image and Video Processing · Electrical Eng. & Systems 2025-02-21 Pierrick Coupé , Boris Mansencal , José V. Manjón , Patrice Péran , Wassilios G. Meissner , Thomas Tourdias , Vincent Planche

Skin cancer is the most common cancer in the existing world constituting one-third of the cancer cases. Benign skin cancers are not fatal, can be cured with proper medication. But it is not the same as the malignant skin cancers. In the…

Image and Video Processing · Electrical Eng. & Systems 2022-12-21 Dusa Sai Charan , Hemanth Nadipineni , Subin Sahayam , Umarani Jayaraman

Incorporating boundaries of the imaging object as a priori information to imaging algorithms can significantly improve the performance of electromagnetic medical imaging systems. To avoid overly complicating the system by using different…

Computer Vision and Pattern Recognition · Computer Science 2022-03-14 A. Al-Saffar , A. Stancombe , A. Zamani , A. Abbosh