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Wavelength discriminating systems typically consist of heavy benchtop-based instruments, comprising diffractive optics, moving parts, and adjacent detectors. For simple wavelengths measurements, such as lab-on-chip light source calibration…

Longer near-infrared wavelengths provide better penetration depth in biological tissues, so these are useful for plasmonic photothermal cancer therapeutics. In the context of nanoparticles for such applications, the absorption can be tuned…

Optics · Physics 2023-03-21 Dheeraj Pratap , Rizul Gautam , Amit Kumar Shaw , Vikas , Sanjeev Soni

Fourier ptychographic microscopy allows for the collection of images with a high space-bandwidth product at the cost of temporal resolution. In Fourier ptychographic microscopy, the light source of a conventional widefield microscope is…

Image and Video Processing · Electrical Eng. & Systems 2019-01-30 Yi Fei Cheng , Megan Strachan , Zachary Weiss , Moniher Deb , Dawn Carone , Vidya Ganapati

The most realistic information about the transparent sample such as a live cell can be obtained only using bright-field light microscopy. At high-intensity pulsing LED illumination, we captured a primary 12-bit-per-channel (bpc) response…

Image and Video Processing · Electrical Eng. & Systems 2021-08-18 Ganna Platonova , Dalibor Stys , Pavel Soucek , Kirill Lonhus , Jan Valenta , Renata Rychtarikova

Despite the broadband nature of thermal light sources, optical spectroscopy over multiple spectral bands simultaneously remains challenging. Here, we demonstrate a practical Fourier transform infrared spectrometer (FTIR) that achieves…

Interferometric scattering microscopy has been a very promising technology for highly sensitive label-free imaging of a broad spectrum of biological nanoparticles from proteins to viruses in a high-throughput manner. Although it can reveal…

Optics · Physics 2021-08-11 Celalettin Yurdakul , Haonan Zong , Yeran Bai , Ji-Xin Cheng , M. Selim Unlu

This work is concerned with the problem of blind source separation and its applications to imaging. We first establish a theoretical result that we stated in our previous article on imaging in diffusive environments. This result is a…

Numerical Analysis · Mathematics 2026-02-12 Randy Bartels , Olivier Pinaud

We propose a novel framework to automatically learn to aggregate and transform photometric measurements from multiple unstructured views into spatially distinctive and view-invariant low-level features, which are subsequently fed to a…

Computer Vision and Pattern Recognition · Computer Science 2024-12-12 Xiang Feng , Kaizhang Kang , Fan Pei , Huakeng Ding , Jinjiang You , Ping Tan , Kun Zhou , Hongzhi Wu

Fourier transform spectroscopy based on incoherent light sources is a well-established tool in research fields from molecular spectroscopy and atmospheric monitoring to material science and biophysics. It provides broadband molecular…

We demonstrate a chip-integrated emission spectroscope capable of retrieving the temperature of the light sources. It consists of a single photon detector with low dark counts and a sweeping on-chip filter with 2 pm spectral resolution in…

In this article, we propose a new BSS approach for identifying skin diseases from RGB images that proceeds in two steps. We begin by separating the three main chromophores (oxyhemoglobin, deoxyhemoglobin and melanin) using Non-negative…

Medical Physics · Physics 2023-10-03 Mustapha Zokay , Hicham Saylani

Intra-operative measurements of tissue shape and multi/ hyperspectral information have the potential to provide surgical guidance and decision making support. We report an optical probe based system to combine sparse hyperspectral…

Computer Vision and Pattern Recognition · Computer Science 2017-06-22 Jianyu Lin , Neil T. Clancy , Yang Hu , Ji Qi , Taran Tatla , Danail Stoyanov , Lena Maier-Hein , Daniel S. Elson

Phase-contrast microscopy converts the optical phase introduced by transparent, unlabeled specimens into modulation in the intensity image. Modern phase imaging techniques are capable of quantifying phase shift at each point in the field of…

FOS, which means light in Greek, is an open-source program for Fast Optical Spectrum calculations of nanoparticle media. This program takes the material properties and a description of the system as input, and outputs the spectral response…

Computational Physics · Physics 2024-09-04 Daniel Carne , Joseph Peoples , Ziqi Guo , Dudong Feng , Zherui Han , Xiaojie Liu , Xiulin Ruan

Hyperspectral cameras face harsh trade-offs between spatial, spectral, and temporal resolution in inherently low-photon conditions. Computational imaging systems break through these trade-offs with compressive sensing, but have required…

Computer Vision and Pattern Recognition · Computer Science 2026-02-12 M. Kerem Aydin , Yi-Chun Hung , Jaclyn Pytlarz , Qi Guo , Emma Alexander

Fourier Ptychographic Microscopy (FPM) is a computational imaging method that is able to super-resolve features beyond the diffraction-limit set by the objective lens of a traditional microscope. This is accomplished by using synthetic…

Signal Processing · Electrical Eng. & Systems 2019-04-09 Michael Kellman , Emrah Bostan , Michael Chen , Laura Waller

Versatile, ultracompact, easy-to-handle, high-sensitivity sensors are compelling tools for in situ pivotal applications, such as medical diagnostics, security and safety assessments, and environmental control. In this work, we combine…

Phosphorene, a single atomic layer of black phosphorus, has recently emerged as a new twodimensional (2D) material that holds promise for electronic and photonic technology. Here we experimentally demonstrate that the electronic structure…

The art of imparting information onto a light wave by optical signal modulation is fundamental to all forms of optical communication. Among many schemes, direct modulation of laser diodes stands out as a simple, robust, and cost effective…

Quantum Physics · Physics 2016-09-28 Z. L. Yuan , B. Fr\"ohlich , M. Lucamarini , G. L. Roberts , J. F. Dynes , A. J. Shields

The thin and flexible nature of optical fibres often makes them the ideal technology to view biological processes in-vivo, but current microendoscopic approaches are limited in spatial resolution. Here, we demonstrate a new route to high…