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Phylogenetic analyses of gene expression have great potential for addressing a wide range of questions. These analyses will, for example, identify genes that have evolutionary shifts in expression that are correlated with evolutionary…

Populations and Evolution · Quantitative Biology 2014-01-14 Casey W. Dunn , Xi Luo , Zhijin Wu

Set covering problem is an important class of combinatorial optimization problems, which has been widely applied and studied in many fields. In this paper, we propose an improved column generation algorithm with neural prediction (CG-P) for…

Machine Learning · Computer Science 2022-07-13 Haofeng Yuan , Peng Jiang , Shiji Song

The Consecutive-Ones Property (C1P) is a classical concept in discrete mathematics that has been used in several genomics applications, from physical mapping of contemporary genomes to the assembly of ancient genomes. A common issue in…

Data Structures and Algorithms · Computer Science 2013-06-21 Cedric Chauve , Murray Patterson , Ashok Rajaraman

We study the problem of maximizing a monotone submodular function with viability constraints. This problem originates from computational biology, where we are given a phylogenetic tree over a set of species and a directed graph, the…

Data Structures and Algorithms · Computer Science 2016-11-18 Wolfgang Dvořák , Monika Henzinger , David P. Williamson

Recent advances in text-to-image generation models have unlocked vast potential for visual creativity. However, the users that use these models struggle with the generation of consistent characters, a crucial aspect for numerous real-world…

Computer Vision and Pattern Recognition · Computer Science 2024-07-16 Omri Avrahami , Amir Hertz , Yael Vinker , Moab Arar , Shlomi Fruchter , Ohad Fried , Daniel Cohen-Or , Dani Lischinski

Linear Genetic Programming (LGP) is a powerful technique that allows for a variety of problems to be solved using a linear representation of programs. However, there still exists some limitations to the technique, such as the need for…

Neural and Evolutionary Computing · Computer Science 2026-01-16 Urmzd Mukhammadnaim

We introduce a problem class we call Polynomial Constraint Satisfaction Problems, or PCSP. Where the usual CSPs from computer science and optimization have real-valued score functions, and partition functions from physics have monomials,…

Discrete Mathematics · Computer Science 2010-01-14 Alexander D. Scott , Gregory B. Sorkin

Traditional Linear Genetic Programming (LGP) algorithms are based only on the selection mechanism to guide the search. Genetic operators combine or mutate random portions of the individuals, without knowing if the result will lead to a…

Neural and Evolutionary Computing · Computer Science 2017-04-05 Léo Françoso Dal Piccol Sotto , Vinícius Veloso de Melo

Contemporary genetic programming (GP) systems for general program synthesis have been primarily concerned with evolving programs that can manipulate values from a standard set of primitive data types and simple indexed data structures. In…

Neural and Evolutionary Computing · Computer Science 2023-06-09 Edward Pantridge , Thomas Helmuth

Here we show that deciding whether two rooted binary phylogenetic trees on the same set of taxa permit a cherry-picking sequence, a special type of elimination order on the taxa, is NP-complete. This improves on an earlier result which…

Populations and Evolution · Quantitative Biology 2021-04-13 Janosch Döcker , Leo van Iersel , Steven Kelk , Simone Linz

A decision problem is called parameterized if its input is a pair of strings. One of these strings is referred to as a parameter. The problem: given a propositional logic program P and a non-negative integer k, decide whether P has a stable…

Logic in Computer Science · Computer Science 2007-05-23 Zbigniew Lonc , Miroslaw Truszczynski

Given an indeterminate string pattern $p$ and an indeterminate string text $t$, the problem of order-preserving pattern matching with character uncertainties ($\mu$OPPM) is to find all substrings of $t$ that satisfy one of the possible…

Data Structures and Algorithms · Computer Science 2019-05-08 Diogo Costa , Luís M. S. Russo , Rui Henriques , Hideo Bannai , Alexandre P. Francisco

This work aims to introduce the framework of polynomial optimization theory to solve fractional polynomial problems (FPPs). Unlike other widely used optimization frameworks, the proposed one applies to a larger class of FPPs, not…

Information Theory · Computer Science 2018-10-17 Andrea Pizzo , Alessio Zappone , Luca Sanguinetti

In phylogenetic analysis, for non-molecular data, particularly morphology, parsimony optimization is the most commonly employed approach. In the past and present application of the parsimony principle, extra step numbers have been added…

Populations and Evolution · Quantitative Biology 2016-10-12 Yue Zhang

We investigate the parameterized complexity of finding subgraphs with hereditary properties on graphs belonging to a hereditary graph class. Given a graph $G$, a non-trivial hereditary property $\Pi$ and an integer parameter $k$, the…

Data Structures and Algorithms · Computer Science 2021-01-26 David Eppstein , Siddharth Gupta , Elham Havvaei

We study distributed algorithms for string matching problem in presence of wildcard characters. Given a string T (a text), we look for all occurrences of another string P (a pattern) as a substring of string T . Each wildcard character in…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-06-08 MohammadTaghi Hajiaghayi , Hamed Saleh , Saeed Seddighin , Xiaorui Sun

The closest pair problem (CPP) is one of the well studied and fundamental problems in computing. Given a set of points in a metric space, the problem is to identify the pair of closest points. Another closely related problem is the fixed…

Data Structures and Algorithms · Computer Science 2014-07-22 Sanguthevar Rajasekaran , Sudipta Pathak

Perfect Matching-Cut is the problem of deciding whether a graph has a perfect matching that contains an edge-cut. We show that this problem is NP-complete for planar graphs with maximum degree four, for planar graphs with girth five, for…

Combinatorics · Mathematics 2021-11-01 Valentin Bouquet , Christophe Picouleau

We study the graphs formed from instances of the stable matching problem by connecting pairs of elements with an edge when there exists a stable matching in which they are matched. Our results include the NP-completeness of recognizing…

Discrete Mathematics · Computer Science 2020-10-20 David Eppstein

Phylogenetic trees are simple models of evolutionary processes. They describe conditionally independent divergent evolution of taxa from common ancestors. Phylogenetic trees commonly do not have enough flexibility to adequately model all…

Populations and Evolution · Quantitative Biology 2025-11-11 Jonathan D. Mitchell , Barbara R. Holland
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