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We analyze the psychophysical responses of human observers to an ensemble of monomolecular odorants. Each odorant is characterized by a set of 146 perceptual descriptors obtained from a database of odor character profiles. Each odorant is…

Neurons and Cognition · Quantitative Biology 2009-07-24 Alexei A. Koulakov , Armen G. Enikolopov , Dmitry Rinberg

The insect olfactory system, which includes the antennal lobe (AL), mushroom body (MB), and ancillary structures, is a relatively simple neural system capable of learning. Its structural features, which are widespread in biological neural…

Neurons and Cognition · Quantitative Biology 2018-02-09 Charles B. Delahunt , Jeffrey A. Riffell , J. Nathan Kutz

We present a novel machine learning architecture for classification suggested by experiments on olfactory systems. The network separates input stimuli, represented as spatially distinct currents, via winnerless competition---a process based…

Biological Physics · Physics 2020-06-18 Jason A. Platt , Anna Miller , Lawson Fuller , Henry D. I. Abarbanel

Olfaction -- how molecules are perceived as odors to humans -- remains poorly understood. Recently, the principal odor map (POM) was introduced to digitize the olfactory properties of single compounds. However, smells in real life are not…

Machine Learning · Computer Science 2025-01-28 Gary Tom , Cher Tian Ser , Ella M. Rajaonson , Stanley Lo , Hyun Suk Park , Brian K. Lee , Benjamin Sanchez-Lengeling

Olfactory receptor usage is highly heterogeneous, with some receptor types being orders of magnitude more abundant than others. We propose an explanation for this striking fact: the receptor distribution is tuned to maximally represent…

Neurons and Cognition · Quantitative Biology 2019-01-23 Tiberiu Tesileanu , Simona Cocco , Remi Monasson , Vijay Balasubramanian

Neuromorphic computing is one of the few current approaches that have the potential to significantly reduce power consumption in Machine Learning and Artificial Intelligence. Imam & Cleland presented an odour-learning algorithm that runs on…

Neural and Evolutionary Computing · Computer Science 2023-09-22 Nik Dennler , André van Schaik , Michael Schmuker

This research introduces a Machine Learning-centric approach to replicate olfactory experiences, validated through experimental quantification of perfume perception. Key contributions encompass a hybrid model connecting perfume molecular…

Finding an odor source in a turbulent flow requires effectively leveraging the history of olfactory observations into a robust navigation strategy. In this work, we use tabular Q-learning to train an olfactory search agent with a minimal…

Biological Physics · Physics 2026-05-18 Marco Rando , Robin A. Heinonen , Yujia Qi , Agnese Seminara

Olfactory systems use a small number of broadly sensitive receptors to combinatorially encode a vast number of odors. We propose a method of decoding such distributed representations by exploiting a statistical fact: receptors that do not…

Neurons and Cognition · Quantitative Biology 2021-09-01 Vijay Singh , Martin Tchernookov , Vijay Balasubramanian

Molecular communication (MC) has promising potential and a wide range of applications. However, odor-based communication which is common in nature, has not been sufficiently examined within the context of MC, yet. In this paper, we…

Emerging Technologies · Computer Science 2024-11-01 Fatih E. Bilgen , Ahmet B. Kilic , Ozgur B. Akan

Locating the source of odor in a turbulent environment - a common behavior for living organisms - is non-trivial because of the random nature of mixing. Here we analyze the statistical physics aspects of the problem and propose an efficient…

Chaotic Dynamics · Physics 2009-11-07 Eugene Balkovsky , Boris I. Shraiman

Navigation by scent is a capability in robotic systems that is rising in demand. However, current methods often suffer from ambiguities, particularly when robots misattribute odours to incorrect objects due to limitations in olfactory…

Robotics · Computer Science 2025-09-23 Kordel K. France , Ovidiu Daescu

Olfaction, the sense of smell, has received scant attention from a signal processing perspective in comparison to audition and vision. In this paper, we develop a signal processing paradigm for olfactory signals based on new scientific…

Information Theory · Computer Science 2015-09-16 Kush R. Varshney , Lav R. Varshney

Fruit flies are established model systems for studying olfactory learning as they will readily learn to associate odors with both electric shock or sugar rewards. The mechanisms of the insect brain apparently responsible for odor learning…

Machine Learning · Computer Science 2025-01-09 Jinyung Hong , Theodore P. Pavlic

Molecular communication is a new, active area of research that has created a paradigm shift in the way a communication system is perceived. An artificial molecular communication network is created using biological molecules for encoding,…

Emerging Technologies · Computer Science 2023-12-01 Aditya Powari , Ozgur B. Akan

Animals have evolved to rapidly detect and recognise brief and intermittent encounters with odour packages, exhibiting recognition capabilities within milliseconds. Artificial olfaction has faced challenges in achieving comparable results…

Tracking a turbulent plume to locate its source is a complex control problem because it requires multi-sensory integration and must be robust to intermittent odors, changing wind direction, and variable plume statistics. This task is…

Neurons and Cognition · Quantitative Biology 2021-12-21 Satpreet Harcharan Singh , Floris van Breugel , Rajesh P. N. Rao , Bingni Wen Brunton

Given the structure of a novel molecule, there is still no one who can reliably predict what odor percept that molecule will evoke. The challenge comes from both the difficulty in quantitatively characterizing molecular structure, and the…

Neurons and Cognition · Quantitative Biology 2018-06-08 Daniel Kepple , Alexei Koulakov

We use the power density spectra obtained by fluctuation-enhanced sensing of bacterial odors (Escherichia coli and Anthrax-surrogate Bacillus subtilis) to generate new, highly distinguishable, types of patterns based on the average slope of…

General Physics · Physics 2012-02-20 Hung-Chih Chang , Laszlo B. Kish , Maria D. King , Chiman Kwan

The standard model for molecular recognition of an odorant is that receptor sites discriminate by molecular geometry as evidenced that two chiral molecules may smell very differently. However, recent studies of isotopically labeled…

Biological Physics · Physics 2015-06-05 Eric R. Bittner , Adrian Madalan , Arkadiuz Czader , Gregg Roman