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Genomic data are becoming increasingly valuable as we develop methods to utilize the information at scale and gain a greater understanding of how genetic information relates to biological function. Advances in synthetic biology and the…

The problem we address is the following: how can a user employ a predictive model that is held by a third party, without compromising private information. For example, a hospital may wish to use a cloud service to predict the readmission…

Machine Learning · Computer Science 2014-12-25 Pengtao Xie , Misha Bilenko , Tom Finley , Ran Gilad-Bachrach , Kristin Lauter , Michael Naehrig

Quantum neural networks (QNNs) are gaining increasing interest due to their potential to detect complex patterns in data by leveraging uniquely quantum phenomena. This makes them particularly promising for biomedical applications. In these…

Quantum Physics · Physics 2025-09-17 Gaoyuan Wang , Jonathan Warrell , Mark Gerstein

DNA has emerged as a promising alternative for long-term data storage due to its high capacity, durability, and low-energy potential. However, storing data in DNA presents several challenges. First, it requires complex and costly…

Other Quantitative Biology · Quantitative Biology 2025-11-20 Sara Al Sayyed , Aline Roumy , Thomas Maugey

Significant volumes of knowledge have been accumulated in recent years linking subtle genetic variations to a wide variety of medical disorders from Cystic Fibrosis to mental retardation. Nevertheless, there are still great challenges in…

Genomics · Quantitative Biology 2016-11-17 Yaniv Erlich , Assaf Gordon , Michael Brand , Gregory J. Hannon , Partha P. Mitra

In this paper, we study methods for improving the efficiency and privacy of compressed DNA sequence comparison computations, under various querying scenarios. For instance, one scenario involves a querier, Bob, who wants to test if his DNA…

Cryptography and Security · Computer Science 2011-07-20 David Eppstein , Michael T. Goodrich , Pierre Baldi

Camouflaged object detection (COD) aims to accurately detect objects hidden in the surrounding environment. However, the existing COD methods mainly locate camouflaged objects in the RGB domain, their performance has not been fully…

Computer Vision and Pattern Recognition · Computer Science 2024-12-10 Runmin Cong , Mengyao Sun , Sanyi Zhang , Xiaofei Zhou , Wei Zhang , Yao Zhao

Suppose Alice holds a DNA sequence and Bob owns a database of DNA sequences. They want to determine whether there is a match for the Alice's input in the Bob's database for any purpose such as diagnosis of Alice's disease. However, Alice…

Cryptography and Security · Computer Science 2018-09-25 Parisa Kaghazgaran

Understanding functional organization of genetic information is a major challenge in modern biology. Following the initial publication of the human genome sequence in 2001, advances in high-throughput measurement technologies and efficient…

Machine Learning · Statistics 2011-03-01 Leo Lahti

As a possible implementation of data storage using DNA, multiple strands of DNA are stored in a liquid container so that, in the future, they can be read by an array of DNA readers in parallel. These readers will sample the strands with…

Information Theory · Computer Science 2024-09-04 Hsin-Po Wang , Venkatesan Guruswami

Federated learning has been proposed as a privacy-preserving machine learning framework that enables multiple clients to collaborate without sharing raw data. However, client privacy protection is not guaranteed by design in this framework.…

Cryptography and Security · Computer Science 2022-10-17 Kai Yue , Richeng Jin , Chau-Wai Wong , Dror Baron , Huaiyu Dai

In this Letter, we propose a new approach to process high-dimensional quantum information encoded in a photon frequency domain. In contrast to previous approaches based on nonlinear optical processes, no active control of photon energy is…

Quantum Physics · Physics 2020-07-16 Chaohan Cui , Kaushik P. Seshadreesan , Saikat Guha , Linran Fan

Data is used widely by service providers as input to inference systems to perform decision making for authorized tasks. The raw data however allows a service provider to infer other sensitive information it has not been authorized for. We…

Cryptography and Security · Computer Science 2020-10-26 Chong Xiao Wang , Wee Peng Tay

Face recognition technology has been deployed in various real-life applications. The most sophisticated deep learning-based face recognition systems rely on training millions of face images through complex deep neural networks to achieve…

Computer Vision and Pattern Recognition · Computer Science 2024-01-25 Dong Han , Yong Li , Joachim Denzler

Future quantum computers are likely to be expensive and affordable outright by few, motivating client/server models for outsourced computation. However, the applications for quantum computing will often involve sensitive data, and the…

Quantum Physics · Physics 2020-03-25 Yingkai Ouyang , Si-Hui Tan , Joseph Fitzsimons , Peter P. Rohde

Technology progress in DNA sequencing boosts the genomic database growth at faster and faster rate. Compression, accompanied with random access capabilities, is the key to maintain those huge amounts of data. In this paper we present an…

Computational Engineering, Finance, and Science · Computer Science 2011-03-14 Szymon Grabowski , Sebastian Deorowicz

High-throughput shotgun sequence data makes it possible in principle to accurately estimate population genetic parameters without confounding by SNP ascertainment bias. One such statistic of interest is the proportion of heterozygous sites…

Populations and Evolution · Quantitative Biology 2012-12-18 Katarzyna Bryc , Nick Patterson , David Reich

Relative compression, where a set of similar strings are compressed with respect to a reference string, is a very effective method of compressing DNA datasets containing multiple similar sequences. Relative compression is fast to perform…

Quantitative Methods · Quantitative Biology 2011-06-21 Shanika Kuruppu , Simon Puglisi , Justin Zobel

Data mining deals with automatic extraction of previously unknown patterns from large amounts of data. Organizations all over the world handle large amounts of data and are dependent on mining gigantic data sets for expansion of their…

Cryptography and Security · Computer Science 2010-03-25 Mohammad Ali Kadampur , Somayajulu D. V. L. N

Identifying subgroups and properties of cancer biopsy samples is a crucial step towards obtaining precise diagnoses and being able to perform personalized treatment of cancer patients. Recent data collections provide a comprehensive…

Genomics · Quantitative Biology 2021-04-23 Stefan Groha , Caroline Weis , Alexander Gusev , Bastian Rieck
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