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Respondent-Driven Sampling is a method to sample hard-to-reach human populations by link-tracing over their social networks. Beginning with a convenience sample, each person sampled is given a small number of uniquely identified coupons to…

Methodology · Statistics 2011-08-02 Krista J. Gile , Mark S. Handcock

DNA evidence use in problems of civil and criminal identification is becoming greater. The necessity of evaluating the weight of that evidence may be accomplished using one of the most known powerful tools: the Bayesian networks. In the…

Physics and Society · Physics 2025-12-01 Marina Andrade , Manuel Alberto M. Ferreira

The role of direct cell-to-cell spread in viral infections - where virions spread between host and susceptible cells without needing to be secreted into the extracellular environment - has come to be understood as essential to the dynamics…

Quantitative Methods · Quantitative Biology 2024-05-21 Thomas Williams , James M. McCaw , James Osborne

The notion of hypothetical bias (HB) constitutes, arguably, the most fundamental issue in relation to the use of hypothetical survey methods. Whether or to what extent choices of survey participants and subsequent inferred estimates…

Econometrics · Economics 2021-09-08 Milad Haghani , Michiel C. J. Bliemer , John M. Rose , Harmen Oppewal , Emily Lancsar

One way in which the human immunodeficiency virus (HIV-1) replicates within a host is by infecting activated CD4+ T-cells, which then produce additional copies of the virus. Even with the introduction of antiretroviral drug therapy, which…

Dynamical Systems · Mathematics 2016-04-18 Stephen Pankavich

Human immunodeficiency virus (HIV-1 or simply HIV) induces a persistent infection, which in the absence of treatment leads to AIDS and death in almost all infected individuals. HIV infection elicits a vigorous immune response starting about…

Populations and Evolution · Quantitative Biology 2015-06-05 Vitaly V. Ganusov , Richard A. Neher , Alan S. Perelson

The development of a new diagnostic test ideally follows a sequence of stages which, amongst other aims, evaluate technical performance. This includes an analytical validity study, a diagnostic accuracy study and an interventional clinical…

Introduction: The value of integrating federal HIV services data with HIV surveillance is currently unknown. Upstream and complete case capture is essential in preventing future HIV transmission. Methods: This study integrated Ryan White,…

Machine Learning · Computer Science 2023-04-21 Nick Williams

Meta-analysis is a statistical method used in evidence synthesis for combining, analyzing and summarizing studies that have the same target endpoint and aims to derive a pooled quantitative estimate using fixed and random effects models or…

Methodology · Statistics 2022-04-25 Ivette Raices Cruz , Matthias C. M. Troffaes , Johan Lindström , Ullrika Sahlin

Epidemic models are invaluable tools to understand and implement strategies to control the spread of infectious diseases, as well as to inform public health policies and resource allocation. However, current modeling approaches have…

Methodology · Statistics 2026-05-12 Caitlin Ward , Rob Deardon , Alexandra M. Schmidt

How to estimate heterogeneity, e.g. the effect of some variable differing across observations, is a key question in political science. Methods for doing so make simplifying assumptions about the underlying nature of the heterogeneity to…

Methodology · Statistics 2021-03-31 Max Goplerud

Many resources for forensic scholars and practitioners, such as journal articles, guidance documents, and textbooks, address how to make a value of evidence assessment in the form of a likelihood ratio (LR) when deciding between two…

Applications · Statistics 2022-05-11 Steven Lund , Hari Iyer

Exposure measurement error is a ubiquitous but often overlooked challenge in causal inference with observational data. Existing methods accounting for exposure measurement error largely rely on restrictive parametric assumptions, while…

The spread of COVID-19 makes it essential to investigate its prevalence. In such investigation research, as far as we know, the widely-used sampling methods didn't use the information sufficiently about the numbers of the previously…

Applications · Statistics 2022-01-04 Ze Liu , Siyu Yi , Jianghu , Dong , Min-Qian Liu , Yongdao Zhou

Unlike classification, whose goal is to estimate the class of each data point in a dataset, prevalence estimation or quantification is a task that aims to estimate the distribution of classes in a dataset. The two main tasks in prevalence…

Machine Learning · Statistics 2025-07-09 Aime Bienfait Igiraneza , Christophe Fraser , Robert Hinch

Background: Bayesian Networks (BNs) are probabilistic graphical models that leverage Bayes' theorem to portray dependencies and cause-and-effect relationships between variables. These networks have gained prominence in the field of health…

This paper proposes a Bayesian method for estimating the parameters of a normal distribution when only limited summary statistics (sample mean, minimum, maximum, and sample size) are available. To estimate the parameters of a normal…

Methodology · Statistics 2024-11-21 Tomoki Matsumoto

Infectious diseases are studied to understand their spreading mechanisms, to evaluate control strategies and to predict the risk and course of future outbreaks. Because people only interact with a small number of individuals, and because…

Applications · Statistics 2018-09-05 Ritabrata Dutta , Antonietta Mira , Jukka-Pekka Onnela

Several diseases related to cell proliferation are characterized by the accumulation of somatic DNA changes, with respect to wildtype conditions. Cancer and HIV are two common examples of such diseases, where the mutational load in the…

Artificial Intelligence · Computer Science 2018-07-06 Daniele Ramazzotti , Alex Graudenzi , Giulio Caravagna , Marco Antoniotti

Although the interest in the the use of social and information networks has grown, most inferences on networks assume the data collected represents the complete. However, when ignoring missing data, even when missing completely at random,…

Methodology · Statistics 2022-03-25 Tyler Vu , Tuo Lin , Jingjing Zou , Vladimir Novitsky , Xin Tu , Victor De Gruttola