English
Related papers

Related papers: Estimation of HIV Burden through Bayesian Evidence…

200 papers

We establish a stochastic HIV/AIDS model for the individuals with protection awareness and reveal how the protection awareness plays its important role in the control of AIDS. We firstly show that there exists a global positive solution for…

Dynamical Systems · Mathematics 2023-03-01 Xuanpei Zhai , Wenshuang Li , Fengying Wei , Xuerong Mao

Familiar statistical tests and estimates are obtained by the direct observation of cases of interest: a clinical trial of a new drug, for instance, will compare the drug's effects on a relevant set of patients and controls. Sometimes,…

Methodology · Statistics 2010-12-09 Bradley Efron

Due to increased awareness of data protection and corresponding laws many data, especially involving sensitive personal information, are not publicly accessible. Accordingly, many data collecting agencies only release aggregated data, e.g.…

Methodology · Statistics 2022-04-12 Rajbir-Singh Nirwan , Nils Bertschinger

When statistical analyses consider multiple data sources, Markov melding provides a method for combining the source-specific Bayesian models. Markov melding joins together submodels that have a common quantity. One challenge is that the…

Methodology · Statistics 2022-03-17 Andrew A. Manderson , Robert J. B. Goudie

In stopping the spread of infectious diseases, pathogen genomic data can be used to reconstruct transmission events and characterize population-level sources of infection. Most approaches for identifying transmission pairs do not account…

In the last months, due to the emergency of Covid-19, questions related to the fact of belonging or not to a particular class of individuals (`infected or not infected'), after being tagged as `positive' or `negative' by a test, have never…

Populations and Evolution · Quantitative Biology 2020-11-23 Giulio D'Agostini , Alfredo Esposito

Bayesian analysis plays a crucial role in estimating distribution of unknown parameters for given data and model. Due to the curse of dimensionality, it becomes difficult for high-dimensional problems, especially when multiple modes exist.…

Methodology · Statistics 2025-07-18 Zihan Liao , Binbin Li , Hua-Ping Wan

This paper explores Bayesian estimation for categorical data, focusing on simple yet effective models that provide a foundation for applying more advanced methods accurately and reliably in real-world applications. We begin by revisiting…

Methodology · Statistics 2025-09-03 Jan Kalina

Sample overlap is a common issue in evidence synthesis in the field of medical research, particularly when integrating findings from observational studies utilizing existing databases such as registries. Due to the general inaccessibility…

Methodology · Statistics 2026-02-26 Zhentian Zhang , Tim Friede , Tim Mathes

A method for implicit variable selection in mixture of experts frameworks is proposed. We introduce a prior structure where information is taken from a set of independent covariates. Robust class membership predictors are identified using a…

Econometrics · Economics 2019-01-15 Gregor Zens

Following [Diggle 2011, Greenland 1995], we give a simple formula for the Bayesian posterior density of a prevalence parameter based on unreliable testing of a population. This problem is of particular importance when the false positive…

Applications · Statistics 2020-09-14 Jonathan Baxter

Psychiatric and social epidemiology often involves assessing the effects of environmental exposure on outcomes that are difficult to measure directly. To address this problem, it is common to measure outcomes using a comprehensive battery…

Households represent a key unit of interest in infectious disease epidemiology, in both empirical studies and mathematical modelling. The within-household transmission potential of a disease is often summarised by a secondary attack ratio…

Applications · Statistics 2026-03-27 Joseph Brooks , Thomas House , Lorenzo Pellis , Joe Hilton

In recent years, empirical Bayesian (EB) inference has become an attractive approach for estimation in parametric models arising in a variety of real-life problems, especially in complex and high-dimensional scientific applications.…

Methodology · Statistics 2023-03-01 Hien D Nguyen , Mayetri Gupta

Modeling viral dynamics in HIV/AIDS studies has resulted in a deep understanding of pathogenesis of HIV infection from which novel antiviral treatment guidance and strategies have been derived. Viral dynamics models based on nonlinear…

Applications · Statistics 2010-10-08 Hua Liang , Hongyu Miao , Hulin Wu

Hypothesis testing and model choice are quintessential questions for statistical inference and while the Bayesian paradigm seems ideally suited for answering these questions, it faces difficulties of its own ranging from prior modelling to…

Methodology · Statistics 2022-06-15 Christian P Robert

During primary HIV infection, the kinetics of plasma virus concentrations and CD4+ cell counts is very complex. Parametric and nonparametric models have been suggested for fitting repeated measurements of these markers. Alternatively,…

Applications · Statistics 2011-01-07 J. Drylewicz , J. Guedj , D. Commenges , R. Thiébaut

We consider a time-delayed HIV/AIDS epidemic model with education dissemination and study the asymptotic dynamics of solutions as well as the asymptotic behavior of the endemic equilibrium with respect to the amount of information…

Dynamical Systems · Mathematics 2021-08-10 Dawit Denu , Sedar Ngoma , Rachidi B. Salako

Meta-analyses of diagnostic test accuracy (DTA) studies have been gaining prominence in research in clinical epidemiology and health technology development. In these DTA meta-analyses, some studies may have markedly different…

Methodology · Statistics 2021-07-14 Yuki Matsushima , Hisashi Noma , Tomohide Yamada , Toshi A. Furukawa

This article introduces novel methodologies for estimating contextual exposure to HIV population viral load using GPS data. We propose a comprehensive analytical framework comprising (i) local (grid-cell level) estimation of HIV population…