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Some scientific publications are under suspicion of fabrication of data. Since humans are bad random number generators, there might be some evidential value in favor of fabrication in the statistical results as presented in such papers. In…

Methodology · Statistics 2013-04-29 Chris A. J. Klaassen

Klaassen in (Klaassen 2015) proposed a method for the detection of data manipulation given the means and standard deviations for the cells of a oneway ANOVA design. This comment critically reviews this method. In addition, inspired by this…

Methodology · Statistics 2015-07-16 Hannes Matuschek

Statistical hypothesis testing, as formalized by 20th Century statisticians and taught in college statistics courses, has been a cornerstone of 100 years of scientific progress. Nevertheless, the methodology is increasingly questioned in…

Methodology · Statistics 2024-08-22 Brian Dennis , Mark L Taper , José M Ponciano

Modern science increasingly relies on ever-growing observational datasets and automated inference pipelines, under the implicit belief that accumulating more data makes scientific conclusions more reliable. Here we show that this belief can…

Machine Learning · Computer Science 2026-02-06 Zhipeng Zhang , Kai Li

Recent advances in generative models facilitate the creation of synthetic data to be made available for research in privacy-sensitive contexts. However, the analysis of synthetic data raises a unique set of methodological challenges. In…

Factorial designs are frequently used in different fields of science, e.g. psychological, medical or biometric studies. Standard approaches, as the ANOVA $F$-test, make different assumptions on the distribution of the error terms, the…

Methodology · Statistics 2018-02-21 Maria Umlauft

For obtaining causal inferences that are objective, and therefore have the best chance of revealing scientific truths, carefully designed and executed randomized experiments are generally considered to be the gold standard. Observational…

Applications · Statistics 2008-11-12 Donald B. Rubin

Functional ANOVA offers a principled framework for interpretability by decomposing a model's prediction into main effects and higher-order interactions. For independent features, this decomposition is well-defined, strongly linked with SHAP…

Machine Learning · Statistics 2026-03-04 Baptiste Ferrere , Nicolas Bousquet , Fabrice Gamboa , Jean-Michel Loubes , Joseph Muré

Analysis of variance (ANOVA) is an extremely important method in exploratory and confirmatory data analysis. Unfortunately, in complex problems (e.g., split-plot designs), it is not always easy to set up an appropriate ANOVA. We propose a…

Statistics Theory · Mathematics 2007-06-13 Andrew Gelman

Instrumental variables have been widely used to estimate the causal effect of a treatment on an outcome. Existing confidence intervals for causal effects based on instrumental variables assume that all of the putative instrumental variables…

Methodology · Statistics 2016-07-14 Hyunseung Kang , T. Tony Cai , Dylan S. Small

Recent studies have shown that many results published in peer-reviewed scientific journals are not reproducible. This raises the following question: why is it so easy to fool myself into believing that a result is reliable when in fact it…

Data Analysis, Statistics and Probability · Physics 2017-06-26 Ole Peters , Maximilian Werner

In this paper, we introduce a novel method to generate interpretable regression function estimators. The idea is based on called data-dependent coverings. The aim is to extract from the data a covering of the feature space instead of a…

Statistics Theory · Mathematics 2021-01-27 Vincent Margot , Jean-Patrick Baudry , Frédéric Guilloux , Olivier Wintenberger

One can argue that one of the main roles of the subject of statistics is to characterize what the evidence in collected data says about questions of scientific interest. There are two broad questions that we will refer to as the estimation…

Statistics Theory · Mathematics 2024-06-11 Michael Evans

Scientific fraud is an increasingly vexing problem. Many current programs for fraud detection focus on image manipulation, while techniques for detection based on anomalous patterns that may be discoverable in the underlying numerical data…

Quantitative Methods · Quantitative Biology 2013-11-22 Joel H Pitt , Helene Z Hill

As artificial intelligence and machine learning tools become more accessible, and scientists face new obstacles to data collection (e.g., rising costs, declining survey response rates), researchers increasingly use predictions from…

Machine Learning · Statistics 2025-12-08 Stephen Salerno , Kentaro Hoffman , Awan Afiaz , Anna Neufeld , Tyler H. McCormick , Jeffrey T. Leek

Although living organisms are affected by many interrelated and unidentified variables, this complexity does not automatically impose a fundamental limitation on statistical inference. Nor need one invoke such complexity as an explanation…

Data Analysis, Statistics and Probability · Physics 2013-02-06 Drew M. Thomas

As artificial intelligence and machine learning tools become more accessible, and scientists face new obstacles to data collection (e.g. rising costs, declining survey response rates), researchers increasingly use predictions from…

Methodology · Statistics 2024-02-06 Kentaro Hoffman , Stephen Salerno , Awan Afiaz , Jeffrey T. Leek , Tyler H. McCormick

This paper makes the case for using Shapley value to quantify the importance of random input variables to a function. Alternatives based on the ANOVA decomposition can run into conceptual and computational problems when the input variables…

Statistics Theory · Mathematics 2017-03-22 Art B. Owen , Clémentine Prieur

Data analyses are often constructed in an imperative manner, where commands representing actions taken on the data are issued sequentially. The publication of these commands, along with the data, is essential to the reproducibility of the…

Other Statistics · Statistics 2026-03-12 Roger D. Peng

Researchers now routinely use AI or other machine learning methods to estimate latent variables of economic interest, then plug-in the estimates as covariates in a regression. We show both theoretically and empirically that naively treating…

Econometrics · Economics 2025-05-01 Laura Battaglia , Timothy Christensen , Stephen Hansen , Szymon Sacher
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