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Related papers: On a diffuse interface model of tumor growth

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In this paper, we address an optimal distributed control problem for a non-local model of phase-field type, describing the evolution of tumour cells in presence of a nutrient. The model couples a non-local and viscous Cahn-Hilliard equation…

Analysis of PDEs · Mathematics 2023-10-25 Matteo Fornoni

Cancer is a very complex phenomenon that involves many different scales and situations. In this paper we consider a free boundary problem describing the evolution of a tumor colony and we derive a new asymptotic model for tumor growth. We…

Analysis of PDEs · Mathematics 2025-04-15 Rafael Granero-Belinchón , Martina Magliocca

This paper treats a distributed optimal control problem for a tumor growth model of Cahn-Hilliard type including chemotaxis. The evolution of the tumor fraction is governed by a variational inequality corresponding to a double obstacle…

Optimization and Control · Mathematics 2021-04-21 Pierluigi Colli , Andrea Signori , Jürgen Sprekels

We study a phase field model proposed recently in the context of tumour growth. The model couples a Cahn-Hilliard-Brinkman (CHB) system with a elliptic reaction-diffusion equation for a nutrient. The fluid velocity, governed by the Brinkman…

Analysis of PDEs · Mathematics 2019-09-06 Matthias Ebenbeck , Kei Fong Lam

We consider a phase-field model for the incompressible flow of two immiscible fluids. This model extends widespread models for two fluid phases by including a third, solid phase, which can evolve due to e.g. precipitation and dissolution.…

Analysis of PDEs · Mathematics 2022-05-18 Lars von Wolff , Iuliu Sorin Pop

We study the weak solvability of a system of coupled Allen-Cahn-like equations resembling cross-diffusion which is arising as a model for the consolidation of saturated porous media. Besides using energy like estimates, we cast the special…

Analysis of PDEs · Mathematics 2017-03-03 P. Artale Harris , E. N. M. Cirillo , A. Muntean

We investigate the mass-preserving $L^2$-gradient flow associated with a generalized Cahn--Hilliard equation. Our focus is on the sharp interface regime, where the interface width parameter $\varepsilon > 0$ is small. For well-prepared…

Analysis of PDEs · Mathematics 2025-12-02 Yuan Chen

This paper is concerned with a diffuse interface model for the gas-liquid phase transition. The model consists the compressible Navier-Stokes equations with van der Waals equation of state and a modified Allen-Cahn equation. The global…

Analysis of PDEs · Mathematics 2018-10-02 Qiaolin He , Ming Mei , Xiaoding Shi , Xiaoping Wang

In this paper we perform an asymptotic analysis for two different vanishing viscosity coefficients occurring in a phase field system of Cahn-Hilliard type that was recently introduced in order to approximate a tumor growth model. In…

Analysis of PDEs · Mathematics 2015-02-02 Pierluigi Colli , Gianni Gilardi , Elisabetta Rocca , Juergen Sprekels

In this paper, we investigate a system coupled by nonhomogeneous incompressible Navier-Stokes equations and Allen-Cahn equations describing a diffuse interface for two-phase flow of viscous fluids with different densities in a bounded…

Analysis of PDEs · Mathematics 2025-03-06 Yinghua Li , Wenlin Ye

We find analytical solutions to the Cahn-Hilliard equation for the dynamics of an interface in a system with a conserved order parameter (Model B). We show that, although steady-state solutions of Model B are unphysical in the far-field,…

Soft Condensed Matter · Physics 2009-10-30 R. M. L. Evans , M. E. Cates

An asymptotic analysis for a system with equation and dynamic boundary condition of Cahn-Hilliard type is carried out as the coefficient of the surface diffusion acting on the phase variable tends to 0, thus obtaining a forward-backward…

Analysis of PDEs · Mathematics 2021-06-03 Pierluigi Colli , Takeshi Fukao , Luca Scarpa

We propose a strange-attractor model of tumor growth and metastasis. It is a 4-dimensional spatio-temporal cancer model with strong nonlinear couplings. Even the same type of tumor is different in every patient both in size and appearance,…

Cell Behavior · Quantitative Biology 2008-10-28 Tijana T. Ivancevic , Murk J. Bottema , Lakhmi C. Jain

In this paper, we propose and analyze a diffuse interface model for inductionless magnetohydrodynamic fluids. The model couples a convective Cahn-Hilliard equation for the evolution of the interface, the Navier-Stokes system for fluid flow…

Analysis of PDEs · Mathematics 2023-12-20 Xiaodi Zhang

This article considers a limit system by passing to the limit in the following Cahn--Hilliard type phase field system related to tumor growth as $\beta\searrow0$: \begin{equation*} \begin{cases} \alpha\partial_{t} \mu_{\beta} + \partial_{t}…

Analysis of PDEs · Mathematics 2019-05-01 Shunsuke Kurima

Here we consider a Cahn-Hilliard-Navier-Stokes system characterized by a nonlocal Cahn-Hilliard equation with a singular (e.g., logarithmic) potential. This system originates from a diffuse interface model for incompressible isothermal…

Analysis of PDEs · Mathematics 2012-01-31 Sergio Frigeri , Maurizio Grasselli

We consider a random interface model on the discrete torus with $2n$ sites, obtained from the classical corner flip dynamics but with a weak global perturbation, namely an asymmetry of order $n^{-\gamma}$ of the direction of growth that…

Probability · Mathematics 2025-12-10 Patrícia Gonçalves , Martin Hairer , Maria Chiara Ricciuti

Tumor growth beyond a critical size relies on the development of a functional vascular network, which ensures adequate oxygen and nutrient supply. In this work, we present a modeling framework based on an optimization-based 3D-1D coupling…

Numerical Analysis · Mathematics 2026-04-01 Chiara Giverso , Denise Grappein , Stefano Scialò

We study the well-posedness of a modified degenerate Cahn-Hilliard type model for surface diffusion. With degenerate phase-dependent diffusion mobility and additional stabilizing function, this model is able to give the correct sharp…

Analysis of PDEs · Mathematics 2022-04-19 Xiaohua Niu , Yang Xiang , Xiaodong Yan

Various models of tumor growth are available in the litterature. A first class describes the evolution of the cell number density when considered as a continuous visco-elastic material with growth. A second class, describes the tumor as a…

Analysis of PDEs · Mathematics 2016-02-17 Benoit Perthame , Nicolas Vauchelet
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